Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT06953687Recruiting
Shared decision making for PTSD treatment in active duty military
This trial tests a shared decision-making approach to help active duty military members with PTSD choose the best treatment for them. You and your doctor will work together to decide on a plan that fits your needs and values.
Fort Hood, TexasAges 18 years+ - NCT06902974RecruitingPhase 2
Psilocybin therapy for PTSD from sexual assault
This trial tests whether psilocybin, a psychedelic drug given in a supportive therapy setting, can help women heal from post-traumatic stress disorder (PTSD) caused by a sexual assault that happened 6 or more months ago. You'll receive the drug during supervised sessions and attend therapy visits to see if it reduces your PTSD symptoms.
Rockville, MarylandAges 18 years+ - NCT05244564Recruiting
PTSD app treatment comparison: monitor vs AR 3MDR
This trial tests whether two different ways of delivering an “AR 3MDR” PTSD therapy work better than a standard computer monitor approach. You may be eligible if you have PTSD and can do the required walking session on a treadmill safely.
Bethesda, MarylandAges 18 years+ - NCT06806267Recruiting
VR therapy with brain stimulation for PTSD in Ukrainians
This study tests if combining virtual reality therapy with a gentle brain stimulation technique (tDCS) can help treat PTSD symptoms in Ukrainian veterans and civilians. It may offer a new way to process traumatic memories.
BerlinAges 18–75 - NCT06733376Recruiting
PTSD treatment options study
This study tests different types of talk therapy for PTSD, like CPT, PE, and STAIR. It aims to find which treatment works best for people with PTSD.
Chicago, IllinoisAges 18 years+ - NCT06719167Enrolling by invitation
Trauma treatment for adults with childhood trauma
This study tests a treatment called TIST for adults who have complex trauma symptoms from childhood. It aims to help people who haven't gotten enough relief from other therapy.
Vikersund, BuskerudAges 18 years+ - NCT06723834Enrolling by invitation
Service Dogs and PTSD Therapy for Military Members
This study tests if pairing a psychiatric service dog with a type of talk therapy helps military-connected people with PTSD. It’s for those who have been approved to get a service dog and are not already in the same therapy.
Tucson, ArizonaAges 18 years+ - NCT06679062RecruitingPhase 2
Suvorexant for alcohol use disorder and PTSD
This study tests whether the sleep medication suvorexant can help people with both alcohol use disorder and PTSD. If you're struggling with drinking, PTSD symptoms, and poor sleep, this trial may offer a new treatment option.
Los Angeles, CaliforniaAges 21–65 - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT06629064Recruiting
Memory training for PTSD symptoms
This study tests a computer-based memory training program for people with PTSD. It aims to see if this training can help reduce PTSD symptoms by improving how your brain processes memories. The study involves 8 remote sessions over 4 weeks and two MRI scans to look at brain changes.
San Diego, CaliforniaAges 18–65 - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT06570213RecruitingEarly Phase 1
Neck injection plus talk therapy for PTSD
This study tests whether a combination of a neck injection (stellate ganglion block) and a talk therapy called Cognitive Processing Therapy helps treat PTSD better than either alone. Participants will get two injections two weeks apart, plus a week of daily therapy sessions.
Chicago, IllinoisAges 18 years+ - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06464952Recruiting
Prebiotics for PTSD and cirrhosis
This trial tests if a prebiotic supplement can improve gut health and PTSD symptoms in people with cirrhosis and PTSD. It aims to see if changing the gut microbiome can help both conditions.
Richmond, VirginiaAges 18 years+ - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT06419959Recruiting
NightWare app for veterans with PTSD and sleep problems
This study tests a smartwatch app called NightWare that may reduce nightmares and improve sleep in veterans with PTSD. It could also help heart health by improving sleep quality.
Aurora, ColoradoAges 22–88 - NCT06285708Recruiting
Making PTSD therapy safer for people with suicidal thoughts
This study tests whether a type of therapy called Prolonged Exposure can be more effective and safe for people who have both PTSD and suicidal thoughts. The goal is to help reduce trauma symptoms while addressing suicide risk.
Columbus, OhioAges 18 years+ - NCT06266364Recruiting
Vagus nerve stimulation for treatment-resistant PTSD
This study tests if stimulating the vagus nerve with an implanted device can help adults with chronic PTSD who haven't gotten better with standard treatments. You would have the device implanted and then follow the study plan for several months.
Austin, TexasAges 22–79 - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT06047691Recruiting
Couples therapy for veterans with PTSD
This study compares two types of couples counseling for military couples where one partner has PTSD. It aims to see if intensive couples therapy improves relationships and PTSD symptoms better than a relationship education program.
San Antonio, TexasAges 18 years+ - NCT05974631Recruiting
Treatments for suicidal Veterans with PTSD
This study tests two types of therapy to help Veterans with PTSD who are struggling with suicidal thoughts and self-harm. It compares a treatment called DBT (Dialectical Behavior Therapy, which helps with emotions) with another called PE (Prolonged Exposure, which helps with trauma).
Minneapolis, MinnesotaAges 18 years+ - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 296 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.