Clinical trials
PPA clinical trials
Below are recruiting ppa clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06739967Recruiting
Speech Therapy for Italian Speakers with PPA
This study tests speech and language therapy for people with primary progressive aphasia (PPA). It aims to see if targeted exercises can help maintain or improve communication skills.
BariAges 40–85 - NCT07158216Recruiting
Long-term effects of brain stimulation in primary progressive aphasia
This study tests whether brain stimulation can help people with primary progressive aphasia (a type of dementia that mainly affects language) maintain or improve their communication skills over time. It looks at two types of stimulation: transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).
MadridAges 18 years+ - NCT07260253Recruiting
Remote brain stimulation for language in primary progressive aphasia
This study tests if a non-invasive brain stimulation technique called tDCS, done at home with remote supervision, can help improve language skills in people with the logopenic variant of primary progressive aphasia (PPA).
San Francisco, CaliforniaAges 40 years+ - NCT03887481Recruiting
Brain stimulation study for a language-loss dementia subtype
This trial tests whether a painless form of brain stimulation can improve language and thinking skills in people with the logopenic variant of primary progressive aphasia (a dementia that affects language). You may receive brain stimulation along with repeated clinic visits to track changes over time.
Baltimore, MarylandAges 50–80 - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06613204Recruiting
Support program for family caregivers of FTD patients
This study tests a behavior change program for family members caring for someone with frontotemporal degeneration (FTD). It aims to help caregivers manage upsetting behaviors and reduce stress.
Portland, OregonAges 18–100 - NCT06863571RecruitingPhase 3
Early medication combo to reduce swelling after stroke
This trial tests a combination of medicines given early after a large ischemic stroke to reduce brain swelling. It may help people who have had a stroke in the middle cerebral artery within the last 3 days and have a large area of brain damage.
Hangzhou, ZhejiangAges 18 years+ - NCT07219680Recruiting
Communication quality of life in primary progressive aphasia
This trial tests a therapy to improve communication for people with primary progressive aphasia (PPA), a condition that slowly affects language. You and a care partner will attend video sessions to work on communication goals together.
Austin, TexasAges 40 years+ - NCT07316413Recruiting
Repetitive TMS for frontotemporal degeneration
This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can help people with frontotemporal lobar degeneration. It is a non-invasive brain stimulation technique that may improve symptoms.
Brescia, ItalyAges 18 years+ - NCT01818661RecruitingPhase 4
Imaging study for progressive apraxia of speech
This trial uses repeated brain scans to study how progressive apraxia of speech changes over time. It may help doctors better understand the condition and improve future tracking and care.
Rochester, MinnesotaAges 18 years+ - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT06921265Enrolling by invitation
Magnetic brain stimulation for language in primary progressive aphasia
This study tests whether targeted magnetic stimulation to the brain can help improve language and speech in people with primary progressive aphasia. It compares the effects of real stimulation versus a placebo to see if it is a safe and useful treatment.
Milan, MilanoAges 40–85 - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+
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Common questions
- Are there clinical trials for ppa?
- Yes. Clin2 currently lists 13 recruiting ppa studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ppa trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ppa trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.