Clinical trials · Missouri
Pediatrics clinical trials in Missouri
We’re tracking 84 recruiting pediatrics studies with a site in Missouri — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Missouri
- NCT05634369RecruitingPhase 1/Phase 2
NK cell and chemotherapy trial for relapsed soft tissue sarcoma
This early-phase trial studies a type of immune cell treatment (NK cells) made from donor cells, given with chemotherapy drugs gemcitabine and docetaxel. It’s for children and young adults whose bone or soft tissue sarcoma has come back or hasn’t responded to prior treatment.
St Louis, MissouriAges 2–40 - NCT05521984RecruitingPhase 1
Dapagliflozin trial for children with hard-to-treat brain tumors
This Phase 1 trial tests whether dapagliflozin (an SGLT2 medicine) can help shrink or control certain pediatric brain tumors or other solid tumors that have come back or won’t respond. It’s designed mainly to check safety and early signs of effect in children and young adults who have limited treatment options.
St Louis, MissouriAges 6–21 - NCT00674388Recruiting
Improving care for children during anesthesia
This study aims to improve how anesthesia care is delivered to children in participating hospitals. Because it includes all children having anesthesia, it may help ensure safer, better care during procedures.
St Louis, MissouriAges Up to 21 years - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
St Louis, MissouriAges Up to 21 years - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Kansas City, MissouriAges 1 day–17 years - NCT05011422RecruitingPhase 1
Stem cell transplant using half-matched donor for kids with blood cancer
This study tests a special stem cell transplant for children and young adults with certain high-risk blood cancers or bone marrow diseases. It uses a half-matched family donor and a technique to remove specific cells, which may lower the risk of side effects and help the body accept the new cells.
St Louis, MissouriAges Up to 30 years - NCT04629014Recruiting
Quality of life study for kids with intestinal failure
This study looks at how children with intestinal failure feel and function day to day, using questionnaires. It aims to better understand quality of life to improve care for families managing specialized nutrition needs.
St Louis, MissouriAges 6 months–25 years - NCT03988283RecruitingPhase 1
Personalized DNA vaccine for recurrent childhood brain tumors
This trial tests a personalized DNA vaccine made from your tumor’s DNA (neoantigens) to help your immune system fight the cancer. It is designed for children and young adults with certain recurrent or newly diagnosed brain/spine tumors, after they have had other standard treatments and tumor tissue is available for testing.
St Louis, MissouriAges Up to 25 years - NCT01696721Recruiting
Pediatric radiation therapy registry for children under 22
This study is a registry that collects information from children and teens who receive radiation therapy at participating hospitals. It helps researchers learn how radiation is used in pediatrics and may improve future care.
St Louis, MissouriAges Up to 21 years - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
St Louis, MissouriAges 2 days–17 years - NCT07192952RecruitingPhase 3
Long-term safety of finerenone for children with heart failure
This trial tests a medicine called finerenone to see if it is safe for children and young adults with heart failure when taken for a long time. It may help improve heart function and manage symptoms.
Kansas City, MissouriAges Up to 18 years - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Kansas City, MissouriAges 6 months–17 years - NCT07770659Recruiting
Using MRI to detect early heart transplant rejection
This study tests whether a heart MRI can detect early signs of organ rejection after a heart transplant. If successful, it could reduce the need for frequent biopsies.
St Louis, MissouriAges 6–25 - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Kansas City, MissouriAges 4 months–21 years - NCT07630974RecruitingPhase 1/Phase 2
New Cancer Drug for Children With Hard-to-Treat Solid Tumors
This trial tests a new drug called ifinatamab deruxtecan in children whose solid tumors (cancers that form lumps, excluding brain tumors) have come back or stopped responding to previous treatments. The drug is designed to target and kill cancer cells while potentially causing fewer side effects than standard chemotherapy.
Kansas City, MissouriAges 1 month–17 years - NCT07577336Recruiting
Portable MRI for children with oxygen-related brain injury
This study tests whether a small, portable MRI scanner can safely take pictures of the brain in seriously ill children who may have brain injury from lack of oxygen. It could help doctors diagnose and treat these children faster, without moving them from the ICU.
Kansas City, MissouriAges Up to 17 years - NCT07494045RecruitingPhase 2
Study of CTAP101 for kids with chronic kidney disease
This study tests a new extended-release capsule (CTAP101) for children aged 8 to under 18 with moderate to severe chronic kidney disease (CKD). The goal is to see how the drug works in the body, if it's safe, and if it can help control mineral and hormone levels that are often out of balance in CKD.
Kansas City, MissouriAges 1 month–17 years - NCT07458568Recruiting
ViBandz study for children with movement problems
This study tests a wearable device called ViBandz that gives gentle vibrations to help children with neurologic conditions move better. It is for children who are already scheduled to receive this type of vibration therapy as part of their regular care at Children's Mercy Hospital.
Kansas City, MissouriAges 6 months–17 years - NCT07287982RecruitingPhase 2
ARGX-119 for children with SMA who can walk
This study tests a new medicine called ARGX-119 in children with SMA. It is given through an IV and aims to help kids who can already walk get stronger and stay healthy.
Columbia, MissouriAges 5–17 - NCT07278778Recruiting
Cancer Care Companion for parents of children with cancer
This study tests a digital tool called Cancer Care Companion to help parents of children newly diagnosed with cancer. It aims to provide support and resources during your child's treatment journey.
St Louis, MissouriAges 18 years+ - NCT05855083RecruitingPhase 2
Narsoplimab for high-risk TMA after bone marrow transplant
This trial studies the medicine narsoplimab in children who develop a serious complication called HSCT-TMA after a bone marrow transplant. It aims to improve safety and effectiveness for high-risk cases where the condition is ongoing or causing organ problems.
St Louis, MissouriAges 4 weeks–17 years - NCT04775485RecruitingPhase 2
Targeted medicine for children with certain brain or solid tumors
This Phase 2 study tests tovorafenib, a targeted cancer medicine, in children and young adults whose tumors have specific BRAF or RAF changes. It is for cancers that have come back or grown despite previous treatment, with measurable signs on scans.
St Louis, MissouriAges 6 months–25 years - NCT07195032RecruitingPhase 4
MMR vaccine safety in kids after heart transplant
This trial tests whether the MMR (measles, mumps, rubella) vaccine is safe and works well for children who have had a heart transplant. It may help protect you from these diseases if you haven't had the vaccine or no longer have immunity.
Kansas City, MissouriAges 1–17 - NCT03509961RecruitingPhase 2
Reducing total body radiation for children with leukemia transplants
This study looks at whether some children and young adults with B-ALL can safely get a transplant without total body irradiation (TBI), based on special leukemia test results. It’s meant to help lower radiation-related risks while keeping leukemia control strong.
Kansas City, MissouriAges 1–25
Pediatrics trials by city in Missouri
Where these studies are running in Missouri
Institutions with a site for the recruiting pediatrics studies listed above.
- Children's Mercy Kansas City · 4 studies
- St. Louis Children's Hospital · 4 studies
- Washington University in St. Louis · 4 studies
- Children's Mercy Hospital · 3 studies
- Mercy Children's Hospital
- Omeros Investigational Site
- OPKO Site
- SSM Cardinal Glennon Health Care System
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pediatrics trials in other states
Common questions
- Are there pediatrics clinical trials in Missouri?
- Yes. We're currently tracking 84 recruiting pediatrics studies with a site in Missouri, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study in Missouri?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Missouri to take part?
- Not necessarily. These studies have a site in Missouri, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open in Missouri regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.