Clinical trials
Personality clinical trials
Below are recruiting personality clinical trials, each written for real people, not researchers. We’re tracking 831 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04852744Recruiting
Brain scan study in teens with borderline and/or PTSD
This study uses brain imaging (MRI) to compare brain patterns in teens with borderline personality disorder and those with PTSD, as well as teens without these mental health diagnoses. It may help researchers understand what brain differences go along with these conditions and how they relate to each other.
CaenAges 13–18 - NCT06726187Recruiting
Autism and personality in adults
This study looks at personality traits and disorders in adults with autism. You and someone who knows you well will answer questions to help researchers understand how autism and personality relate.
RotterdamAges 18 years+ - NCT06712745RecruitingEarly Phase 1
Personalized lung cancer radiation therapy study
This trial tests a new approach to radiation therapy for central lung cancers, giving high doses in very short bursts to see if it's safe and effective. It may be an option for people whose tumors are not too large and are in a specific central location.
Dallas, TexasAges 18 years+ - NCT06683014RecruitingPhase 2
MDMA study for borderline personality disorder
This trial tests if a single dose of MDMA, given under supervision, can help people with borderline personality disorder (BPD). You will stay overnight after the session and be followed up for two weeks.
New Haven, ConnecticutAges 18–60 - NCT06675461Enrolling by invitation
Brief talk therapy for suicidal patients with borderline personality disorder
This trial tests a short talk therapy for people with borderline personality disorder who come to the emergency department after hurting themselves or thinking about suicide. The goal is to see if this brief help can ease suicidal thoughts and keep you safer.
Toronto, OntarioAges 16 years+ - NCT02097706RecruitingPhase 2
Drug study for borderline personality disorder
This Phase 2 study tests a new medicine for people with borderline personality disorder (BPD) to see if it can improve symptoms. You may qualify if you have a confirmed BPD diagnosis and meet safety and medication rules.
Melbourne, VictoriaAges 18–65 - NCT06653738RecruitingPhase 3
Testing empagliflozin and diet advice for kidney stone prevention
This trial tests if a medication called empagliflozin, combined with personalized diet advice, can help prevent kidney stones from coming back. It may be an option if you've had two or more kidney stone events in the last 10 years and your stones were mostly calcium-based.
AmiensAges 18 years+ - NCT06626061Enrolling by invitation
Online or in-person program to reduce healthcare worker burnout
This study tests a program (CBSM) to help reduce burnout and stress for healthcare workers. It compares attending sessions in person versus online, to see which works better for you.
Chambéry, FranceAges Any age - NCT06591754Enrolling by invitation
Personality disorder therapy study at Karolinska
This trial tests a special talk therapy (ISTDP) for people with personality disorders. It aims to see if the therapy helps in a psychiatric clinic setting.
StockholmAges 18 years+ - NCT06585085Recruiting
Physical activity and sitting study for pregnant women
This study tests whether a physical activity program during pregnancy can help reduce sitting time and improve health for expecting mothers. You would be randomly placed in either the exercise program or your usual care, and your activity levels would be tracked.
Clermont-FerrandAges 18 years+ - NCT06572423Recruiting
Personalized focused radiation for head and neck cancer
This trial tests a personalized, very precise radiation treatment (called PULS-Pal) for head and neck cancer that cannot be cured with standard therapies. It aims to shrink tumors and help with symptoms while limiting side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT06563466Recruiting
Pegasus: Better treatment for emotional instability
This study tests a new way to treat emotionally unstable personality disorder (also called borderline personality disorder) by including family or close friends in therapy. It aims to see if this approach improves how patients feel and function.
CopenhagenAges 18 years+ - NCT06533176Recruiting
Personalized brain stimulation after stroke
This study tests a new way to apply brain stimulation called TMS while watching your brain activity in real time, tailored to your personal brain state. It is for people who still have arm or hand weakness at least 6 months after a stroke.
Iowa City, IowaAges 18 years+ - NCT06529822RecruitingPhase 1
Personalized cancer vaccine for solid tumors with residual disease
This trial tests a personalized cancer vaccine designed to help your immune system fight any remaining cancer cells after surgery. It is for people with certain solid tumors—like bladder, stomach, melanoma, or lung cancer—that show signs of disease through a blood test.
Orlando, FloridaAges 18 years+ - NCT06506435Recruiting
Radiation therapy education using virtual reality
This study tests whether watching a virtual reality video before radiation therapy helps you understand the treatment better. It is for people with cancer who are starting radiation therapy at the University of Miami.
Miami, FloridaAges 18 years+ - NCT06505226Recruiting
Music mindfulness study for anxiety and depression
This study tests a music-based mindfulness program to help people with anxiety or depression. It compares the program to a wait list to see if it eases symptoms.
New Haven, ConnecticutAges 18–65 - NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT06458933RecruitingPhase 2
Couples therapy for borderline personality disorder
This study tests talk therapy for couples where one person has borderline personality disorder (BPD). It aims to see if the therapy helps improve symptoms and relationship quality.
Toronto, CaliforniaAges 19 years+ - NCT06446765RecruitingPhase 2
Mindfulness and brain feedback to boost BPD therapy
This study tests whether combining mindfulness training with brain scan feedback (neurofeedback) can improve the benefits of regular talk therapy for adults with borderline personality disorder. It takes place at Yale University.
New Haven, ConnecticutAges 18–60 - NCT06434376Enrolling by invitationEarly Phase 1
Personalized immune therapy for ctDNA-positive colorectal cancer
This trial tests a personalized immune therapy (like a custom vaccine) for people with colorectal cancer that has a positive ctDNA MRD test after surgery. It aims to use the body's own immune system to target any remaining cancer cells and prevent the cancer from coming back.
Wenzhou, ZhejiangAges 18–80 - NCT06309316Recruiting
Person-centered care for Graves' disease
This trial tests if a person-centered care approach improves well-being for people newly diagnosed with Graves' disease. You may receive extra support focused on your personal needs and goals.
GothenburgAges 18–65 - NCT06298721Recruiting
Personalized care to improve knee replacement satisfaction
This study tests a personalized approach to knee replacement surgery designed for people who are at higher risk of being dissatisfied after the procedure. The goal is to see if tailoring care based on patient-reported outcomes can improve satisfaction.
Cleveland, OhioAges 18–80 - NCT03994510Recruiting
Study of shame in borderline personality disorder
This study looks at how people with borderline personality disorder experience shame and how that relates to symptoms and behavior. The goal is to better understand shame so future treatments can be more targeted.
Montpellier, HéraultAges 18 years+ - NCT06208605Recruiting
Personalized eating disorder treatment study
This study is testing a new way to personalize treatment for people with an active eating disorder (except ARFID). It aims to find what works best for you.
Louisville, KentuckyAges 18–65
Hear when a new Personality trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for personality?
- Yes. Clin2 currently lists 831 recruiting personality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a personality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a personality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.