Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,240 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07031128RecruitingPhase 4
AKG supplement trial for older heart bypass patients
This trial tests whether a supplement called alpha ketoglutarate (AKG) can help older adults recover better after heart bypass surgery. If you are 50 or older and scheduled for elective bypass surgery, you may be able to join.
Singapore, SingaporeAges 50 years+ - NCT07046572Recruiting
Pain relief for IUD insertion or endometrial biopsy
This trial tests if a pain-relief medication called methoxyflurane can help women who haven't had children before feel less pain during IUD insertion or a uterine biopsy. If you're getting one of these procedures and are not currently breastfeeding or using strong painkillers, this study might be for you.
Toronto, OntarioAges 18–65 - NCT07224360RecruitingPhase 2
Safety of a new drug for sickle cell pain
This study tests a new medicine called anumigilimab to see if it is safe for people with sickle cell disease. The study focuses on those who have had pain crises recently, to help manage and prevent them.
Little Rock, ArkansasAges 18 years+ - NCT07620938RecruitingPhase 2
TJ0113 capsule for treating muscle loss in older adults
This study tests a new capsule called TJ0113 to see if it can help older adults with sarcopenia (muscle loss) improve their muscle strength and physical function. It's a phase 2 study, meaning the drug is being tested for safety and effectiveness.
Hangzhou, ZhejiangAges 60 years+ - NCT07747909Recruiting
Orlistat for metabolic and hormonal health in PCOS
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Abbottābād, Khyber PakhtunkhwaAges 18–45 - NCT07595458RecruitingPhase 1
Safety Study of JST-018 Immune Treatment in Healthy Adults
This is a first-in-human safety study testing a new experimental immune therapy called JST-018. Researchers want to see how safe it is, how well your body tolerates it, and how your body processes it when given as an injection.
Las Vegas, NevadaAges 18–55 - NCT06788756RecruitingPhase 2/Phase 3
Testing L-Annamycin plus Cytarabine for relapsed AML
This trial tests whether the combination of two chemotherapy drugs, L-Annamycin and Cytarabine, can help adults whose acute myeloid leukemia (AML) has come back or not responded to one prior treatment. The goal is to see if this combination can lead to remission.
Birmingham, AlabamaAges 18–80 - NCT07409922RecruitingPhase 1
Testing KR23343 in healthy volunteers
This study tests a new medicine, KR23343, in healthy adults to see how the body handles it at different doses. It helps find the right dose and check for any early side effects.
ShanghaiAges 18–45 - NCT07341386RecruitingPhase 4
Preventing herpes outbreaks in autoimmune rheumatic diseases
This trial tests whether a medicine called acyclovir can prevent herpes simplex outbreaks in people who also have an autoimmune rheumatic disease. It may help reduce the number of painful cold sores or genital herpes episodes you experience.
São Paulo, São PauloAges 12 years+ - NCT06674109RecruitingPhase 4
Testing a diabetes drug for gout prevention
This study tests if a type 2 diabetes medication (SGLT2 inhibitor) can help people with frequent gout flares. It aims to lower uric acid levels and reduce flare-ups.
Boston, MassachusettsAges 18–80 - NCT07674667RecruitingPhase 1/Phase 2
Testing a treatment to restore UNC13A function in ALS
This trial tests a new treatment aimed at restoring the function of a gene called UNC13A in people with ALS. It involves multiple clinic visits, MRI scans, and spinal taps to see if the treatment is safe and may slow the disease.
MunichAges 18–75 - NCT07729839RecruitingPhase 1
Study of ADB116 injection for healthy volunteers
This trial tests a new medicine called ADB116 in healthy people to see how safe it is and how the body processes it. The results will help decide the right dose for future studies.
Guangzhou, GuangdongAges 18–45 - NCT05435547RecruitingPhase 4
Pre-surgery steroid medicine for autoimmune thyroid disease
This trial tests whether taking corticosteroids (anti-inflammatory medicines) before thyroid surgery is safe and helpful for people with autoimmune thyroid disease. It focuses on Graves’ or Hashimoto’s disease patients who are planning total thyroid removal.
Indianapolis, IndianaAges 18 years+ - NCT07399171RecruitingPhase 2
Testing HT-4253 to prevent Alzheimer's in APOE4 carriers
This trial tests an experimental drug called HT-4253 to see if it can prevent Alzheimer's disease in people who are at higher genetic risk (carry the APOE4 gene) and have early signs of amyloid buildup in the brain. If you qualify, you would take the drug or a placebo and be monitored over time.
Abu Dhabi, Abu Dhabi EmirateAges 50–75 - NCT06224530Recruiting
Testing levetiracetam's effect on brain function in psychosis risk
This trial tests whether a single dose of levetiracetam, a medication that affects brain chemistry, can change brain function and thinking in people at risk for psychosis. The goal is to see if it might help prevent symptoms from worsening.
London, LondonAges 18–40 - NCT07287670RecruitingPhase 2
Testing MTX-474 for diffuse scleroderma
This trial tests an investigational drug called MTX-474 for people with diffuse cutaneous systemic sclerosis (a type of scleroderma that affects the skin and internal organs). The study aims to see if it can help slow or improve skin thickening and other symptoms.
Phoenix, ArizonaAges 18 years+ - NCT05039619RecruitingPhase 2
Obinutuzumab trial for adolescents with active lupus kidney inflammation
This Phase 2 study tests obinutuzumab, a targeted antibody medicine, in teens with active lupus nephritis (inflammation in the kidney). It looks at whether it helps kidney disease and is safe, including how the body handles the drug.
Loma Linda, CaliforniaAges 5–17 - NCT05771675RecruitingEarly Phase 1
Simvastatin trial for symptom relief in pancreatitis
This early-phase study tests whether simvastatin can improve patient-reported symptoms in people with recurrent acute or chronic pancreatitis. It’s meant to see if the medicine is tolerable and helps with how you feel day to day.
Los Angeles, CaliforniaAges 18–75 - NCT06419374RecruitingPhase 3
Testing a new drug for liver scarring from MASH
This trial tests a new drug called pegozafermin to see if it can help people with cirrhosis (scarring) of the liver caused by MASH (a fatty liver disease). If you have cirrhosis and either diabetes or multiple risk factors, this study might be an option for you.
Birmingham, AlabamaAges 18–75 - NCT06318169RecruitingPhase 3
Testing pegozafermin for MASH and liver fibrosis
This trial tests an experimental drug called pegozafermin to see if it can help people with MASH (a fatty liver disease) and liver scarring (fibrosis). It's for people who have moderate-to-advanced scarring but not cirrhosis, and who have not had other serious liver conditions or poorly controlled diabetes.
Birmingham, AlabamaAges 18–80 - NCT07566390RecruitingPhase 1
Testing a new weight-loss medicine in healthy adults
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Glendale, CaliforniaAges 18–55 - NCT07656415RecruitingPhase 3
Study of mitapivat for sickle cell disease patients who need blood transfusions
This study tests whether a daily pill called mitapivat can reduce the number of blood transfusions you need. It is for people with sickle cell disease who have had at least one transfusion in the past year and are not on regular transfusion therapy.
Indianapolis, IndianaAges 12 years+ - NCT07087054RecruitingPhase 3
A daily pill for carcinoid syndrome symptoms
This trial tests an oral daily medication, paltusotine, to reduce flushing and other symptoms of carcinoid syndrome in people with neuroendocrine tumors. It may be an option for those who need treatment and have stable disease.
Gilbert, ArizonaAges 18 years+ - NCT07737665RecruitingPhase 4
Melatonin for better sleep in IBD patients in remission
This study tests whether melatonin (a natural sleep hormone) can improve sleep quality in people with inflammatory bowel disease (IBD) whose disease is quiet (in remission). If you have IBD and trouble sleeping, you may be able to join.
Bangkok Noi, BangkokAges 18 years+
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,240 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.