Clinical trials
Primary Peritoneal Cancer clinical trials
Below are recruiting primary peritoneal cancer clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04595929Recruiting
Tested aerosol chemotherapy inside the abdomen for stomach cancer
This trial looks at a way to give chemotherapy into the abdomen (through a small tube during laparoscopy) for certain stomach cancers. It aims to see whether this approach improves cancer control and surgical outcomes for people whose tumors can potentially be removed.
Saint PetersburgAges 18–65 - NCT04469764RecruitingPhase 2
Abemaciclib for certain recurrent ovarian or endometrial cancers
This Phase 2 study tests abemaciclib, a targeted pill treatment, for recurrent ovarian or endometrial cancer that shows specific tumor genetic patterns. It may help slow or control cancer growth in people whose tumor matches the required test results.
Los Angeles, CaliforniaAges Any age - NCT07291180Recruiting
Personalized heated chemo for advanced appendix or colon cancer
This study tests a personalized way to deliver heated chemotherapy directly into the belly during surgery for advanced appendix or colorectal cancer that has spread to the lining of the abdomen. The goal is to see if tailoring the chemo drugs to your tumor can improve outcomes.
New Haven, ConnecticutAges 18–81 - NCT07004647Recruiting
MT027 cell injection for advanced peritoneal tumors
This trial tests an experimental cell therapy, MT027, for people with advanced peritoneal tumors that have stopped responding to standard treatments. The goal is to see if MT027 can shrink tumors when injected directly into the abdomen.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06730347RecruitingPhase 2
Study of lorigerlimab for advanced ovarian and other cancers
This trial tests a new drug, lorigerlimab, for people with certain types of ovarian cancer or related cancers that have come back or not responded to treatment. The goal is to see if the drug can help shrink tumors or slow the disease.
Los Angeles, CaliforniaAges 18 years+ - NCT07738172RecruitingPhase 3
Osimertinib with or without lung tumor surgery for EGFR-mutated non-small cell lung cancer
This study tests whether adding surgery to remove the main lung tumor improves outcomes for people with stage 4 lung cancer that has a specific EGFR mutation and only limited spread. If you qualify, you will take the targeted drug osimertinib for 12 weeks, and if the tumor responds, you may be randomly assigned to either continue the drug alone or have the main tumor surgically removed and then continue the drug.
Taipei, Taipei CityAges 18 years+ - NCT06295965Recruiting
Blood changes and cancer therapy study
This study looks at why some people develop blood disorders after cancer treatment. It monitors changes in blood cells to better predict and prevent these problems.
Seattle, WashingtonAges Any age - NCT07658196RecruitingPhase 1
TLR9 immunotherapy for stomach or appendix cancer spreading in the abdomen
This trial tests an experimental immunotherapy that targets a protein called TLR9 to help your immune system fight cancer cells that have spread into the lining of your abdomen (peritoneal carcinomatosis). It's for people with colorectal or appendix cancer that has spread this way and may also have some limited spread to the liver or lungs.
Providence, Rhode IslandAges 18 years+ - NCT06232434RecruitingPhase 2/Phase 3
New gel treatment for advanced stomach cancer that has spread
This trial tests a new gel called Prospidelong given once into the abdomen during surgery for stomach cancer that has spread to the lining of the belly. The goal is to see if it is safe and works well.
Minsk, Minsk CityAges 18–75 - NCT07285044RecruitingPhase 2
Home cancer treatment program for Florida panhandle residents
This study tests whether people with certain cancers can safely receive their regular intravenous treatments at home instead of coming to the clinic. It aims to make treatment more convenient and improve satisfaction, especially for those living in the Florida Panhandle.
Jacksonville, FloridaAges 18 years+ - NCT07277413RecruitingPhase 1
Study of IDE892 for advanced solid tumors with MTAP deletion
This study tests a new drug called IDE892, alone or in combination, for people with advanced solid tumors that have a specific genetic change (MTAP deletion). The goal is to see if the drug is safe and whether it can shrink tumors.
Goodyear, ArizonaAges 18 years+ - NCT07495124RecruitingPhase 2
IGFBP-2 vaccine to prevent ovarian cancer return
This trial tests a vaccine that targets a protein called IGFBP-2 to prevent ovarian cancer from coming back. It is for people whose CA-125 blood test shows the cancer might be returning, but who don't yet have tumors visible on scans.
Seattle, WashingtonAges 18 years+ - NCT06492070RecruitingPhase 2
Cooling therapy with or without cilostazol to prevent nerve damage from paclitaxel
This study tests whether cooling your hands and feet during chemotherapy, with or without the medicine cilostazol, can help prevent nerve damage (numbness, tingling, or pain) caused by the drug paclitaxel. It is for people with gynecologic cancers who are about to start or have just finished paclitaxel treatment.
Atlanta, GeorgiaAges 18 years+ - NCT07772869Recruiting
Uterine washing test to detect ovarian cancer risk
This study is testing a new way to find ovarian cancer early. It uses a gentle washing of the uterus (like a Pap test) to collect cells and look for signs of cancer in women who are at high risk because of a BRCA gene mutation. The goal is to see if this method can detect cancer before it spreads, which might help save more lives.
Seattle, WashingtonAges 18 years+ - NCT06912152RecruitingPhase 1
Testing MT027 for advanced belly-lining cancers
This trial tests an experimental intraperitoneal therapy (MT027) for people whose advanced solid tumors have spread to the lining of the belly (peritoneum) and haven't responded to standard treatments. It aims to see if this new approach can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18–70 - NCT05564377RecruitingPhase 2
Find targeted cancer treatments using genetic testing
This study matches people with advanced solid tumors to targeted treatment plans based on genetic testing. It also requires tumor sample testing to help doctors choose the most promising therapy for your specific tumor changes.
Birmingham, AlabamaAges Any age - NCT06378905Recruiting
Testing a new score for advanced ovarian cancer
This study is testing a new scoring system (Cukurova Score) to help doctors better understand and treat advanced ovarian, fallopian tube, or peritoneal cancer. By joining, you could help improve how we predict outcomes for people with these cancers.
AdanaAges 18–100 - NCT07139951Enrolling by invitationPhase 2
Heated Chemotherapy for Stomach Cancer at High Risk of Recurrence
This trial tests a special type of chemotherapy that is heated and delivered directly into the belly during surgery (called HIPEC). It uses two drugs, cisplatin and paclitaxel, and is for people with stomach cancer who are at high risk of the cancer returning in the lining of the belly.
Rochester, MinnesotaAges 18–80 - NCT05303714RecruitingPhase 3
PIPAC plus chemo for limited peritoneal stomach cancer
This trial tests a treatment called PIPAC (medicine delivered into the abdomen through a small scope) along with “multimodal” therapy, including chemotherapy, for stomach cancer that has spread only in the lining of the abdomen in limited amounts. It may help control the cancer and prevent progression after surgery.
VeronaAges 18–75 - NCT07489287RecruitingPhase 1
GB-5267 for platinum-resistant ovarian, peritoneal, or fallopian tube cancer
This trial tests a new cell therapy (GB-5267) for people with platinum-resistant ovarian, peritoneal, or fallopian tube cancer. It requires multiple tumor biopsies and aims to see if the treatment can help when standard chemo stops working.
Buffalo, New YorkAges 18 years+ - NCT05753306RecruitingPhase 2
Robot surgery plus heated chemo for limited spread stomach cancer
This study tests a “robot-assisted” surgery to remove stomach cancer in the belly lining (peritoneum) along with heated chemotherapy placed inside the abdomen. It’s for people whose cancer has spread only in the peritoneum, aiming to control disease when there’s a good chance of removing it all.
Rochester, MinnesotaAges 18–80 - NCT06476184RecruitingPhase 3
Adjusted chemo dosing for hard-to-treat ovarian cancer
This trial tests a different way of giving chemotherapy to people with advanced ovarian cancer that didn't respond well to initial treatment. The goal is to see if changing the dose and schedule can improve outcomes.
AngersAges 18 years+ - NCT05347524Recruiting
Blood test study to detect stomach cancer spread in the belly
This study checks whether a blood liquid biopsy test can detect when stomach cancer has spread to the lining of the abdomen (peritoneal metastasis). It compares people with confirmed belly spread to people whose belly lining tests were negative, using blood samples before/around treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–74 - NCT07757165RecruitingPhase 2
Surgery after drug treatment for advanced stomach cancer
This trial is for people with advanced stomach cancer that has shrunk after initial chemotherapy or targeted therapy. It compares whether adding surgery to continued medical treatment is better than staying on medical treatment alone, with the goal of improving outcomes.
ShanghaiAges 18–75
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Common questions
- Are there clinical trials for primary peritoneal cancer?
- Yes. Clin2 currently lists 129 recruiting primary peritoneal cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary peritoneal cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary peritoneal cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Stage IV Primary Peritoneal Cancer AJCC v8
- Stage IVA Primary Peritoneal Cancer AJCC v8
- Stage IVB Primary Peritoneal Cancer AJCC v8
- Stage III Primary Peritoneal Cancer AJCC v8
- Stage IIIC Primary Peritoneal Cancer AJCC v8
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Primary Peritoneal Carcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.