Metformin for prediabetes to reduce heart and blood-vessel events
Treatments studied
Part of Brain & nervous system, Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have prediabetes (higher-than-normal blood sugar, but not diabetes).
- You have known atherosclerotic cardiovascular disease (heart, brain/carotid, or leg artery problems).
- Your kidney function is good enough (eGFR at least 45).
- You can sign consent and agree to follow the study procedures.
- You have not taken metformin (or other diabetes medicines) in the last 12 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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