Clinical trials
Posttraumatic Stress Disorder clinical trials
Below are recruiting posttraumatic stress disorder clinical trials, each written for real people, not researchers. We’re tracking 108 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06363968Recruiting
Eye tests to predict PTSD treatment response in veterans
This study looks at whether certain eye tests can help predict how well PTSD treatments work. It's for veterans with PTSD who are not taking certain medications and have no serious eye or health conditions.
Seattle, WashingtonAges 21–75 - NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT07771530RecruitingPhase 2
Medication or dog therapy for PTSD symptoms
This study tests whether a combination of two medications (reboxetine and Ritalin) is more effective than dog-assisted therapy for reducing PTSD symptoms. Participation involves either taking the medications or attending dog therapy sessions.
HaifaAges 18–70 - NCT07630428Enrolling by invitation
Support programs after sexual assault medical exam
This study tests two support programs—STAR and TextSTAR—designed to help people after a sexual assault medical exam. The goal is to see which approach better supports your recovery and connects you with resources.
Louisville, KentuckyAges 18 years+ - NCT07565311Recruiting
Intensive Two-Week Outpatient Treatment for PTSD
This study tests a concentrated two-week outpatient program designed to help people with post-traumatic stress disorder (PTSD) recover from trauma. The goal is to see if intensive treatment delivered over a short period can effectively reduce PTSD symptoms.
OsloAges 18–65 - NCT07317206RecruitingPhase 2
Ayahuasca vs Esketamine for PTSD
This trial tests two treatments—ayahuasca and esketamine—to see if they can help people with PTSD. It's for people who have PTSD and no other health problems.
Ribeirão Preto, São PauloAges 18–65 - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07238192Recruiting
Testing a therapy to reduce suicide risk in veterans with PTSD
This trial is testing whether a therapy called Cognitive Processing Therapy (CPT), given in an intensive format, can reduce suicide risk in veterans and active duty service members with PTSD. It aims to see if this approach is more effective than standard care at preventing suicidal thoughts and behaviors.
Fort Hood, TexasAges 18 years+ - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07220681Recruiting
Integrated Care for PTSD
This study tests whether combining different treatments can help Veterans with PTSD. It focuses on those who can receive Cognitive Processing Therapy (CPT) at a VA site.
Little Rock, ArkansasAges 18 years+ - NCT07219056Recruiting
Sound therapy for adults with trauma and addiction
This trial tests a sound-based program (Safe & Sound Protocol) to help adults with both trauma and substance use disorder in residential treatment. It aims to see if this gentle listening therapy can calm the nervous system and support recovery.
Wernersville, PennsylvaniaAges 18–75 - NCT06193161Recruiting
Prolonged Exposure Therapy for PTSD in Immigrants
This trial tests prolonged exposure therapy for immigrants in Sweden who have PTSD. You will receive this online therapy to see if it helps reduce trauma symptoms.
SolnaAges 18 years+ - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07055633Recruiting
Improving cognitive rehab for veterans with concussion and PTSD
This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.
San Diego, CaliforniaAges 18 years+ - NCT07009158RecruitingPhase 1/Phase 2
Ketamine plus therapy for pain and PTSD
This trial tests if ketamine combined with talk therapy helps people with both chronic pain and PTSD. Participants receive ketamine through an IV in group therapy sessions over several weeks, with the goal of reducing pain and PTSD symptoms.
Kingston, OntarioAges 18–64 - NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT06820138RecruitingPhase 2
Focused ultrasound treatment for PTSD in veterans
This study tests a non-invasive treatment called focused ultrasound for veterans with PTSD. Focused ultrasound uses sound waves to target specific brain areas without surgery. It aims to reduce PTSD symptoms like distress and anxiety.
Providence, Rhode IslandAges 22–70 - NCT06788678Recruiting
Web-based moral elevation for veterans with PTSD
This trial tests a website designed to help veterans with PTSD feel inspired by stories of others' good deeds, which may reduce PTSD symptoms. You would complete sessions online and answer questions about your experiences.
Temple, TexasAges 18 years+ - NCT05837845RecruitingPhase 2
MDMA plus therapy versus therapy alone for severe PTSD
This Phase 2 study compares MDMA-assisted Cognitive Processing Therapy (a structured talk-therapy) to Cognitive Processing Therapy alone for Veterans with severe PTSD. It aims to see whether adding MDMA helps reduce PTSD symptoms and improve recovery.
Palo Alto, CaliforniaAges 18 years+ - NCT06630884RecruitingPhase 1
Immune response to trauma and fear
This study looks at how the body's immune and stress systems work together in people who have experienced trauma, by giving a harmless vaccine to temporarily boost inflammation. It may help explain why some people develop PTSD and others don't, which could lead to better treatments.
San Francisco, CaliforniaAges 18–65 - NCT06573970RecruitingPhase 4
Atomoxetine for PTSD and executive function in veterans
This trial tests if the medication atomoxetine can improve thinking and memory in veterans with PTSD and attention difficulties. It may help those who have not responded fully to other treatments.
Charleston, South CarolinaAges 18–75 - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15
Hear when a new Posttraumatic Stress Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for posttraumatic stress disorder?
- Yes. Clin2 currently lists 108 recruiting posttraumatic stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.