Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06367764Recruiting
PTSD treatment study for sexual and gender minorities
This study compares different treatments for PTSD specifically designed for people who are sexual or gender minorities. It aims to find which approach works best for this community, and you can join sessions in person or by video.
Palo Alto, CaliforniaAges 18 years+ - NCT06394284RecruitingPhase 3
MDMA therapy for PTSD in male Israeli veterans
This study tests whether MDMA (the drug in Ecstasy) can help male Israeli veterans with PTSD feel better, especially if their symptoms are related to moral injury. It involves therapy sessions and monitoring to see how the drug affects your brain and emotions.
JerusalemAges Any age - NCT06414356RecruitingPhase 4
Ketamine for nerve pain and PTSD in military personnel
This study tests whether ketamine infusions can help with ongoing nerve pain and PTSD symptoms. It's for active-duty service members, veterans, and retirees who have had moderate nerve pain for at least 3 months.
San Antonio, TexasAges 18–70 - NCT06419959Recruiting
NightWare watch for better sleep and heart health in veterans with PTSD
This study tests if a special watch (NightWare) can help veterans with PTSD who have nightmares sleep better and improve heart health. The watch vibrates gently during nightmares to reduce them without waking you up.
Aurora, ColoradoAges 22–88 - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT06464952Recruiting
Prebiotics for PTSD and cirrhosis
This trial tests if a prebiotic supplement can improve gut health and PTSD symptoms in people with cirrhosis and PTSD. It aims to see if changing the gut microbiome can help both conditions.
Richmond, VirginiaAges 18 years+ - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06570213RecruitingEarly Phase 1
Neck injection plus talk therapy for PTSD
This study tests whether a combination of a neck injection (stellate ganglion block) and a talk therapy called Cognitive Processing Therapy helps treat PTSD better than either alone. Participants will get two injections two weeks apart, plus a week of daily therapy sessions.
Chicago, IllinoisAges 18 years+ - NCT06588309Recruiting
Trauma and addiction treatment for PTSD and complex PTSD
This study tests combining addiction treatment with EMDR therapy for people with both a substance use disorder and PTSD or complex PTSD. It aims to see how well the integrated treatment works.
ArnhemAges 18 years+ - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT05746572Enrolling by invitationPhase 2
MDMA-assisted therapy plus exposure therapy for PTSD
This Phase 2 study tests whether MDMA combined with therapy that uses exposure (gradual confronting of trauma memories) can reduce PTSD symptoms. It may help people who meet PTSD criteria, can follow strict safety rules, and can complete medicine-session monitoring.
Atlanta, GeorgiaAges 21–70 - NCT06639061RecruitingPhase 2
Brain stimulation to reduce PTSD flashbacks
This study tests whether a non-invasive brain stimulation technique called TMS can help reduce intrusive memories in people with PTSD. It uses MRI to guide the stimulation, and you will be randomly assigned to receive either active TMS or a placebo-like treatment.
Tel AvivAges 20–65 - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Los Angeles, CaliforniaAges 21–65 - NCT06689254RecruitingPhase 2
Testing mifepristone for hard-to-treat PTSD in Dutch adults
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Amsterdam, North HollandAges 18 years+ - NCT06691347Recruiting
Trauma treatment for adults with PTSD in Norway
This study tests if a type of therapy for trauma (EMDR or trauma-focused therapy) helps people with PTSD. It is for adults in Norway who have not had these treatments before.
Drammen, AkershusAges 18 years+ - NCT06700590Recruiting
Intensive PTSD treatment for first-time patients
This study tests an intensive treatment program for adults with PTSD from multiple traumatic events. It may help if you are seeking treatment for the first time and are currently employed or on sick leave for less than two years.
Diemen, North HollandAges 18 years+ - NCT06705296RecruitingPhase 1
Deep brain stimulation for severe PTSD
This trial tests whether deep brain stimulation, a surgery that uses a small device to send electrical pulses to specific brain areas, can help people with severe PTSD that hasn't improved after trying several treatments. It aims to see if this approach is safe and effective for long-lasting symptoms.
Toronto, OntarioAges 18–70 - NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06806267Recruiting
VR therapy with brain stimulation for PTSD in Ukrainians
This study tests if combining virtual reality therapy with a gentle brain stimulation technique (tDCS) can help treat PTSD symptoms in Ukrainian veterans and civilians. It may offer a new way to process traumatic memories.
BerlinAges 18–75 - NCT06826937Recruiting
Short-term recall therapy for severe PTSD
This study tests a new therapy that uses short-term recall and reprocessing to help people with severe PTSD. It may help you if you have strong PTSD symptoms and are not currently in crisis or have certain other mental health conditions.
BeershebaAges 18–70 - NCT06918899Recruiting
Study on complex PTSD in trauma-exposed children
This study looks at complex PTSD in children and teens (ages 7 to 18) who have been through at least one traumatic event. It aims to better understand what factors are related to this condition.
Istanbul, FatihAges 7–18
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 291 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.