Clinical trials
Perineal Laceration, Tear, or Rupture During Delivery clinical trials
Below are recruiting perineal laceration, tear, or rupture during delivery clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07170007Recruiting
Physiotherapy after birth trauma for first-time mothers
This study tests a special physiotherapy program for first-time mothers who had a vaginal tear or episiotomy during childbirth. The goal is to see if it helps recovery better than standard care.
Ribeirão Preto, São PauloAges 18 years+ - NCT07499752Enrolling by invitation
Study on fewer tears: Local anesthesia for first vaginal birth
This study tests whether using local anesthesia during your first vaginal birth can reduce the risk of perineal tears. It aims to make childbirth safer and more comfortable.
StockholmAges 18–64 - NCT07124676Recruiting
Comparing two systems for classifying second-degree vaginal tears after childbirth
This study looks at two different ways to classify second-degree tears that happen during a vaginal birth. The goal is to see which system better predicts problems after delivery, helping doctors provide the best care.
Naples, ItalyAges 18 years+ - NCT04047849RecruitingPhase 4
Antibiotics for early water breaking before 23 weeks
This trial studies whether taking antibiotics can help in pregnancies where the “water” broke early (before 23 weeks) but you don’t have a fever. It aims to reduce complications while keeping both mother and baby as safe as possible.
Baton Rouge, LouisianaAges 18 years+ - NCT05469984Recruiting
Two antibiotic plans for water breaking before labor
This trial compares two different “preventive” antibiotic schedules for pregnant people whose water breaks more than 18 hours before labor, or who go into preterm labor. The goal is to see which plan better helps mother and baby by reducing infection-related complications.
NahariyaAges 18–48 - NCT07005063Recruiting
Rotator cuff repair with FiberLocker patch
This trial tests a new patch, FiberLocker, to help repair a torn rotator cuff tendon. It's for people who need surgery for a full-thickness tear caused by an injury, and aims to improve healing.
Zurich, Canton of ZurichAges 40–65 - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT06332911Recruiting
Shockwave balloon to help place aortic stent graft
This trial tests a special balloon that uses shock waves to crack calcium in the iliac arteries, making room for a larger aortic stent graft. It is for people with a bulging aorta (aneurysm) who also have heavily calcified or narrow iliac arteries that would otherwise prevent the graft from passing through.
Münich, BavariaAges 18 years+ - NCT06605118RecruitingPhase 3
Azithromycin to prevent infection in planned C-section
This trial tests whether a single dose of the antibiotic azithromycin before a planned C-section can prevent infections after delivery. It is for pregnant people with a singleton or twins who are not in labor or have not had their water break.
Birmingham, AlabamaAges Any age - NCT07826533Recruiting
Intravenous papaverine for term prelabour rupture of membranes
This study tests whether giving papaverine through a vein can help start labour in women whose water has broken but who are not yet having contractions. Papaverine is a medicine that relaxes smooth muscles, which may help the cervix prepare for delivery.
HolonAges Any age - NCT07717502Recruiting
Comparing two ways to ripen the cervix for labor induction
This trial tests two different methods of preparing the cervix for labor induction in first-time mothers. The goal is to see which approach is more likely to lead to a vaginal delivery.
New Orleans, LouisianaAges 18 years+ - NCT06506721Recruiting
Comparing two devices for labor induction after one C-section
This study compares two medical devices used to start labor in women who have had one previous C-section and whose cervix is not yet ready. It aims to find which device works best for safely inducing labor.
BernAges 18–60 - NCT07307365Recruiting
Test for early labor risk in pregnant women
This trial tests a new kit (PremaSure) to see if it can accurately predict which pregnant women with early labor symptoms are at risk of delivering prematurely. It aims to help doctors make better decisions about monitoring and care.
Lausanne, Canton of VaudAges 18 years+ - NCT06980025RecruitingPhase 3
Aspirin dose trial to prevent preterm birth
This study tests if a higher dose of aspirin can help prevent another early delivery in women who have had a preterm birth before. If you qualify, you would take either a standard or escalated dose of aspirin during your current pregnancy.
Birmingham, AlabamaAges 14 years+ - NCT06945809Recruiting
Sealing distal tears after aortic dissection repair
This trial tests a new device (WeFlow-EndoPatch) to seal small tears in the aorta after previous dissection repair. It may be an option if you have 1 or 2 small tears in your descending aorta and are generally healthy enough for a catheter procedure.
Beijing, Beijing MunicipalityAges 18–80 - NCT06776783RecruitingPhase 3
Testing a new surfactant for breathing problems in premature babies
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
Little Rock, ArkansasAges 1 hour–1 day - NCT05698966Recruiting
Low-dose steroid shot to help late preterm baby lungs
This study tests whether a low dose of a steroid medicine given to pregnant people late in pregnancy can help a baby’s lungs if delivery happens early. If you’re due for late-preterm delivery soon, the trial may help reduce breathing problems in the newborn.
AfulaAges 18–45 - NCT06268431Recruiting
Trial of oxytocin rest to reduce c-section
This trial tests whether taking a break from oxytocin (a medicine used to strengthen contractions) can help reduce the chance of needing a C-section. It is for women whose labor has slowed down despite oxytocin.
Newark, DelawareAges 18–55 - NCT06604325Recruiting
Tranexamic acid to reduce blood loss during c-section
This trial tests whether giving a medicine called tranexamic acid before a cesarean section (c-section) can help reduce the amount of blood loss during the surgery. It may be an option for women having either a planned or unplanned c-section.
Fatehpur, Uttar PradeshAges 18–45 - NCT07674173Recruiting
Registry study of Minos stent-graft for abdominal aortic aneurysm
This study tracks the long-term safety and effectiveness of the Minos stent-graft system in treating abdominal aortic aneurysms. It collects data from patients across Europe and Asia to see how well the device works over five years.
Lanzhou, GansuAges 18 years+ - NCT07585916Recruiting
Prenatal Yoga for Pregnant Women
This study tests whether doing yoga during pregnancy is safe and helpful for expecting mothers. Researchers want to see if prenatal yoga can improve pregnancy outcomes and how mothers feel during pregnancy.
Bartın, BartınAges 18 years+ - NCT07570121RecruitingPhase 1
How Caffeine Moves Through Pregnancy and to the Baby
This study looks at how caffeine is absorbed and transferred to a baby during pregnancy in women at risk of early delivery. Researchers hope to understand safe caffeine use in this situation and potentially help prevent complications.
Indianapolis, IndianaAges 18 years+ - NCT07517796RecruitingPhase 4
IV Papaverine to Help Induce Labor in Pregnancies with Broken Water
This study tests whether an IV medication called papaverine can help induce labor in pregnant people at term (37+ weeks) whose water has broken but labor hasn't started yet. The goal is to see if this medication makes labor start naturally and reduces the need for cesarean delivery.
Nahariya, IsraelAges 18–45 - NCT07428317Recruiting
Lubricant gel to shorten pushing during labor
This study tests if using a lubricant gel during the pushing stage of labor can shorten the time it takes for a baby to be born vaginally. If you are healthy and have a low-risk pregnancy, this may help make your delivery faster and easier.
Tegucigalpa, Francisco Morazán DepartmentAges 18–49
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Common questions
- Are there clinical trials for perineal laceration, tear, or rupture during delivery?
- Yes. Clin2 currently lists 34 recruiting perineal laceration, tear, or rupture during delivery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perineal laceration, tear, or rupture during delivery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perineal laceration, tear, or rupture during delivery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.