Clinical trials
Primary Graft Dysfunction clinical trials
Below are recruiting primary graft dysfunction clinical trials, each written for real people, not researchers. We’re tracking 8 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05950724Enrolling by invitationEarly Phase 1
TNF blocker to protect lungs after transplant
This early-stage trial tests whether blocking a specific inflammation signal (TNF-alpha) can help prevent or improve kidney problems and early graft (new lung) dysfunction after a lung transplant at Northwestern. You might be eligible if you’re scheduled for that transplant and are willing to go through study consent and follow-up.
Chicago, IllinoisAges 18 years+ - NCT00552357Recruiting
Finding risk factors for poor lung transplant function
This study looks at what increases the chance of developing a serious complication called “primary graft dysfunction” shortly after a lung (or heart-lung) transplant. The results may help doctors better predict risk and improve care after transplant.
Philadelphia, PennsylvaniaAges 13–68 - NCT07230886Recruiting
Reducing transplant complications with enhanced preservation
This trial tests a new way to preserve donated lungs before transplant to lower the risk of complications. It may help primary graft dysfunction, a serious lung problem after surgery.
Toronto, OntarioAges 17 years+ - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT05375149Recruiting
Breath particle study after lung transplant
This study looks at tiny particles in exhaled breath after a lung transplant. It may help researchers understand how the lungs are doing after transplant by using breath samples.
Lund, Skåne CountyAges 16–75 - NCT03541889RecruitingPhase 1
Tracking blood stem cell transplant success with special imaging
This study uses a safe PET scan–type imaging test to look for signs that a stem cell transplant has “taken” (engrafted). It may help doctors understand why some transplants fail and how to improve chances of success.
Atlanta, GeorgiaAges 4–80 - NCT05562869RecruitingPhase 3
Belatacept instead of tacrolimus for early kidney graft problems
This trial looks at replacing standard anti-rejection medicines (tacrolimus, a type of CNI, plus mycophenolate and possibly prednisone) with belatacept in adults who have early kidney graft dysfunction 3–12 months after a kidney transplant. It aims to see if belatacept can control rejection and protect kidney function in the right patients.
Nantes, Loire AtlantiqueAges 18–99 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+
Hear when a new Primary Graft Dysfunction trial opens
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Common questions
- Are there clinical trials for primary graft dysfunction?
- Yes. Clin2 currently lists 8 recruiting primary graft dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary graft dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary graft dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.