Clinical trials · North Carolina
Pediatrics clinical trials in North Carolina
We’re tracking 92 recruiting pediatrics studies with a site in North Carolina — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT07166926Recruiting
Portable CT scanner for children at bedside
This study tests a portable CT scanner that can be brought to your child's bedside. It may help children who are too small or too sick to travel to the radiology department get the imaging they need.
Durham, North CarolinaAges Up to 5 years - NCT06789666Recruiting
Digital art therapy for young cancer survivors
This trial is testing a digital art therapy program designed to help young adults who survived childhood cancer feel better emotionally. You'll use an app to create art and connect with others, all from home.
Chapel Hill, North CarolinaAges 18–25 - NCT05634369RecruitingPhase 1/Phase 2
NK cell and chemotherapy trial for relapsed soft tissue sarcoma
This early-phase trial studies a type of immune cell treatment (NK cells) made from donor cells, given with chemotherapy drugs gemcitabine and docetaxel. It’s for children and young adults whose bone or soft tissue sarcoma has come back or hasn’t responded to prior treatment.
Durham, North CarolinaAges 2–40 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Durham, North CarolinaAges 1–18 - NCT05608668Recruiting
Breathing and activity coaching for kids with obesity and mild asthma
This trial tests an “inspiratory pulmonary rehabilitation” program—guided breathing and exercise training—for children who have obesity and mild asthma. It may help improve breathing control and exercise ability by teaching safe, structured breathing and activity habits.
Durham, North CarolinaAges 8–17 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Charlotte, North CarolinaAges Up to 21 years - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Durham, North CarolinaAges 1 day–17 years - NCT05058508Recruiting
Exercise program for children and young adults on new cancer treatment
This study tests an exercise program for young people newly diagnosed with cancer who are starting treatment like chemotherapy. It aims to see whether safely adding exercise can be part of care during the first treatment cycles.
Charlotte, North CarolinaAges 2–25 - NCT04948619RecruitingPhase 2
Vaccine response after cancer therapy in kids
This study is checking how well the immune system works and responds to vaccines in children and young adults who have recently finished cancer treatment. It may help doctors understand if vaccines are safe and effective after therapy.
Charlotte, North CarolinaAges 2–21 - NCT04629014Recruiting
Quality of life study for kids with intestinal failure
This study looks at how children with intestinal failure feel and function day to day, using questionnaires. It aims to better understand quality of life to improve care for families managing specialized nutrition needs.
Durham, North CarolinaAges 6 months–25 years - NCT01286519Recruiting
Study of how off-label medicines work in young children
This trial measures how medicines behave in the body when they are used in children younger than 8 years for a reason or dose not listed on the official FDA label. It may help doctors choose safer, better doses for children in the future.
Chapel Hill, North CarolinaAges 1 day–8 years - NCT01696721Recruiting
Pediatric radiation therapy registry for children under 22
This study is a registry that collects information from children and teens who receive radiation therapy at participating hospitals. It helps researchers learn how radiation is used in pediatrics and may improve future care.
Chapel Hill, North CarolinaAges Up to 21 years - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Chapel Hill, North CarolinaAges 6–11 - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Durham, North CarolinaAges 4 months–21 years - NCT07634653Recruiting
Strength Training for Kids with Newly Diagnosed Blood Cancer
This study tests whether strength training exercises during cancer treatment can help children with acute lymphoblastic leukemia or lymphoblastic lymphoma feel stronger and recover better. The research includes optional interviews with parents to understand how the program affects families.
Chapel Hill, North CarolinaAges 6 years+ - NCT07605429RecruitingPhase 3
Rugonersen treatment for Angelman syndrome
This study tests a new medicine called rugonersen for people with Angelman syndrome. The medicine is given as an injection into the fluid around the spinal cord and may help improve symptoms by targeting the genetic cause of the condition.
Chapel Hill, North CarolinaAges 1–50 - NCT05476770RecruitingPhase 1
Tagraxofusp for children with CD123-positive leukemia
This study tests tagraxofusp, a medicine that targets a marker called CD123 on cancer cells, in children and young adults whose leukemia or lymphoma has come back or is resistant to treatment. It may help by shrinking the cancer and improving disease control after standard therapies have not worked.
Charlotte, North CarolinaAges 1–21 - NCT07581938Recruiting
Early Dental Screening for Sleep Problems in Kids
This study uses a smartphone app and a wearable device to check for early signs of sleep-disordered breathing—a condition where breathing stops briefly during sleep—in children ages 8–13. The goal is to catch dental and jaw problems that might lead to sleep issues before they become serious.
Chapel Hill, North CarolinaAges 8–13 - NCT07390773Recruiting
Supporting decisions for critically ill children
This study tests a program called BRIDGE that helps parents, doctors, and nurses talk about difficult medical decisions for seriously ill children. It focuses on improving communication and understanding between families and the care team.
Durham, North CarolinaAges Any age - NCT04457154Recruiting
Registry for teens and young adults with OSA who can’t use CPAP
This study collects information in a registry to help doctors understand outcomes for young people with moderate-to-severe obstructive sleep apnea who cannot use CPAP and may use an implantable breathing stimulation device. You might qualify if you’ve tried and couldn’t tolerate CPAP and you’re able/willing to get and use the device and return for follow-ups and sleep tests.
Durham, North CarolinaAges 18–21 - NCT07287982RecruitingPhase 2
ARGX-119 for children with SMA who can walk
This study tests a new medicine called ARGX-119 in children with SMA. It is given through an IV and aims to help kids who can already walk get stronger and stay healthy.
Hillsborough, North CarolinaAges 5–17
Pediatrics trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting pediatrics studies listed above.
- Duke University Medical Center · 6 studies
- Atrium Health Levine Children's Hospital · 2 studies
- Duke Healthy Lifestyles Clinic · 2 studies
- Levine Cancer Institute · 2 studies
- University of North Carolina · 2 studies
- Atrium Health
- Carolina-Levine Children's Hospital
- Duke Children's Hospital & Health Center
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pediatrics trials in other states
Common questions
- Are there pediatrics clinical trials in North Carolina?
- Yes. We're currently tracking 92 recruiting pediatrics studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.