Clinical trials
Peripheral Vascular Diseases clinical trials
Below are recruiting peripheral vascular diseases clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07588256Recruiting
AI Digital Health Platform for High Blood Pressure and Related Conditions
This study uses artificial intelligence and a digital health app to help manage high blood pressure, high cholesterol, diabetes, kidney disease, and heart disease. It aims to help people track their health at home and receive better care recommendations through technology.
New Taipei CityAges Any age - NCT05802706Recruiting
Study of artery plaque tissue during surgery
This study looks at artery plaque tissue removed during a routine operation (endarterectomy) to better understand diseased vessel changes. You may be able to join if plaque tissue is part of your planned surgery and you can consent.
Limerick, LimerickAges 18 years+ - NCT02748226Recruiting
Study of artery procedures for leg artery disease outcomes
This study looks at results of a minimally invasive procedure done inside blood vessels (endovascular therapy) for people with painful or worsening leg artery disease. It uses both past (retrospective) and future (prospective) patient information to better understand outcomes.
SeoulAges 20 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age - NCT07556497Recruiting
Blood cells and inflammation in diabetic heart disease
This study looks at why people with type 2 diabetes develop heart problems. Researchers will examine special cells in your blood and inflammation markers to better understand these complications.
DohaAges 18 years+ - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30 - NCT06860724Recruiting
Stress and blood vessel health study for adults 18-55
This study looks at how daily stress affects blood vessel function in healthy adults and those with depression. It aims to find links between emotions and physical health.
Newark, DelawareAges 18–55 - NCT05967728Enrolling by invitationPhase 2
Testing remote arm conditioning to protect the brain in stroke
This Phase 2 study tests whether a simple remote method that briefly reduces blood flow in the arm (called ischemic conditioning) can help people with brain small-vessel disease or an acute ischemic stroke. Participants are monitored by phone and, for stroke patients, through a Mobile Stroke Unit.
Calgary, AlbertaAges 55 years+ - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT06237621Recruiting
Using a special camera to check leg circulation
This study tests a special camera (SnapshotNIR) that takes pictures of blood flow in your legs while you move them into different positions. It may help doctors better understand your circulation and diagnose peripheral artery disease (PAD) without needles or dye.
San Antonio, TexasAges 35–99 - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT06260488Recruiting
Using AI to study leg arteries before amputation
This trial uses artificial intelligence to analyze CT scans and microscope images of the main leg artery. It aims to improve understanding of artery structure. Participation is only for patients who are already scheduled for a leg amputation as part of their medical care.
Strasbourg, Bas-RhinAges 18 years+ - NCT02842424RecruitingPhase 4
Ramipril for walking pain from blocked leg arteries
This study tests whether ramipril (a blood-pressure medicine) can improve leg muscle problems linked to poor blood flow in people with chronic claudication—pain that limits walking. It’s mainly looking at changes related to oxidative stress and muscle scarring (fibrosis).
Omaha, NebraskaAges 18–90 - NCT06263322Recruiting
Recovery tracking after leg artery surgery
This study tests a mobile app to track your recovery after surgery for severe leg artery disease. The goal is to see if using the app helps improve your recovery and quality of life.
Gainesville, FloridaAges 60–100 - NCT04433572RecruitingPhase 3
Temsirolimus treatment to improve below-knee artery procedures
This trial studies whether delivering a medicine called temsirolimus directly into the artery during a below-knee revascularization procedure can improve blood flow and outcomes. It may help people with severe leg artery disease who have symptoms like pain while walking or threatened limb tissue loss.
Houma, LouisianaAges 18 years+ - NCT06657976RecruitingPhase 2
Beetroot juice and exercise for PAD
This study tests whether beetroot juice, which contains natural nitrates that help blood vessels relax, combined with exercise, can improve walking ability in people with peripheral artery disease (PAD). You might be able to join if you have PAD, can walk without a walker, and are willing to avoid beet products for a while.
Chicago, IllinoisAges 50 years+ - NCT06409949Recruiting
MitoQ for leg pain from blocked arteries
This study tests whether MitoQ, a supplement that protects cells, can improve leg pain and walking ability in people with peripheral artery disease. It aims to see if it helps the tiny blood vessels and muscle fibers in the leg.
Omaha, NebraskaAges 21 years+ - NCT06112171Recruiting
Comparing treatments for leg artery blockages with severe calcium
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
Leipzig, SaxonyAges 18 years+ - NCT05624125Recruiting
Beetroot juice study for circulation problems in leg arteries
This trial tests whether drinking beetroot juice can improve how well people with peripheral artery disease (PAD) can function and walk. It’s looking at circulation-related measurements in the legs and how you do on walking tests.
Chicago, IllinoisAges 50 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
La Jolla, CaliforniaAges 18–95 - NCT04794530RecruitingPhase 3
Cocoa extract trial for walking problems in blocked leg arteries
This Phase 3 study tests whether cocoa extract (cocoa flavanols) can improve walking ability and circulation in people with peripheral artery disease (PAD). It may help people who have PAD-related walking limits and can safely avoid competing cocoa sources and caffeine.
Chicago, IllinoisAges 55 years+ - NCT03791970Recruiting
Compare stent post-dilation using drug balloon or regular balloon
This study looks at whether using a drug-coated balloon (DCB) versus a regular balloon (POBA) right after placing a stent works better in artery blockages in the thigh/knee area. It may help improve blood flow and reduce the chance the artery narrows again.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06325800Recruiting
Heart and blood vessel health registry
This study collects information from people at risk for heart disease, stroke, or kidney problems to better understand how to prevent these conditions. If you join, you'll be helping doctors learn more about how to keep blood vessels healthy.
Santiago de Compostela, A CoruñaAges 18 years+
Hear when a new Peripheral Vascular Diseases trial opens
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Common questions
- Are there clinical trials for peripheral vascular diseases?
- Yes. Clin2 currently lists 103 recruiting peripheral vascular diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral vascular diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral vascular diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.