Clinical trials · Chicago, IL
Peripheral Arterial Disease clinical trials in Chicago
We’re tracking 19 recruiting peripheral arterial disease studies with a site in or near Chicago — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Chicago, IllinoisAges 18 years+ - NCT04794530RecruitingPhase 3
Cocoa extract trial for walking problems in blocked leg arteries
This Phase 3 study tests whether cocoa extract (cocoa flavanols) can improve walking ability and circulation in people with peripheral artery disease (PAD). It may help people who have PAD-related walking limits and can safely avoid competing cocoa sources and caffeine.
Chicago, IllinoisAges 55 years+ - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
Chicago, IllinoisAges 18 years+ - NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries
This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.
Chicago, IllinoisAges 50 years+ - NCT06399900Recruiting
Light therapy plus exercise for better walking with PAD
This study tests whether adding light therapy to a walking program helps people with peripheral artery disease (PAD) walk further and feel better. You'll receive either light therapy or a placebo light while doing a supervised exercise program.
Chicago, IllinoisAges 50 years+ - NCT06399809RecruitingPhase 2
Fisetin for better walking in peripheral artery disease
This study tests whether a supplement called fisetin can help reduce leg pain and improve walking ability in people with peripheral artery disease (PAD). If you have PAD and are 50 or older, you may be able to join and help see if fisetin can make walking easier.
Chicago, IllinoisAges 50 years+ - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Chicago, IllinoisAges 30–60 - NCT06686121RecruitingPhase 3
Improving walking after leg artery surgery for PAD
This trial tests whether drinking beetroot juice and doing home-based exercise can improve walking ability after you've had a procedure to open up blocked leg arteries. It's for people who are ready to start a walking program and want to avoid surgery.
Chicago, IllinoisAges 18 years+ - NCT06032065RecruitingPhase 3
Exercise for peripheral artery disease
This trial tests whether a home-based exercise program is as effective as supervised exercise for improving walking ability in people with peripheral artery disease (PAD). You will be randomly assigned to one of two exercise groups, and you may be asked to drink beetroot juice as part of the study.
Chicago, IllinoisAges 50 years+ - NCT06657976RecruitingPhase 2
Beetroot juice and exercise for PAD
This study tests whether beetroot juice, which contains natural nitrates that help blood vessels relax, combined with exercise, can improve walking ability in people with peripheral artery disease (PAD). You might be able to join if you have PAD, can walk without a walker, and are willing to avoid beet products for a while.
Chicago, IllinoisAges 50 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Chicago, IllinoisAges Any age - NCT01904851Recruiting
Registry for leg artery procedures and their outcomes
This study collects information about people who had a procedure to improve blood flow in certain leg arteries. It helps researchers understand which treatments work best and what outcomes to expect.
Chicago, IllinoisAges Any age - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Chicago, IllinoisAges 18–95 - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Maywood, IllinoisAges 18–80 - NCT07062471Recruiting
Shockwave balloon treatment for hardened carotid arteries before stenting
This study tests a special balloon that uses sound waves to break up calcium buildup in the carotid artery (the main artery in your neck) before placing a stent. It's for people who are at high risk for traditional surgery and have heavy calcium deposits in their artery.
Park Ridge, IllinoisAges 18 years+ - NCT07223593RecruitingPhase 3
Orforglipron for peripheral artery disease with leg pain
This trial tests a new oral medication called orforglipron to see if it can improve walking distance in people with peripheral artery disease (PAD) who have leg pain when walking. It may be a good option if you have PAD and your walking is limited by leg cramping, not other health issues.
Hammond, IndianaAges 18 years+ - NCT05868161Recruiting
Registry for patients treated with a thrombectomy device
This registry collects past treatment information from people who had a clot procedure using the Pounce Thrombectomy System. It helps researchers understand how this device is used in real-world care and what outcomes may look like.
Munster, IndianaAges 18 years+ - NCT07318610RecruitingPhase 3
Study of a new blood thinner in people with leg artery disease
This trial tests if a new blood-thinning drug (factor XI inhibitor) can prevent serious heart and leg problems in people who recently had a leg artery procedure. It compares the new drug to standard care for up to 3 years.
Munster, IndianaAges 18 years+
Hear when a new Peripheral Arterial Disease trial opens near Chicago, IL
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Peripheral Arterial Disease trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting peripheral arterial disease studies listed above.
- Northwestern University · 8 studies
- University of Chicago · 8 studies
- Rush University Medical Center · 2 studies
- Advocate Health
- Advocate Lutheran General Hospital
- ASHA Clinical Research
- Cardiovascular Research of Northwest Indiana LLC
- Loyola University Chicago
What taking part in a peripheral arterial disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting peripheral arterial disease studies in Illinois.
Common questions
- Are there peripheral arterial disease clinical trials near Chicago?
- Yes. We're currently tracking 19 recruiting peripheral arterial disease studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a peripheral arterial disease study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a peripheral arterial disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New peripheral arterial disease studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.