Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07737054RecruitingEarly Phase 1
Psilocybin therapy for PTSD
This trial tests a type of therapy that uses psilocybin (a safe, natural substance found in certain mushrooms) to help people with PTSD. It combines talk therapy with the medicine to see if it can reduce trauma symptoms.
Tel AvivAges 21–65 - NCT07665502Enrolling by invitation
Smartphone app to boost opioid treatment for women facing violence
This study tests a smartphone app (WINGS+++) to help women who have experienced intimate partner violence and trauma improve their engagement with medication for opioid use disorder (MOUD). The goal is to see if the app makes it easier to start and stay on treatment.
New York, New YorkAges 18 years+ - NCT05194930Recruiting
Insomnia treatment study for Veterans with PTSD symptoms
This study tests treatments to help Veterans who have both PTSD symptoms and trouble sleeping (insomnia). You may be invited to try study procedures to see what helps insomnia and whether it also improves sleep-related well-being.
Sepulveda, CaliforniaAges 18 years+ - NCT05974631Recruiting
Treatments for suicidal Veterans with PTSD
This study tests two types of therapy to help Veterans with PTSD who are struggling with suicidal thoughts and self-harm. It compares a treatment called DBT (Dialectical Behavior Therapy, which helps with emotions) with another called PE (Prolonged Exposure, which helps with trauma).
Minneapolis, MinnesotaAges 18 years+ - NCT07462312Recruiting
Wearable device training for PTSD
This trial tests a training program that uses a wearable device to help you control your body's stress responses. It's designed for people with PTSD who are eligible for military rehabilitation services.
JerusalemAges 18–50 - NCT03803332Recruiting
Therapies for PTSD from military sexual trauma compared for adults
This trial compares two types of talk therapy to treat PTSD caused by military sexual trauma. It aims to see which therapy helps symptoms better and how well people can complete weekly outpatient sessions.
New York, New YorkAges 18–85 - NCT04335487Recruiting
Online therapy program for PTSD symptoms in public safety workers
This study tests an internet-based cognitive-behavioral therapy (an online talk-therapy style program that helps you manage thoughts and feelings) to reduce PTSD symptoms in public safety personnel. You may be able to join if you have PTSD-like symptoms and can safely take part in online treatment.
Regina, SaskatchewanAges 18 years+ - NCT04452500RecruitingPhase 2
Study drug for PTSD symptoms in Veterans
This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.
Tuscaloosa, AlabamaAges 18–69 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT05244564Recruiting
PTSD app treatment comparison: monitor vs AR 3MDR
This trial tests whether two different ways of delivering an “AR 3MDR” PTSD therapy work better than a standard computer monitor approach. You may be eligible if you have PTSD and can do the required walking session on a treadmill safely.
Bethesda, MarylandAges 18 years+ - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT05269459RecruitingPhase 2
CBD for PTSD symptoms in adults
This Phase 2 study tests whether cannabidiol (CBD) can safely reduce PTSD symptoms in adults. You may be eligible if you have a current PTSD diagnosis and can follow the study steps for the full time.
Omaha, NebraskaAges 21–65 - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17 - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT05758987Recruiting
Online therapy for PTSD using a computer program
This trial studies a new blended, computer-assisted version of trauma-focused cognitive behavioral therapy for people with PTSD. It may help reduce PTSD symptoms by delivering structured therapy using a computer and online sessions.
StockholmAges 18 years+ - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT06047691Recruiting
Couples therapy for PTSD in military couples
This study tests whether intensive couples therapy helps military couples dealing with PTSD, compared to a relationship education class. If you are a service member or veteran with PTSD and your partner is willing to join, this trial might offer a way to improve your relationship and PTSD symptoms together.
San Antonio, TexasAges 18 years+ - NCT06048172Recruiting
Trauma therapy for PTSD with a psychotic disorder
This trial tests if prolonged exposure therapy, a common PTSD treatment, can help people who also have a psychotic disorder (like schizophrenia or bipolar with psychosis). The goal is to reduce PTSD symptoms.
HamburgAges 18 years+ - NCT06111976Recruiting
TMS plus reactivation therapy for resistant PTSD
This trial tests if adding a type of brain stimulation (TMS) to a memory reactivation therapy can reduce PTSD symptoms that haven't improved with standard antidepressants. If you have persistent PTSD, this study could offer a new treatment option.
ParisAges 18–65 - NCT06144203Recruiting
Exercise effects on fear learning in PTSD
This study explores whether aerobic exercise helps people with or without PTSD better learn to overcome fear. You will do exercise and have brain scans (MRI) to see how your brain processes fear.
Tuscaloosa, AlabamaAges 18–64
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 292 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.