Clinical trials
Primary Care clinical trials
Below are recruiting primary care clinical trials, each written for real people, not researchers. We’re tracking 287 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05681767Recruiting
Lifestyle coaching to support depression care in primary clinics
This trial studies whether motivational, multi-part lifestyle coaching can help adults with depression when they start treatment through a regular primary care clinic. If you’re eligible, the program may add supportive skills to help improve mood alongside usual care.
KuopioAges 18 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT05904353Recruiting
Care coordination program after hip fracture and osteoporosis
This trial aims to improve how primary care and hospital care work together to treat osteoporosis after a hip fracture. It may help by making follow-up treatment plans and communication clearer after your hip injury.
Lørenskog, AkershusAges 75 years+ - NCT07625176Enrolling by invitation
App-guided decisions for lung lining disease
This trial tests whether a decision-support app helps doctors better manage conditions affecting the pleura (the lining around your lungs)—like collapsed lung, fluid buildup, or infection. You'd be randomly assigned to use the app approach or standard care, and the study tracks how well each works.
AalborgAges 18 years+ - NCT07325994Recruiting
Pain control during hysteroscopy for women with infertility
This trial tests if using calming words (verbal analgesia) during a hysteroscopy can reduce pain compared to standard care. It is for women with primary infertility who need this procedure to check the uterus.
GizaAges 18–40 - NCT07224594Enrolling by invitation
Comparing palliative care models for seriously ill patients
This trial compares two ways of providing palliative care to hospitalized patients who are likely to pass away within the next year. It aims to see which approach better meets patients' needs and improves their quality of life.
Pasadena, CaliforniaAges 18 years+ - NCT07761364Recruiting
Contact with family in the intensive care unit
This study looks at how a visit from your main family caregiver affects your body while you are in the intensive care unit (ICU). It aims to see if having that personal contact can help you feel better and recover.
Mexico City, Mexico CityAges 18–59 - NCT06943053Recruiting
Waterproof bandage study for knee replacement recovery
This study compares two types of waterproof bandages used after total knee replacement surgery to see which one works better at keeping the wound dry and clean.
Pathum Thani, Khlong luangAges 55 years+ - NCT06613204Recruiting
Support program for family caregivers of FTD patients
This study tests a behavior change program for family members caring for someone with frontotemporal degeneration (FTD). It aims to help caregivers manage upsetting behaviors and reduce stress.
Portland, OregonAges 18–100 - NCT07350850RecruitingPhase 2
Methotrexate plus immunotherapy combo for untreated PCNSL
This trial tests a new combination of drugs (methotrexate, rituximab, sintilimab, and pirtobrutinib) against standard therapy for people with newly diagnosed primary central nervous system lymphoma (PCNSL) that has not been treated before. It aims to see if the combo works better and has manageable side effects.
Xiamen, FujianAges 18 years+ - NCT06962800RecruitingPhase 3
Study of felzartamab for adults with primary membranous nephropathy
This study tests whether felzartamab, given as an infusion, can help treat primary membranous nephropathy (a kidney disease causing protein in the urine and swelling). It may reduce protein loss and improve kidney function compared to standard care alone.
Huntsville, AlabamaAges 18–80 - NCT06310148Recruiting
Preventing chronic disease in Hong Kong adults aged 45+
This study looks at a new program in Hong Kong that helps people without diabetes or hypertension learn how to prevent or manage chronic diseases. One group gets extra support through a local health centre, and the other group follows usual care.
Hong KongAges 45 years+ - NCT06990659Recruiting
Outpatient vs. Inpatient Liver Cancer Treatment Study
This study compares having your liver cancer treatment (TACE or TARE) as an outpatient versus staying in the hospital overnight. It's for people with primary liver cancer whose liver and kidney function are good enough and who can safely go home the same day with support.
AmiensAges 18 years+ - NCT04834544RecruitingPhase 2
Maintenance vaccine treatment after first chemotherapy for ovarian cancer
This Phase 2 trial studies a maintenance vaccine (DCVAC/OvCa) given after standard first-line chemotherapy and surgery for certain advanced ovarian cancers. It aims to help keep the cancer from coming back for longer by boosting the body’s anti-cancer response.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT07161245Recruiting
Fatigue relief study for primary biliary cholangitis
This trial tests a program of exercise, nutrition, and education to help reduce fatigue in people with primary biliary cholangitis. It aims to see if this program can improve energy and quality of life.
Barcelona, BarcelonaAges 18–80 - NCT07496996Recruiting
Support program for disability transitional care stays
This study looks at whether a special support program can help prevent problems and improve the experience of people with disabilities during a 4-week stay in a transitional care unit. The study also includes family or friend caregivers to see how the program works for them as well.
RennesAges 18 years+ - NCT05574673Recruiting
Study of DNA repair traits in ovarian cancer patients
This study looks at certain “DNA repair traits” (called homologous recombination phenotype) in people with epithelial ovarian cancer. Results may help researchers better understand who responds to platinum chemotherapy, which is commonly used for this cancer.
København Ø, Region SjællandAges 18–100 - NCT07230886Recruiting
Reducing transplant complications with enhanced preservation
This trial tests a new way to preserve donated lungs before transplant to lower the risk of complications. It may help primary graft dysfunction, a serious lung problem after surgery.
Toronto, OntarioAges 17 years+ - NCT06249958Recruiting
Personalized rehabilitation after hip or knee replacement
This study looks at how personalized rehabilitation after hip or knee replacement surgery can improve your quality of life. It is for people who had their surgery at IRCCS Galeazzi Orthopedic Institute in 2019.
Milan, ItaliaAges 18 years+ - NCT07262840Recruiting
Health behavior change for people at high risk for colorectal cancer
This trial tests a program to help people at high risk for colorectal cancer change their health behaviors to lower their risk. It might help you if you are worried about your risk and want to make positive changes.
Shenyang, LiaoningAges 1.5 years–6.7 years - NCT05934084Recruiting
Lifestyle plan for heart and health after lymphoma remission
This trial tests a structured lifestyle and survivorship care plan for people who finished treatment for certain lymphoma types and are now in long-term remission. The goal is to support long-term health (including heart-related monitoring) and reduce future risks.
Ancona, AnconaAges 18–50 - NCT07147647Recruiting
Laser treatment for lowering eye pressure in Black patients with glaucoma
This trial tests a laser procedure called DSLT to reduce eye pressure in Black patients with mild to moderate open-angle glaucoma. It aims to see if this treatment works well as a first step before using eye drops.
Elkridge, MarylandAges 18 years+ - NCT07843277Recruiting
Improving sepsis care in Indonesian emergency rooms
This study tests whether a special medical chart helps doctors spot sepsis earlier and reduce deaths in Indonesian hospitals. If you or your loved one are diagnosed with sepsis in the emergency department, this could improve care and outcomes.
Jakarta Pusat, DKI JakartaAges 18 years+
Hear when a new Primary Care trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for primary care?
- Yes. Clin2 currently lists 287 recruiting primary care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.