Clinical trials · Philadelphia, PA
Persistent Atrial Fibrillation clinical trials in Philadelphia
We’re tracking 14 recruiting persistent atrial fibrillation studies with a site in or near Philadelphia — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06455098Recruiting
Pulsed field ablation for paroxysmal atrial fibrillation
This study tests a new procedure called pulsed field ablation using a special catheter to treat paroxysmal atrial fibrillation (AF), a type of heart rhythm problem that comes and goes. It may be an option for people whose AF hasn't been controlled well with medication.
Philadelphia, PennsylvaniaAges 18–80 - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Philadelphia, PennsylvaniaAges 18–100 - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04088071Recruiting
Ablation for heart rhythm problems using a specific technology
This study looks at how well catheter ablation works for treating certain heart rhythm disorders (like atrial fibrillation or ventricular arrhythmias) using a specific brand of catheters. The aim is to gather real-world data to better understand the procedure's outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Camden, New JerseyAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Wynnewood, PennsylvaniaAges 18 years+ - NCT06735534Recruiting
Repeat ablation for persistent atrial fibrillation with pulsed field
This trial tests a newer type of ablation (pulsed field ablation) for people with persistent atrial fibrillation who have already had one ablation. The goal is to see if it can fix the heart rhythm problem again.
Marlton, New JerseyAges 18 years+ - NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Doylestown, PennsylvaniaAges 18 years+
Hear when a new Persistent Atrial Fibrillation trial opens near Philadelphia, PA
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Persistent Atrial Fibrillation trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting persistent atrial fibrillation studies listed above.
- University of Pennsylvania · 7 studies
- Thomas Jefferson University Hospital · 3 studies
- Capital Health
- Cardiovascular Associates of the Delaware Valley
- Cooper University Health Care
- Doylestown Health Cardiology
- Jefferson Abington Hospital
- Lankenau Medical Center
What taking part in a persistent atrial fibrillation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting persistent atrial fibrillation studies in Pennsylvania.
Common questions
- Are there persistent atrial fibrillation clinical trials near Philadelphia?
- Yes. We're currently tracking 14 recruiting persistent atrial fibrillation studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a persistent atrial fibrillation study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a persistent atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New persistent atrial fibrillation studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.