Clinical trials
Primary Care clinical trials
Below are recruiting primary care clinical trials, each written for real people, not researchers. We’re tracking 287 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06676384RecruitingPhase 4
Testing additional drugs for IgA nephropathy in South Asian patients
This trial is testing if adding another approved drug to standard treatment can slow kidney function decline in people with IgA nephropathy. It aims to find better options for South Asian adults with this condition.
Nadiād, GujaratAges 18–65 - NCT07045623Recruiting
Better care and education for high cholesterol
This study compares two ways of managing high cholesterol: a more intensive program with extra support versus the usual care and education. It's for people with high blood pressure or diabetes who are already part of a community health program.
Gyeonggi-do, Suwon-siAges 30–80 - NCT06650878Recruiting
Desarda vs Lichtenstein hernia repair comparison
This trial compares two surgical techniques for repairing a first-time inguinal hernia (a bulge in the groin). Both methods aim to fix the hernia with a mesh, but the Desarda technique uses a piece of your own abdominal muscle, while the Lichtenstein technique uses a synthetic mesh. The study will see which approach leads to fewer complications and better recovery.
Sant Pere de Ribes, BarcelonaAges 18 years+ - NCT05940623Recruiting
Home eye pressure monitoring for glaucoma
This study tests whether measuring your eye pressure at home with a special device can help control glaucoma and slow its progression. It may offer a more convenient way to track your condition between doctor visits.
Wong Chuk HangAges 18 years+ - NCT07869069Recruiting
Mobile heart health visits for remote communities
This study brings heart health checkups to Indigenous and remote communities using a mobile health unit. It aims to improve heart disease prevention and make healthcare more accessible.
Québec, QuebecAges 35–65 - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+ - NCT06690528RecruitingPhase 2
Surgery vs. palliative care for pancreatic cancer with limited liver spread
This trial compares surgery to remove the primary tumor and up to 3 liver spots against standard palliative care for people with pancreatic cancer that has spread only to the liver (up to 3 spots). It is for those whose cancer has not grown after initial chemotherapy and who are healthy enough for surgery.
Padova, ItalyAges 18–75 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT07019623Recruiting
U-CaVIT device vs standard care for preventing heavy bleeding after c-section
This study tests a new device called U-CaVIT to prevent heavy bleeding after a planned cesarean delivery in women at high risk. It compares the U-CaVIT device to standard care to see which works better.
ZurichAges 18 years+ - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT07135882RecruitingPhase 3
Radiotherapy for lung cancer that has spread
This trial tests whether giving radiotherapy to the main lung tumor, along with the usual medicines (like chemotherapy or immunotherapy), can help people with stage IV lung cancer. The goal is to see if adding this treatment helps control the cancer and improves how long patients live.
Gold Coast, QueenslandAges 18 years+ - NCT06824467RecruitingPhase 3
Maintenance Therapy Study for Recurrent Ovarian Cancer
This study tests a new maintenance treatment (sacituzumab tirumotecan) versus standard care for people with ovarian cancer that has come back after responding to platinum-based chemotherapy. The goal is to see if it can keep the cancer from growing longer and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT04988009Recruiting
Telemedicine care experience survey for brain tumor patients
This trial asks brain tumor patients and caregivers to share what they think about the quality of care they receive through telemedicine. Your feedback may help improve how neuro-oncology visits are done by video in the future.
Houston, TexasAges 18 years+ - NCT03691480Recruiting
Treating a collapsed lung at home: valve pigtail vs air removal
This study compares two ways to treat a first-time, spontaneous collapsed lung (pneumothorax): a small tube with a one-way valve versus removing air with a needle. It aims to see which approach works better and is easier to manage for people treated as outpatients.
LorientAges 18–50 - NCT07512921Recruiting
Gene Expression Study for HPV-Negative Head and Neck Cancer
This study compares gene patterns in tumor tissue and blood samples from patients with HPV-negative head and neck cancer. Understanding these patterns may help doctors better understand the disease and develop better treatments.
MilanAges 18 years+ - NCT06855706Recruiting
Personalized physical activity program for ovarian and endometrial cancers
This study tests whether a personalized, automated physical activity program (using a Fitbit and continuous glucose monitor) can improve immune function and health outcomes in people with advanced ovarian, primary peritoneal, fallopian tube, or newly diagnosed endometrial cancer. You'll wear an activity tracker, answer questionnaires, and provide blood and stool samples at Roswell Park.
Buffalo, New YorkAges 18 years+ - NCT07480954RecruitingPhase 1/Phase 2
CAR-NK cell therapy for recurrent ovarian cancer
This trial tests a new type of immune cell therapy (CAR-NK cells) that targets two proteins often found on ovarian cancer cells. It is for people whose cancer has come back after at least two prior treatments.
Shenzhen, GuangdongAges 18–75 - NCT07536802RecruitingPhase 4
Adenosine Safety and Benefit in Emergency Heart Attack Treatment
This study tests whether giving a medication called adenosine before emergency heart catheterization (a tube procedure to open blocked arteries) helps patients having a heart attack. Adenosine may protect heart tissue and improve outcomes.
Karachi, SindhAges 18–80 - NCT07230743Recruiting
Using an interactive projector to reduce anxiety in children during anesthesia
This trial tests whether an interactive projector can help distract children aged 2 to 6 while they are going under anesthesia for surgery, with the goal of lowering their anxiety. It compares the projector to standard care to see if it makes the experience less stressful for the child and family.
Vitacura, Santiago MetropolitanAges 2–6 - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT05429970Recruiting
Reducing stress before ovarian cancer surgery with two medicines
This study tests whether giving two commonly used medicines before surgery—one that can lower stress on the body (a beta-blocker) and one that reduces inflammation (a COX-2 inhibitor)—can improve outcomes compared with standard care. It’s for people with advanced ovarian, fallopian tube, or primary peritoneal cancer who are having open surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT06589804RecruitingPhase 3
Testing cetuximab plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding cetuximab to the standard drug pembrolizumab works better for head and neck cancer that has spread or come back after treatment. It is for people whose cancer did not respond to platinum chemotherapy and whose tumors have a certain immune marker (PD-L1).
Little Rock, ArkansasAges 18 years+
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Common questions
- Are there clinical trials for primary care?
- Yes. Clin2 currently lists 287 recruiting primary care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.