Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,955 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06909890Recruiting
Chios mastic water for stomach discomfort
This study tests whether a special water made from Chios mastic can help with dyspepsia (ongoing indigestion or stomach discomfort). It's designed for people who don't have other serious health conditions.
Kallithea, AtticaAges 30–60 - NCT07585474Enrolling by invitation
Gut Health During Long Travel for Football Players
This study looks at how long airplane trips affect the gut bacteria in professional male football players. Researchers will track changes in your digestive system during pre-season travel to understand if travel impacts your gut health.
Nashville, TennesseeAges 18–40 - NCT06900972Enrolling by invitationPhase 3
Comparing fluids' effect on heart function
This trial compares two types of IV fluids (colloids and crystalloids) to see how they affect heart function. It is open to healthy adults who are not pregnant and have no known medical problems.
Monastir, TunisiaAges 18–60 - NCT06937944RecruitingPhase 3
New Botox-like injection for frown lines
This study tests a new botulinum toxin injection (similar to Botox) to see how well it smooths moderate to severe frown lines between the eyebrows. The treatment is given as a single injection and may help soften those lines for several months.
Beijing, Beijing MunicipalityAges 18–65 - NCT06900452Recruiting
Pistachio breakfast and brain function in older adults
This study tests whether eating a pistachio-rich breakfast can improve memory and thinking in healthy older adults. If you qualify, you'll eat special breakfast meals and do some computer-based thinking tasks to measure how your brain performs.
Reading, BerkshireAges 65–80 - NCT06793891Recruiting
Ashwagandha extract for stress relief in women
This trial tests whether an ashwagandha supplement can help reduce high stress levels in women. If you are a woman feeling very stressed and meet the other requirements, this study might offer a natural way to manage stress.
Huntsville, AlabamaAges 30–59 - NCT06876129RecruitingPhase 1
Adding D-serine to TMS for depression
This trial tests whether adding a medication called D-serine to a brain stimulation treatment (TMS) helps improve depression. It’s for adults with major depression who are already getting TMS therapy.
Belmont, MassachusettsAges 18–80 - NCT06247046RecruitingPhase 3
Probiotic powder for IBS-D (SK08) trial
This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.
Wuxi, JiangsuAges 18–70 - NCT07157787RecruitingPhase 2
Testing a new drug for primary membranous nephropathy
This trial tests a new drug called ALXN1920 for adults with primary membranous nephropathy (PMN), a kidney disease where the immune system attacks the kidneys. It is for people at high risk of their disease getting worse, and it compares the new drug added to standard care versus standard care alone.
Loma Linda, CaliforniaAges 18–75 - NCT03947450RecruitingPhase 2
Injection of your own skin cells into below-knee amputation site
This Phase 2 study tests whether injecting a patient’s own fibroblast cells (skin-support cells) into the wound area after a below-knee amputation can help the stump skin heal and work better. It’s intended for people who already have (or are close to having) a prosthetic fitting.
Baltimore, MarylandAges 18–65 - NCT05555589RecruitingPhase 3
RGN-259 eye drops for neurotrophic keratopathy with persistent corneal defects
This Phase 3 trial tests whether a 0.1% RGN-259 eye drop can safely improve a stubborn corneal wound in adults with neurotrophic keratopathy (nerve-related corneal healing problems). You may qualify if you still have an eye surface defect after at least a week of standard treatments, and you meet specific measurements for corneal sensitivity and vision.
Laguna Hills, CaliforniaAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT06819254RecruitingPhase 4
Fisetin for fatigue in older cancer survivors
This study tests whether a natural compound called fisetin can reduce fatigue in people aged 60+ who have completed cancer treatment. If you still feel tired often, this pill-based treatment might help you regain energy.
Winston-Salem, North CarolinaAges 65 years+ - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT06804980RecruitingPhase 4
Rosuvastatin Tolerance for People with Statin Side Effects
This trial tests a low dose of rosuvastatin (a common statin) in people who have had trouble with statins before. The goal is to see if your body can tolerate this specific dose again, which could help lower your cholesterol without the past side effects.
Minneapolis, MinnesotaAges 21 years+ - NCT07400965RecruitingPhase 2
Testing a new eye drop for eyelid inflammation caused by tiny mites
This trial tests an investigational eye drop (GLK-321) to see if it safely and effectively treats Demodex blepharitis, an eyelid inflammation caused by tiny mites. It may help people who have signs of this condition and good enough vision.
Newport Beach, CaliforniaAges 18 years+ - NCT06771323RecruitingPhase 2
Adding valbenazine to botox for neck muscle spasms
This study tests if adding a daily pill (valbenazine) to regular botox injections can better reduce neck muscle spasms. It helps people whose botox works but may not be enough.
Richmond, VirginiaAges 18–75 - NCT06118281RecruitingPhase 3
Testing ziltivekimab after a heart attack
This study tests a new drug called ziltivekimab to see if it helps people who have recently had a heart attack. The drug is given as an injection and compared to a placebo (a shot with no active medicine).
Alexander City, AlabamaAges 18 years+ - NCT07382167RecruitingPhase 3
Study of Tenapanor for Chronic Constipation in Adults
This study tests an investigational drug called tenapanor for people with chronic idiopathic constipation (constipation with no clear cause). It aims to see if the drug can safely improve bowel movements in adults.
Foley, AlabamaAges 18–80 - NCT06625060RecruitingPhase 2
Study of IPN10200 for preventing migraine in adults
This trial tests a new medicine called IPN10200 to see if it can prevent episodic or chronic migraine. It is for adults who have had migraine for at least a year and have tried at least one preventive treatment before.
Birmingham, AlabamaAges 18–80 - NCT06734975RecruitingPhase 2
Nerve block for better recovery after vocal cord surgery
This study tests if a nerve block can help reduce pain and improve recovery after surgery to remove a noncancerous growth on the vocal cords. Participants will be randomly assigned to receive either the nerve block or standard care.
Newark, New JerseyAges 18 years+ - NCT07430397RecruitingPhase 1
Safety study of CITY-FXI in healthy adults and those with clotting risks
This trial tests a new medicine, CITY-FXI, to see if it is safe and how it works in the body. It is for healthy adults and also for adults with specific genetic conditions (Factor V Leiden or Prothrombin G20210A mutation) that increase the risk of blood clots.
LondonAges 18–60 - NCT07427797RecruitingPhase 3
Study of a treatment for frown lines between the eyebrows
This study tests a new medicine (IPN10200) to see how well it works and how safe it is for reducing moderate to severe frown lines between the eyebrows in adults. If you are unhappy with the appearance of these lines, this trial may help.
Birmingham, AlabamaAges 18–80 - NCT07432490RecruitingPhase 2
Fucose supplement trial for GLUT1 deficiency
This trial tests whether taking fucose (a type of sugar) can help people with GLUT1 deficiency syndrome, a rare genetic condition that affects how the brain gets energy. If you have ataxia (trouble with balance or coordination) and meet other criteria, this study may be an option for you.
Portland, OregonAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,955 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.