Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 224 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07765004Recruiting
Probiotic supplement for constipation relief
This study tests whether a probiotic supplement can improve constipation symptoms like infrequent bowel movements or hard stools. It might help you have more regular, softer stools.
Suzhou, JiangsuAges 18–65 - NCT06474234RecruitingPhase 2
Probiotic for Gut Health in Young Children
This study tests whether a probiotic (a 'good bacteria' supplement) can help balance the gut bacteria in young children. Your child may be able to join if they are healthy, under 7, and haven't taken probiotics or antibiotics recently.
Cheras, Kuala LumpurAges 1 month–7 years - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT06943235RecruitingPhase 2
Probiotics, radiation, chemo, and immunotherapy for limited-stage small cell lung cancer
This trial tests if adding probiotics (good bacteria) to standard chemoradiation and an immunotherapy drug (adebrelimab) can help treat limited-stage small cell lung cancer. It may improve how well the treatment works and reduce side effects.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06583720RecruitingPhase 1
Light therapy and probiotics for bad breath
This trial tests a new approach for treating bad breath (halitosis) using a special light therapy combined with probiotics (good bacteria). It aims to see if this combination works better than standard treatments.
São Paulo, São PauloAges 18–60 - NCT05467150Recruiting
Probiotic supplement in pregnant people with gestational diabetes
This trial studies whether a probiotic supplement during late pregnancy and breastfeeding can improve health outcomes for babies born to people with gestational diabetes. You may be able to join if you plan to exclusively breastfeed and meet the nutrition, health, and lifestyle criteria.
Minneapolis, MinnesotaAges 21–45 - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06122207Recruiting
Probiotic for women with fertility issues and IVF
This study tests whether a probiotic (a pill with beneficial bacteria) can help improve the health of the female genital tract for people with fertility problems who are undergoing IVF. It aims to see if this can improve chances of pregnancy.
LisbonAges 18–45 - NCT07534033RecruitingPhase 2
Probiotic LR607 for newly diagnosed lung cancer
This study tests whether a probiotic supplement (LR607) can help patients with newly diagnosed non-small cell lung cancer—a common type of lung cancer. Probiotics are beneficial bacteria that may help your immune system fight cancer alongside standard treatments.
GuangzhouAges 18–80 - NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT04788914Recruiting
Test saliva or blood markers to track kidney and leg disease treatment
This study looks at a gene marker (“lncRNA,” a natural molecule in the body) to see how well an oral absorbent, with or without probiotics, is helping people with chronic kidney disease (CKD) who also have blocked leg arteries. It may help doctors better measure treatment impact and tailor care.
Taipei, TaiwanAges 20 years+ - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT06901791Recruiting
Probiotic supplement for gestational diabetes
This trial tests whether taking a probiotic called Lactobacillus Rhamnosus LRa05 can help manage blood sugar levels in women with gestational diabetes. If you've been diagnosed with GDM around 24 weeks of pregnancy, you may be eligible to join.
Suzhou, JiangsuAges 18–50 - NCT06969872Recruiting
Probiotics for Constipation Relief
This trial tests whether taking probiotics can help relieve constipation in adults. If you have chronic constipation but no serious health issues, you may be able to join.
Taichung, SouthAges 18–75 - NCT07189390RecruitingPhase 2
Probiotic study for infants who had antibiotics at birth
This study tests whether giving a probiotic (a 'good' bacteria) to babies who received antibiotics shortly after birth can help their developing gut and immune system. Participants will receive a daily probiotic or placebo for about 6 weeks, and their health will be monitored.
Adelaide, South AustraliaAges Up to 4 weeks - NCT07102836RecruitingPhase 2
Zinc vs probiotics for jaundice in newborns on light therapy
This trial tests whether zinc or probiotics can help babies with jaundice recover faster while receiving phototherapy (light treatment). It aims to find a safe, easy way to lower bilirubin levels.
Bahawalpur, Punjab ProvinceAges birth–4 weeks - NCT07498127Enrolling by invitationPhase 2
Probiotics for colds in young children
This trial tests whether taking probiotics can help young children recover faster from common colds. If your child has a mild or moderate cold and is not taking other probiotics, they may be able to join.
Xuhui, Shanghai MunicipalityAges 3 months–6 years - NCT07590999Recruiting
Probiotics and Menopause Symptoms: A Research Study
This study tests whether taking a probiotic supplement helps with hot flushes, mood changes, and other symptoms of perimenopause (the years around menopause). Researchers believe gut health may play a role in these symptoms.
Oxford, EnglandAges 45–60 - NCT06919913Recruiting
Probiotics for joint infection surgery
This study tests if taking probiotics before and after surgery can help your immune system fight infection in a hip or knee replacement. You would be given a probiotic or a placebo alongside your standard treatment.
New York, New YorkAges 18–90 - NCT06836960Enrolling by invitationPhase 1/Phase 2
Gegen Qinlian Tang and Probiotics for radiation gut issues
This study tests if a traditional Chinese medicine formula (Gegen Qinlian Tang) plus probiotics can help people who have gut problems from radiation treatment for cancer. It may reduce diarrhea, pain, or other bowel symptoms caused by radiation.
Jiujiang, JiangxiAges 18–80 - NCT06544915Recruiting
Synbiotic vs. probiotic for heart and gut health
This study tests whether a synbiotic (a combination of probiotics and prebiotics) is better than a probiotic alone or a placebo for improving gut health and heart health. If you are a healthy adult who hasn't taken antibiotics recently and has few heart disease risk factors, you may be able to join.
Saratoga Springs, New YorkAges 18–60 - NCT07333313Recruiting
Study of oral medicine and probiotics for kidney disease in diabetes
This trial tests if an oral medication that absorbs toxins plus probiotics can reduce inflammation and slow kidney damage in people with diabetes-related kidney disease (DKD). It may help those with mild to severe kidney function loss.
Taipei, TaiwanAges 20 years+ - NCT07212361Recruiting
Restoring infant gut bacteria with mother's microbes
This study tests whether giving healthy newborns a special mix of their own mother's friendly bacteria can help build a healthy gut. It is for mothers who had a healthy pregnancy, plan to breastfeed, and live near Helsinki.
HelsinkiAges Up to 50 years - NCT07200518Recruiting
Probiotics after spine surgery study
This trial tests if taking probiotics after spinal surgery helps recovery. It is for adults with a herniated disc, spinal narrowing, or instability in the lower back or neck.
MariborAges 18 years+
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 224 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.