Clinical trials
Perimenopause clinical trials
Below are recruiting perimenopause clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07590999Recruiting
Probiotics and Menopause Symptoms: A Research Study
This study tests whether taking a probiotic supplement helps with hot flushes, mood changes, and other symptoms of perimenopause (the years around menopause). Researchers believe gut health may play a role in these symptoms.
Oxford, EnglandAges 45–60 - NCT07022925Recruiting
Wearable device for tracking hot flushes in perimenopause
This study will test if a wearable device can accurately track symptoms like hot flushes and night sweats in women going through perimenopause. If you are between 35 and 55 and experiencing these symptoms, your participation could help improve future symptom monitoring.
London, OntarioAges 35–55 - NCT07599930Recruiting
Novel Snack for Perimenopausal Symptoms and Wellness
This study tests whether a specially designed snack can help reduce hot flashes, night sweats, mood changes, and other symptoms that happen during perimenopause (the years leading up to menopause). You'll eat the snack regularly and answer questions about how you feel.
London, LondonAges 40–55 - NCT07378787Recruiting
Time-restricted eating and low glycemic diet for menopause
This study tests if combining time-restricted eating with a low glycemic index diet can improve memory, slow aging, and boost metabolism in women going through perimenopause or menopause. It aims to see if this eating pattern helps with brain health and body changes during this life stage.
ZagrebAges 45–75 - NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT07427459Recruiting
Brain retraining program for perimenopause symptom management
This trial tests a brain retraining program (focusing on the amygdala and insula) to help manage symptoms of perimenopause. It aims to see if this approach can reduce discomfort and improve well-being during this transition.
Decorah, IowaAges 38–60 - NCT07251296Recruiting
Exercise and supplement study for menopausal women
This study tests whether a program of functional exercise combined with a nutritional supplement can help improve symptoms like hot flashes, sleep, and mood in women going through menopause. It may be a good fit if you are between 45 and 65, have moderate menopause symptoms, are not very active, and are not using hormone therapy or certain medications.
Valencia, ValenciaAges 45–65 - NCT07272174Recruiting
Exercise during perimenopause to boost thinking and memory
This trial tests whether a strength-training program can help improve memory and thinking for women going through perimenopause. If you are between 40 and 55, still have your uterus, and notice changes in your memory, you may be able to join.
Vancouver, British ColumbiaAges 40–55 - NCT07481513Recruiting
Intermittent fasting for perimenopausal women's mental health
This study tests whether intermittent fasting can improve mental health in women going through perimenopause (the years around menopause). If you're a woman aged 45-55 in this stage and not on certain treatments, this trial may help you understand how diet affects your mood.
BeirutAges 45–55 - NCT07606755RecruitingPhase 4
Jinfeng Pill for Hot Flashes and Menopause Symptoms
This study tests whether a traditional Chinese medicine called Jinfeng Pill can reduce hot flashes, night sweats, sleep problems, mood changes, and other symptoms during perimenopause (the transition to menopause, typically ages 45–55). Researchers want to see if this treatment works better than standard options.
Wuhan, HubeiAges 45–55 - NCT03951194RecruitingPhase 2/Phase 3
Platelet-rich plasma infusion for perimenopausal women
This trial tests whether infusing a concentration of your own blood platelets into the ovary can help regulate menstrual cycles and improve ovarian function in women going through perimenopause.
AthensAges 40–50 - NCT07688720Recruiting
Ear nerve stimulation for PMDD and perimenopause
This study tests whether a gentle electrical stimulation on the ear can help people with premenstrual dysphoric disorder (PMDD) or perimenopause symptoms. You would use a small device at home and fill out online surveys.
Fort Worth, TexasAges 18–55 - NCT06865066Recruiting
Online therapy for anxiety during perimenopause
This study tests if an online therapy program (based on cognitive behavioural therapy) can help reduce anxiety in women going through perimenopause. The therapy is done over the internet, so you can participate from home.
Kingston, OntarioAges 40–60 - NCT06976112Recruiting
Lean pork and heart health in perimenopause
This study tests whether adding lean pork to your diet can improve blood vessel function during perimenopause. You may be eligible if you are a woman between 40 and 55, have irregular periods, and have high blood pressure but not diabetes.
Baton Rouge, LouisianaAges 40–55 - NCT07120997Recruiting
Prunes to prevent bone loss during perimenopause
This study tests whether eating prunes every day can help prevent bone loss in women going through perimenopause. If you are between 44 and 55, not severely obese, and have irregular periods, you may be able to join.
University Park, PennsylvaniaAges 44–55 - NCT07135232Recruiting
Strength training and plant supplement for menopause symptoms
This 6-month study tests if strength training plus a plant-based supplement can help with perimenopause symptoms and muscle health. It's for women ages 40-55 who are not on hormone therapy and not already doing heavy resistance training.
Leeds, North HumbersideAges 40–55 - NCT07501377Recruiting
Diet and brain health study for women in menopause with overweight
This trial tests whether a diet rich in fiber and plant compounds (polyphenols) can reduce brain inflammation in perimenopausal women who are overweight. If you're in early menopause and have some inflammation, this study may show how diet affects your brain health.
Leipzig, SaxonyAges 35–60 - NCT06826755Recruiting
Melatonin for heart health in midlife women
This study tests whether melatonin can help improve heart health in midlife women with high blood pressure. It involves taking a melatonin pill or placebo for several weeks and checking blood pressure and other health markers.
Rochester, MinnesotaAges 40–55 - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT07615777Recruiting
Nutritional supplements for midlife women's health symptoms
This study tests whether special nutritional supplements can help women aged 38–55 who are experiencing irregular periods or midlife symptoms like hot flushes, sleep problems, or mood changes. The goal is to see if these supplements improve overall health markers and how you feel.
Southampton, HampshireAges 38–55 - NCT06419972Recruiting
Multimodal program for women in menopause transition
This study tests a program combining different therapies to help women during the menopause transition. It aims to improve symptoms and quality of life.
ValenciaAges 45–85 - NCT07333885Recruiting
Reducose® for blood sugar and menopause symptoms in perimenopausal women
This trial tests whether a supplement called Reducose® can help manage blood sugar and menopause symptoms in women ages 40-60 who are perimenopausal (having irregular periods). You'll wear a continuous glucose monitor and use a phone app for up to 12 weeks.
Los Angeles, CaliforniaAges 40–60 - NCT06852755Recruiting
Finding markers to track menopause in women
This study looks for biological signs that can help monitor menopause. It may help women understand their menopause transition better.
New Taipei CityAges 20 years+ - NCT07309692Recruiting
Evaluating abnormal bleeding in perimenopause
This study compares different ways to evaluate abnormal uterine bleeding in women aged 40-55 who are perimenopausal. It aims to find the best method to diagnose the cause of bleeding.
SohagAges 40–55
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Common questions
- Are there clinical trials for perimenopause?
- Yes. Clin2 currently lists 36 recruiting perimenopause studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perimenopause trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perimenopause trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.