Clinical trials
Pediatrics clinical trials
Below are recruiting pediatrics clinical trials, each written for real people, not researchers. We’re tracking 1,387 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05441813RecruitingPhase 2
Coconut oil mouth rinse to prevent mouth sores during transplant
This study tests whether a coconut oil mouth rinse can help prevent mouth sores in children and young adults who are about to receive intense chemotherapy for a stem cell transplant. If mouth sores can be prevented, it may make treatment more comfortable and reduce complications.
Charlotte, North CarolinaAges 7–26 - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT05457140Recruiting
Testing genes and other samples in youth with first psychosis
This study looks at many types of tests (including genetic testing and other lab data) to help understand what may be causing first-time psychosis symptoms in youth. It may help doctors learn more about the condition for future care, and it can involve analyzing family genetic information.
San Diego, CaliforniaAges 7–17 - NCT05457829RecruitingPhase 2
Testing two chemotherapy combinations for relapsed pediatric rhabdomyosarcoma
This trial compares two treatment combinations—liposomal doxorubicin plus irinotecan versus a different chemotherapy plan—in children and teens whose rhabdomyosarcoma came back or did not respond. It aims to see which option works better and is safer for children who have had prior cancer treatment.
GuangzhouAges 6 months–18 years - NCT05464888Recruiting
Animal-assisted therapy for kids’ dental visits
This study tests whether working with a trained animal can make dental checkups and cleanings easier for children ages 4 to 8. It may help reduce fear and improve how kids tolerate routine dental care.
Chapel Hill, North CarolinaAges 4–8 - NCT05469373Recruiting
Testing ESIS for children with hard-to-treat epilepsy
This trial studies ESIS in children and teens (ages 1 to 30) who have epilepsy that has not been controlled by medications. It may help by improving how doctors evaluate and treat seizures, especially when an additional brain-monitoring test is planned.
Cincinnati, OhioAges 1–30 - NCT05471232Recruiting
Genomic testing for youth mental health crises with IDD
This study looks at genetic (DNA) information to understand mental health crises in youth with intellectual and developmental disabilities. It may help doctors learn why these crises happen and improve how future families are supported.
San Diego, CaliforniaAges 7–17 - NCT05476770RecruitingPhase 1
Tagraxofusp for children with CD123-positive leukemia
This study tests tagraxofusp, a medicine that targets a marker called CD123 on cancer cells, in children and young adults whose leukemia or lymphoma has come back or is resistant to treatment. It may help by shrinking the cancer and improving disease control after standard therapies have not worked.
Los Angeles, CaliforniaAges 1–21 - NCT05477589RecruitingPhase 3
Conditioning plan for kids with AML before stem cell transplant
This Phase 3 trial studies the best “conditioning” chemotherapy plan before an allogeneic stem cell transplant for children with AML. It may help improve outcomes by testing an approach for kids who are ready for transplant after relapse or specific high-risk features.
BrusselsAges Up to 18 years - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT05481437Recruiting
Surveying brentuximab for children with Hodgkin lymphoma
This trial is a survey study that looks at how brentuximab vedotin is used in children with Hodgkin lymphoma. It focuses on people whose tumor is CD30-positive and who have not had prior treatment, to see how the drug fits with a standard chemotherapy plan (AVD).
Tokyo, TokyoAges Up to 18 years - NCT05480930Recruiting
Improving nighttime care access for sick children in Haiti
This program tries to improve how quickly children with sudden (acute) illnesses can get help during nighttime hours in Haiti. It involves connecting families to the study team by phone and, in some cases, through a household visit.
Gressier, OuestAges Up to 10 years - NCT05483166Recruiting
Parent coaching to support memory and behavior after childhood cancer
This pilot study tests a program that works with parents to support a child’s thinking, memory, and behavior after childhood cancer treatment. It may help by teaching parents strategies to support school and day-to-day functioning.
AarhusAges 10–17 - NCT05491525RecruitingPhase 2/Phase 3
Vibegron for children with nerve bladder using intermittent catheter
This study tests how well and how safely vibegron works long-term in children (ages 2 to under 18) with a nerve-related bladder condition, who regularly use intermittent catheterization. It also tracks how the body processes the medicine and whether it helps bladder control over time.
Little Rock, ArkansasAges 2–17 - NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Los Angeles, CaliforniaAges 2–17 - NCT05512169Recruiting
Genetic study in Indian children with newly diagnosed leukemia
This study looks at genetic (DNA) differences to understand acute lymphoblastic leukemia (ALL) in Indian children and how treatments may fit better. You may be able to join if your child is newly diagnosed, meets the study’s treatment plan rules, and provides consent.
New DelhiAges 1–18 - NCT05518383RecruitingPhase 4
Pediatric B-cell lymphoma treatment study using established care
This trial studies treatment for children and teens with certain B-cell non-Hodgkin lymphomas using a specific treatment protocol. It may help doctors confirm how well the regimen works in young patients and improve care over time.
Moscow, RFAges 1 day–18 years - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT05538208RecruitingPhase 2
Children with lupus kidney inflammation using mycophenolate
This Phase 2 study tests how well the medicine mycophenolate mofetil (MMF) works for children and teens with lupus nephritis that is “proliferative” (a specific biopsy type). You may qualify if your kidney biopsy and current treatment match the study’s targets and you can follow frequent visits and testing.
San Francisco, CaliforniaAges 8–20 - NCT05544019RecruitingPhase 1
Testing an investigational drug for mature B-cell cancers
This early (Phase 1) study tests SGR-1505, an experimental treatment, in people with certain mature B-cell cancers. It’s mainly designed to see how the drug works in the body and to check safety, and it may offer an option if standard treatments aren’t enough.
Gilbert, ArizonaAges 18 years+ - NCT05549258RecruitingPhase 2
Inebilizumab for children with NMOSD who had recent relapses
This trial studies whether inebilizumab can reduce illness activity in children with neuromyelitis optica spectrum disorder (NMOSD), a condition that can cause attacks affecting the eyes and spinal cord. It focuses on kids who have had recent relapses, meaning symptoms came back or worsened.
La Jolla, CaliforniaAges 2–17 - NCT05550324Recruiting
Pediatric heart disease patient data repository
This trial is a data repository that collects information from children with heart (cardiovascular) conditions and related syndromes. It focuses on organizing cases and comparing groups to help researchers better understand pediatric heart disease.
Columbus, OhioAges Any age - NCT05552287RecruitingPhase 4
Infliximab drug levels in children with Crohn’s disease
This study measures how infliximab (a medicine that calms immune inflammation) moves through the body in children with Crohn’s disease. It mainly helps doctors understand dosing and drug levels, especially when treatment is newly starting.
RotterdamAges 1–15 - NCT05553899Recruiting
PET-MRI scans for monitoring children’s brain tumor return
This study checks whether a special scan called PET-MRI can better tell if a child’s brain tumor has come back after treatment. It may help doctors decide faster and more accurately when changes seen on regular MRI are true tumor recurrence.
Sheffield, South YorkshireAges 8–18
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Common questions
- Are there clinical trials for pediatrics?
- Yes. Clin2 currently lists 1,387 recruiting pediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.