Clinical trials
Prediabetic State clinical trials
Below are recruiting prediabetic state clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06897982Recruiting
Nutrition program for prediabetes at health center
This study tests a nutrition program for people with prediabetes at a health center. It aims to see if the program is practical and can help prevent type 2 diabetes.
Los Angeles, CaliforniaAges 18–99 - NCT07713030Recruiting
Exercise types for prediabetes: high-intensity vs. steady
This study compares two exercise programs (short bursts of intense activity vs. longer, steady exercise) to see which works better for people with prediabetes. It may help you prevent or manage diabetes through a structured fitness routine.
Lahore, Punjab ProvinceAges 35–54 - NCT05340868Recruiting
Study body response to oral semaglutide in overweight adults
This study looks at how genetics may affect your body’s early response to oral semaglutide, a weight-related diabetes medicine. You may be considered if you are overweight (or overweight with prediabetes) and can safely take part in the research.
Bialystok, Podlaskie VoivodeshipAges 18–65 - NCT06750783RecruitingPhase 4
Xuezhikang vs Atorvastatin for high cholesterol and prediabetes
This trial compares two treatments (Xuezhikang, a red yeast rice supplement, and Atorvastatin, a common statin) to see which works better for lowering cholesterol in people with prediabetes. It may help you understand if a natural option is as effective as a standard medication.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05351476Recruiting
Exercise program for metabolism in postmenopausal women
This trial studies whether a structured exercise program can improve how your body uses fat. It is designed for postmenopausal women with higher weight and prediabetes who are not currently exercising much.
Tallahassee, FloridaAges 50–75 - NCT06723886Recruiting
Can olive pomace oil help control blood sugar?
This study tests whether olive pomace oil, a type of olive oil, can lower blood sugar in people with prediabetes or diabetes. It may be an option if you have high blood sugar and are not taking other medications or supplements.
Madrid, MadridAges 20–70 - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT05123963Recruiting
Timed lifestyle plan to improve blood sugar in prediabetes
This trial tests whether matching daily lifestyle habits to a 24-hour body rhythm can improve blood sugar levels in people with prediabetes. You may be asked to follow a detailed schedule and avoid certain medicines for a short time before study visits.
Sherbrooke, QuebecAges 45–75 - NCT05835037RecruitingPhase 4
Zinc supplement study for prediabetes blood sugar control
This study tests whether taking zinc can improve how your body controls blood sugar in people with prediabetes. It may help slow the progression toward type 2 diabetes, but you would need to meet specific health and medication criteria.
Lancaster, PennsylvaniaAges 18–80 - NCT06067139Recruiting
Sleep therapy to lower diabetes risk in prediabetes
This study tests if a sleep-focused therapy (cognitive behavioral therapy for insomnia, or CBT-I) can lower diabetes risk in people with prediabetes and insomnia. Participants will receive online therapy sessions and wear a monitor to track blood sugar and sleep.
Portland, OregonAges 22–79 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06426277Recruiting
Brazilian diabetes prevention program
This study tests a program that helps people with prediabetes make healthy lifestyle changes to prevent type 2 diabetes. You would get support through your own device at home, with no need for in-person visits.
Goiânia, GoiásAges 18 years+ - NCT06481020Recruiting
Plant sterols for heart health in overweight adults
This study tests whether plant sterols (natural compounds found in plants) can help improve cholesterol and other heart health markers. If you are overweight and have high LDL cholesterol, you may be able to join this study to see if adding plant sterols to your diet helps.
ValenciaAges 18–80 - NCT06580964Recruiting
Heat and exercise therapy for aging adults with prediabetes
This study tests whether combining exercise with heat therapy can help older adults with prediabetes improve their health. It may offer a new way to manage blood sugar without medication.
Lubbock, TexasAges 50 years+ - NCT06690788Recruiting
Couples program to prevent type 2 diabetes (PreventT2 Together)
This research study looks at whether a lifestyle program designed for couples can help prevent type 2 diabetes. Both partners take part together, and the program is based on the National Diabetes Prevention Program.
Salt Lake City, UtahAges 18 years+ - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT07605169Recruiting
Long-Term Health Effects of Lifestyle Changes
This study follows people who already completed a lifestyle intervention program to see how diet and exercise changes affect their health and well-being over time. Researchers want to understand if these changes have lasting benefits.
Gothenburg, Västra Götaland CountyAges 45–65 - NCT07140848Recruiting
CGM-enhanced program to prevent type 2 diabetes in prediabetes
This trial tests whether adding continuous glucose monitors (CGMs) to a proven lifestyle program helps adults with prediabetes prevent type 2 diabetes. You'll attend coaching sessions and wear a small sensor to track your blood sugar.
Buffalo, New YorkAges 18 years+ - NCT07235358Recruiting
Pecan snacking for prediabetes health study
This study tests if eating pecans daily as a snack can improve heart health and blood sugar control in people with prediabetes. You would replace typical sugary or fatty snacks with pecans for several weeks, and researchers will track changes in your cholesterol and blood sugar.
University Park, PennsylvaniaAges 25–65 - NCT06963736Recruiting
Reducing health risks from too much evening screen time
This study tests simple strategies to help people who spend a lot of time on screens at night and eat after 8pm. It aims to reduce health risks like high blood pressure, belly fat, and blood sugar issues.
Tempe, ArizonaAges 26 years+ - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59
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Prediabetic State trials by city
Studies with a site in or near these metro areas.
Prediabetic State trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for prediabetic state?
- Yes. Clin2 currently lists 26 recruiting prediabetic state studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prediabetic state trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prediabetic state trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.