Clinical trials · Raleigh–Durham, NC
Pediatrics clinical trials in Raleigh–Durham
We’re tracking 61 recruiting pediatrics studies with a site in or near Raleigh–Durham — including Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Cary, North CarolinaAges 10–65 - NCT03986021Recruiting
Track puberty, hormones, and periods across early teen years
This study follows girls before and after their first period to measure how reproductive hormones and menstrual cycles change over time. It may help researchers understand who is at higher risk for hormone and period problems, like PCOS.
Research Triangle Park, North CarolinaAges 8–65 - NCT02493478Recruiting
Improve safety during placing breathing tubes in children
This trial looks at ways to improve the safety and quality of emergency breathing tube placement in pediatric critical care and emergency settings. It may help reduce complications and improve how clinicians do these urgent procedures.
Raleigh, North CarolinaAges Any age - NCT06428175Recruiting
Hospital-to-home support for children with complex needs
This study tests a program to help children with complex medical needs and their families transition smoothly from the hospital to home. It focuses on improving communication and support during that critical time.
Durham, North CarolinaAges Up to 18 years - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Durham, North CarolinaAges Up to 21 years - NCT04775485RecruitingPhase 2
Targeted medicine for children with certain brain or solid tumors
This Phase 2 study tests tovorafenib, a targeted cancer medicine, in children and young adults whose tumors have specific BRAF or RAF changes. It is for cancers that have come back or grown despite previous treatment, with measurable signs on scans.
Durham, North CarolinaAges 6 months–25 years - NCT07166926Recruiting
Portable CT scanner for children at bedside
This study tests a portable CT scanner that can be brought to your child's bedside. It may help children who are too small or too sick to travel to the radiology department get the imaging they need.
Durham, North CarolinaAges Up to 5 years - NCT06847282Recruiting
Motor skills study for children with FSHD
This study looks at how children with FSHD move and function over time. It uses walking tests and optional MRI scans to understand muscle changes. Your child's participation could help researchers learn more about FSHD progression in kids.
Durham, North CarolinaAges 5–17 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Durham, North CarolinaAges 6–17 - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT07124078RecruitingPhase 2
Study of axatilimab for young people with chronic graft-versus-host disease
This study tests a new drug called axatilimab for children and teens with chronic graft-versus-host disease (cGVHD) that hasn't improved with standard treatments. The goal is to see if axatilimab works better than the usual care options. Participants will be randomly assigned to receive either axatilimab or one of several standard treatments.
Durham, North CarolinaAges 2–17 - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Durham, North CarolinaAges 1–18 - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Durham, North CarolinaAges 4 months–21 years - NCT05879835Recruiting
EDTA lock solution to prevent line blockages in children
This trial tests whether a solution called KiteLock (4% EDTA) put into a special feeding line can help prevent blockages in children who need long-term nutrition through the vein. It may reduce line occlusions (blockages) and the complications they can cause.
Durham, North CarolinaAges 4 weeks–18 years - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Durham, North CarolinaAges 6–18 - NCT05839379Recruiting
Targeted therapy study for children and young adults with brain tumors
This trial studies a targeted medicine approach for high-grade glioma (a fast-growing brain tumor) and some diffuse midline tumors, including DIPG. It may help by matching treatment to tumor biology using tumor testing done before or around starting standard therapy.
Durham, North CarolinaAges 1–39 - NCT06116422Recruiting
Food Insecurity Program for Healthy Baby Weight
This study tests a program to help families with food insecurity and early signs of obesity in infants. It aims to learn the best ways to support healthy weight in babies at risk for overweight.
Durham, North CarolinaAges 1–2 - NCT06177639Recruiting
A new eye camera designed for children and babies
This trial is testing a new, more comfortable eye camera designed for children and babies. It takes wide-angle pictures of the back of the eye (retina) to see if it works better than current cameras. You or your child can join even if you have healthy eyes or an eye condition.
Durham, North CarolinaAges 4 weeks+ - NCT05835310RecruitingPhase 3
IV anifrolumab for active lupus in children
This study tests whether an intravenous medicine called anifrolumab can safely improve active systemic lupus (SLE) in children. If you qualify, you may receive the study treatment and be closely monitored for safety and lupus symptoms.
Durham, North CarolinaAges 5–17 - NCT06639984RecruitingPhase 2
Psyllium for kids with IBS
This study tests if psyllium, a fiber supplement, helps reduce belly pain and other symptoms in children with irritable bowel syndrome (IBS). It may be an option if standard treatments haven't worked well.
Durham, North CarolinaAges 12–17 - NCT06139523Recruiting
Improving eye imaging in adults and children
This study aims to improve how we take pictures of the back of the eye (called OCT imaging) in both healthy adults and children. It will help doctors get better images to diagnose and manage eye conditions.
Durham, North CarolinaAges Any age - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Durham, North CarolinaAges 2 months–17 years - NCT06841575Recruiting
Better eye imaging for children and adults at Duke
This study tests a new camera that automatically adjusts to take clear pictures of the back of the eye. It aims to improve retinal imaging for healthy adults, adult eye clinic patients, and children seen at Duke Eye Center.
Durham, North CarolinaAges 1 month+ - NCT05090345Recruiting
Registry for young people getting bone marrow transplants
This trial is a registry that follows children and young adults up to age 26 who are having a bone marrow transplant, to better understand complications related to blood vessel and organ injury. It may help future patients by improving how doctors predict and prevent these problems.
Durham, North CarolinaAges birth–26 years
Hear when a new Pediatrics trial opens near Raleigh–Durham, NC
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Pediatrics trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting pediatrics studies listed above.
- Duke University Medical Center · 8 studies
- Duke Children's Hospital & Health Center · 3 studies
- Duke University · 3 studies
- Duke University Health System · 3 studies
- University of North Carolina at Chapel Hill · 3 studies
- Duke Cancer Center · 2 studies
- Duke Children's Primary Care North Durham
- Duke Health Center Creekstone
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pediatrics studies in North Carolina.
Common questions
- Are there pediatrics clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 61 recruiting pediatrics studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.