Clinical trials
Pediatrics clinical trials
Below are recruiting pediatrics clinical trials, each written for real people, not researchers. We’re tracking 1,386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05622461Recruiting
Recovery support program for children after traumatic brain injury
This trial supports families during the early weeks after a child’s brain injury and hospital stay. It aims to help caregivers and children move toward recovery with better support after discharge.
Cincinnati, OhioAges 18 years+ - NCT05633693Recruiting
Exercises to help children with fainting and blood-pressure drops
This study tests whether teaching special standing/balance movements can reduce fainting episodes in children who have recurring vasovagal fainting or certain forms of POTS. It may help your child feel more stable when standing and improve symptoms, while researchers measure balance and “counterpressure” responses during the tests.
Burnaby, British ColumbiaAges 6–18 - NCT05642455RecruitingPhase 1/Phase 2
Study of a new treatment for certain childhood cancers
This Phase 1/2 study tests a new therapy for children and young adults with specific types of cancer that have been treated with chemotherapy before. It may help by targeting cancer features in the tumor and using your immune system in a controlled way.
Palo Alto, CaliforniaAges 2–21 - NCT05645718RecruitingPhase 2
Chemo plus targeted antibodies for relapsed childhood B-ALL
This Phase 2 study tests a combination treatment for children, teens, or young adults whose B-cell acute lymphoblastic leukemia (B-ALL) has come back or did not respond to initial therapy. It may help patients who cannot safely receive certain standard medicines like anthracyclines or who cannot tolerate PEG-asparaginase.
Houston, TexasAges 1–25 - NCT05658640RecruitingPhase 1/Phase 2
Testing trametinib and steroid plus chemo for relapsed blood cancers
This early-phase trial tests whether adding trametinib and dexamethasone to standard chemotherapy can improve outcomes for children whose blood cancer has come back or did not respond. Because it is a Phase 1/2 study, the main goal is to see safety and learn the best way to treat your specific cancer type.
ViennaAges 1–21 - NCT05658731Recruiting
Radiation planning study to protect thinking in children
This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.
Washington D.C., District of ColumbiaAges 1–26 - NCT05660473RecruitingPhase 2
Study of venetoclax plus chemotherapy for Ph-negative ALL
This Phase 2 trial tests whether adding venetoclax to a chemotherapy plan works better for Philadelphia chromosome–negative acute lymphoblastic leukemia (ALL). It may help people achieve deeper remission by targeting leukemia cells in a different way than chemotherapy alone.
TianjinAges 14–60 - NCT05667506RecruitingPhase 1/Phase 2
Check CNCT19 cell therapy for relapsed childhood ALL
This early-stage trial tests a personalized immune-cell treatment called CNCT19 in children and teens whose leukemia (ALL) has come back or not responded to prior therapy. It may help the immune system recognize and attack leukemia cells that carry CD19.
Hefei, AnhuiAges 3–18 - NCT05674656RecruitingPhase 1/Phase 2
Testing dolutegravir and rilpivirine in HIV-positive children
This study checks how safe and well two HIV medicines work in children ages 6 to under 12. It also measures drug levels in the body to guide dosing and watch for side effects.
Long Beach, CaliforniaAges 6–12 - NCT05674643Recruiting
Gastric testing during children’s surgery
This trial studies how the stomach is working in children around the time of surgery. It may help improve how doctors assess and manage stomach function to make surgery safer and more comfortable.
Boston, MassachusettsAges 2–18 - NCT05682378RecruitingPhase 3
Long-term follow-up for inclisiran in young people with inherited high cholesterol
This study follows people with HeFH or HoFH (inherited high cholesterol) who previously took inclisiran in specific pediatric ORION studies. It mainly checks long-term safety and how well the treatment continues to be tolerated over time.
Boca Raton, FloridaAges 12–100 - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Birmingham, AlabamaAges 2–18 - NCT05717712RecruitingPhase 1
Study virus treatment for newly diagnosed DIPG in children
This Phase 1 trial tests a type of cancer-fighting virus given directly into the tumor for children with newly diagnosed diffuse intrinsic pontine glioma (DIPG). The goal is to see if it can be delivered safely and to learn how the body responds to it.
Beijing, Beijing MunicipalityAges 1–18 - NCT05717699RecruitingPhase 1
Trial of a virus treatment for DIPG in children
This Phase 1 trial tests a lab-made cancer virus (Ad-TD-nsIL12) in children with DIPG whose tumor keeps growing after standard treatment. It mainly focuses on safety and how the treatment works, and it may help shrink or control the tumor by stimulating the immune system.
Beijing, Beijing MunicipalityAges 1–18 - NCT05724446RecruitingPhase 3
Steroid eye drops for inflammation after cataract surgery in young children
This study tests whether a clobetasol steroid eye drop (a nanoemulsion) reduces eye inflammation after cataract surgery in babies and toddlers. It may help protect comfort and eye healing after surgery.
BarcelonaAges birth–3 years - NCT05726591Recruiting
Robotic exoskeleton study to improve walking in children
This study looks at how safely using a pediatric robotic exoskeleton over the long term can improve how children walk. It’s for children ages 3–17 who have certain movement or spine-related conditions and who can meet walking and joint-movement requirements.
Bethesda, MarylandAges 3–17 - NCT05731024Recruiting
Closed-loop breathing control vs standard care for kids in ICU
This study compares a computerized “closed-loop” system that helps match breathing support to a child’s needs versus usual (standard) breathing control. It’s for critically ill children on a breathing machine, aiming to improve synchronization between the child and the ventilator.
AydinAges 1 month–18 years - NCT05734066RecruitingPhase 1/Phase 2
Lurbinectedin drug study for young people with Ewing sarcoma
This trial tests lurbinectedin, a cancer medicine, by itself (no other drugs) in children and young adults whose Ewing sarcoma has come back or did not respond to prior treatment. It aims to see how safe the drug is and whether it can help control the cancer.
Los Angeles, CaliforniaAges 2–30 - NCT05740254Recruiting
Compare early versus late eating times for teen obesity
This study tests whether having a shorter daily eating schedule earlier in the day works better than a later eating schedule for reducing weight and improving health in teens with obesity. Participants will also follow planned fasting (not eating) periods and complete regular check-ins.
Los Angeles, CaliforniaAges 12–21 - NCT05749419Recruiting
Vaccines for children with disabilities and long-term conditions
This study looks at how vaccines work in children who have disabilities, long-term (chronic) illnesses, or conditions they were born with. It may help improve vaccine care for kids who need extra support.
JerusalemAges Any age - NCT05754840RecruitingPhase 1/Phase 2
Cannabinoid treatment for children with hard-to-treat cancers
This early-phase study tests whether a cannabinoid medicine (including nabilone/cannabis-based treatment) can be given safely to children and teens with relapsed or refractory cancer. It may help with treatment options for children whose cancer has come back or did not respond to standard therapy.
Vancouver, British ColumbiaAges 4–18 - NCT05756309Recruiting
ECG patch test to improve heart rhythm detection in kids
This study checks whether a wearable ECG patch can correctly record heart electrical signals and help identify abnormal rhythms (arrhythmias) in children. If it works well, it could make future heart rhythm monitoring more accurate for pediatric patients who need regular Holter (long ECG) monitoring.
SeoulAges 4 weeks–19 years - NCT05763953RecruitingPhase 2
Nasal medicine trial for fast heart rhythm in children
This Phase 2 trial tests whether an at-home nasal spray medicine called etripamil can help children who have episodes of a specific type of fast, irregular rhythm caused by an electrical “AV node” circuit. It mainly targets certain kids with past or confirmed episodes on heart testing.
Phoenix, ArizonaAges 6–17 - NCT05783323RecruitingPhase 2
Larotrectinib plus radiation for thyroid cancer with NTRK fusion
This Phase 2 trial tests larotrectinib (a targeted medicine) to help radioactive iodine (RAI) work better in people with differentiated thyroid cancer that has an NTRK gene fusion. It may improve how much thyroid cancer the RAI can reach and shrink.
San Francisco, CaliforniaAges 2–99
Hear when a new Pediatrics trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pediatrics?
- Yes. Clin2 currently lists 1,386 recruiting pediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.