Clinical trials
Peripheral Vascular Diseases clinical trials
Below are recruiting peripheral vascular diseases clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112171Recruiting
Comparing treatments for leg artery blockages with severe calcium
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
Leipzig, SaxonyAges 18 years+ - NCT06237621Recruiting
Using a special camera to check leg circulation
This study tests a special camera (SnapshotNIR) that takes pictures of blood flow in your legs while you move them into different positions. It may help doctors better understand your circulation and diagnose peripheral artery disease (PAD) without needles or dye.
San Antonio, TexasAges 35–99 - NCT06260488Recruiting
Using AI to study leg arteries before amputation
This trial uses artificial intelligence to analyze CT scans and microscope images of the main leg artery. It aims to improve understanding of artery structure. Participation is only for patients who are already scheduled for a leg amputation as part of their medical care.
Strasbourg, Bas-RhinAges 18 years+ - NCT06263322Recruiting
Recovery tracking after leg artery surgery
This study tests a mobile app to track your recovery after surgery for severe leg artery disease. The goal is to see if using the app helps improve your recovery and quality of life.
Gainesville, FloridaAges 60–100 - NCT06409949Recruiting
MitoQ for leg pain from blocked arteries
This study tests whether MitoQ, a supplement that protects cells, can improve leg pain and walking ability in people with peripheral artery disease. It aims to see if it helps the tiny blood vessels and muscle fibers in the leg.
Omaha, NebraskaAges 21 years+ - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT02842424RecruitingPhase 4
Ramipril for walking pain from blocked leg arteries
This study tests whether ramipril (a blood-pressure medicine) can improve leg muscle problems linked to poor blood flow in people with chronic claudication—pain that limits walking. It’s mainly looking at changes related to oxidative stress and muscle scarring (fibrosis).
Omaha, NebraskaAges 18–90 - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT06325800Recruiting
Heart and blood vessel health registry
This study collects information from people at risk for heart disease, stroke, or kidney problems to better understand how to prevent these conditions. If you join, you'll be helping doctors learn more about how to keep blood vessels healthy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06878482RecruitingPhase 4
Botulinum toxin injection for severe leg artery disease
This trial tests whether a single injection of botulinum toxin (a muscle-relaxing substance) into the leg can improve blood flow and help heal wounds in people with severe blocked leg arteries who cannot have standard procedures like angioplasty.
Yongin-si, Gyeonggi-doAges 20 years+ - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75 - NCT03938155Recruiting
Risk check program for older women in Manitoba
This trial looks at how well a health risk assessment can identify heart and blood-vessel problems in women 55 and older. It may help doctors target prevention earlier, which could lower the chance of serious events.
Winnipeg, ManitobaAges 55 years+ - NCT07265544Recruiting
Liver disease study using advanced tissue analysis
This study uses advanced techniques to analyze liver tissue samples from people with various liver conditions. It aims to better understand how liver diseases develop and progress, which may help improve future treatments.
Guangzhou, GuangdongAges Any age - NCT07211035Recruiting
Study of a device to help create a working dialysis access
This study tests a device that widens your vein before creating the connection used for dialysis. The goal is to help the access mature faster and work better for your treatments.
Boston, MassachusettsAges 18 years+ - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+
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Common questions
- Are there clinical trials for peripheral vascular diseases?
- Yes. Clin2 currently lists 112 recruiting peripheral vascular diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral vascular diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral vascular diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.