Clinical trials
Posttraumatic Stress Disorder clinical trials
Below are recruiting posttraumatic stress disorder clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06219408Recruiting
Stepped care for chronic pain and PTSD
This study tests a stepped-care program that combines complementary health approaches for people who have both chronic pain and PTSD. It aims to help patients manage both conditions together using treatments like acupuncture, massage, or mind-body therapy.
Seattle, WashingtonAges 18 years+ - NCT06234969Recruiting
Brain stimulation for PTSD: a learning study
This study tests whether a non-invasive brain stimulation technique called cTBS can help people with PTSD learn to overcome fear. You will have brain scans and receive stimulation to see if it improves how your brain processes fear-related memories.
Philadelphia, PennsylvaniaAges 18–60 - NCT06348472Recruiting
Biomarkers and PTSD psychotherapy response
This study is looking at whether certain biomarkers in your blood (related to inflammation and the oxytocin system) can predict how well you respond to trauma-focused psychotherapy. It may help find better ways to personalize PTSD treatment.
Hod HaSharonAges 18–80 - NCT06363968Recruiting
Eye tests to predict PTSD treatment response in veterans
This study looks at whether certain eye tests can help predict how well PTSD treatments work. It's for veterans with PTSD who are not taking certain medications and have no serious eye or health conditions.
Seattle, WashingtonAges 21–75 - NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06429293Recruiting
Talk therapy for PTSD and heart health
This study tests whether cognitive behavioral therapy (a type of talk therapy) can improve heart health in people with PTSD. If you have PTSD and are at risk for or have heart disease, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06535516Recruiting
Supporting youth and families after tough experiences
This study tests a program to help youth ages 10-15 who have faced child maltreatment, like abuse or neglect. It aims to build resilience in both the youth and their family.
Rochester, New YorkAges 10–15 - NCT06630884RecruitingPhase 1
Immune response to stress after trauma
This study looks at how the immune system responds to a mild stress (a typhoid vaccine) in people who have been through trauma but do not have PTSD. It may help understand why some people are more susceptible to inflammation after trauma.
San Francisco, CaliforniaAges 18–60 - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT06573970RecruitingPhase 4
Atomoxetine for PTSD and executive function in veterans
This trial tests if the medication atomoxetine can improve thinking and memory in veterans with PTSD and attention difficulties. It may help those who have not responded fully to other treatments.
Charleston, South CarolinaAges 18–75 - NCT07055633Recruiting
Improving cognitive rehab for veterans with concussion and PTSD
This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.
San Diego, CaliforniaAges 18 years+ - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07176273Recruiting
Personalized PTSD Treatment for Veterans
This trial helps veterans with PTSD choose between two proven talk therapies—Prolonged Exposure (PE) or Cognitive Processing Therapy (CPT)—and uses a smartphone app to support their treatment. The goal is to see which approach works best for each person.
Augusta, GeorgiaAges 18 years+ - NCT07220681Recruiting
Integrated Care for PTSD
This study tests whether combining different treatments can help Veterans with PTSD. It focuses on those who can receive Cognitive Processing Therapy (CPT) at a VA site.
Little Rock, ArkansasAges 18 years+ - NCT07238192Recruiting
Testing a therapy to reduce suicide risk in veterans with PTSD
This trial is testing whether a therapy called Cognitive Processing Therapy (CPT), given in an intensive format, can reduce suicide risk in veterans and active duty service members with PTSD. It aims to see if this approach is more effective than standard care at preventing suicidal thoughts and behaviors.
Fort Hood, TexasAges 18 years+ - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT07317206RecruitingPhase 2
Ayahuasca vs Esketamine for PTSD
This trial tests two treatments—ayahuasca and esketamine—to see if they can help people with PTSD. It's for people who have PTSD and no other health problems.
Ribeirão Preto, São PauloAges 18–65 - NCT05457985Recruiting
Adaptive app coaching for PTSD in community health clinics
This study tests a flexible (adaptive) approach using a mobile app to help improve treatment outcomes for posttraumatic stress disorder (PTSD) for people getting care at participating community health clinics. It may help you get more tailored support between visits.
Baldwin, MichiganAges 18 years+ - NCT07630428Enrolling by invitation
Support programs after sexual assault medical exam
This study tests two support programs—STAR and TextSTAR—designed to help people after a sexual assault medical exam. The goal is to see which approach better supports your recovery and connects you with resources.
Louisville, KentuckyAges 18 years+ - NCT07565311Recruiting
Intensive Two-Week Outpatient Treatment for PTSD
This study tests a concentrated two-week outpatient program designed to help people with post-traumatic stress disorder (PTSD) recover from trauma. The goal is to see if intensive treatment delivered over a short period can effectively reduce PTSD symptoms.
OsloAges 18–65 - NCT06954025Enrolling by invitationPhase 2
MDMA therapy for PTSD inpatients
This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.
OegstgeestAges 18 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT06826937Recruiting
Short-term recall therapy for severe PTSD
This study tests a new therapy that uses short-term recall and reprocessing to help people with severe PTSD. It may help you if you have strong PTSD symptoms and are not currently in crisis or have certain other mental health conditions.
BeershebaAges 18–70
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Common questions
- Are there clinical trials for posttraumatic stress disorder?
- Yes. Clin2 currently lists 110 recruiting posttraumatic stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.