Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 222 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07135362Recruiting
Probiotic for improving constipation in adults
This trial tests a probiotic supplement to see if it helps improve bowel function in people with constipation. If you have functional constipation (not caused by another illness), this study may be a good fit.
TaipeiAges 18–65 - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT06670807Recruiting
Probiotic supplement for mild memory loss
This study tests whether a probiotic (a supplement with helpful bacteria) can help slow down memory and thinking problems in people with mild cognitive impairment (MCI). It is for adults aged 60–85 who have noticed their memory getting worse over time but can still handle daily activities.
Madrid, MadridAges 65–85 - NCT04362826Recruiting
Trial tests a probiotic to change gut microbes in breast cancer
This study gives a probiotic to see whether it safely changes the gut’s bacteria and fungi (your “microbiome”) in people with breast cancer. The researchers want to learn if this shift in gut microbes might support breast cancer treatment or health during care.
Cleveland, OhioAges 18–65 - NCT04771728RecruitingPhase 4
Probiotics added to treatment for bacterial vaginosis
This study tests whether adding probiotics to standard care helps treat bacterial vaginosis (BV) and possibly lowers the chance of it coming back. You would be placed into a study group to compare probiotic treatment with the other approach.
Shenzhen, GuangdongAges 18–55 - NCT05432479Recruiting
Probiotic study for baby colic crying relief
This trial tests whether a probiotic can reduce symptoms of infantile colic, especially long periods of crying or fussing. If eligible, you’d use a daily crying diary and attend several study visits to see if symptoms improve.
Chicago, IllinoisAges 3 weeks–3 months - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT05652621Recruiting
Probiotics for people with ulcerative colitis symptoms
This study looks at whether probiotic pellets help people with inflammatory bowel disease, specifically ulcerative colitis. It may help improve gut symptoms, but the trial will test how well probiotics work for participants like you.
Xinxiang, HenanAges 18–80 - NCT06030362Recruiting
Probiotic study for weight and gut health in adults
This study tests whether taking a probiotic supplement can help with weight management and gut health in adults with overweight or obesity. You may be able to join if you are between 18 and 50, have a BMI of 25 to 40, and are generally healthy.
Los Angeles, CaliforniaAges 18–50 - NCT06039644Recruiting
Probiotics for breast cancer patients on chemotherapy
This trial tests whether taking a probiotic supplement can help breast cancer patients going through chemotherapy. If you are between 20 and 80 years old, have stage I-III breast cancer, and are receiving certain chemo drugs, this study may be for you.
TaipeiAges 20–80 - NCT06151392RecruitingPhase 4
Probiotics and zinc for children with brain infection
This trial tests whether adding probiotics (healthy bacteria) and zinc supplements to standard treatment helps children with a brain infection called ventriculitis. It aims to see if these supplements improve recovery and reduce complications.
CairoAges 1 month–4 years - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT06317441Recruiting
Probiotic for bloating and high hydrogen breath test
This study tests a probiotic pill for people with bothersome bloating and an abnormal hydrogen breath test. It aims to see if the probiotic helps improve gut symptoms.
Calgary, AlbertaAges 18–65 - NCT06375694Recruiting
Probiotic and nitrate: a blood flow study
This study tests if a probiotic supplement can help your body turn nitrates from food into a substance that may improve blood flow. Healthy adults who are comfortable with blood and saliva samples can take part.
Winston-Salem, North CarolinaAges 18–70 - NCT06385054RecruitingPhase 2
Probiotics for infant colic in breastfed babies
This study tests a probiotic (friendly bacteria) to see if it can reduce crying and fussing in babies with colic. It is for exclusively breastfed infants 8 weeks and younger who have colic symptoms.
Bécon-les-GranitsAges Up to 2 months - NCT06448767Recruiting
Probiotics for autism symptoms in children
This study tests whether a daily probiotic supplement (a mix of good bacteria) can help reduce autism symptoms in children. It lasts 3 months and involves filling out questionnaires about your child's behavior at the start and end of the trial.
Warsaw, WarsawAges 7–15 - NCT06480604Recruiting
Probiotic for yeast infection prevention
This trial tests if taking a multi-strain probiotic daily can prevent repeat yeast infections in women who have had at least three infections in the past year.
Vadodara, GujaratAges 18–50 - NCT06554314Recruiting
Probiotics for gut health and blood fat in adults
This study tests whether taking a probiotic supplement can improve gut health and reduce blood fat levels in adults who are slightly overweight or have high body fat. It may be a good option for people looking for a natural way to support their health.
Taichung, SouthAges 20–65 - NCT06595719Recruiting
Probiotics plus standard care for mild to moderate UC
This trial tests whether adding a multi-strain probiotic supplement to your usual care can help manage mild to moderate ulcerative colitis (UC). It lasts 12 weeks and requires you to stay on your current medications without changes.
Cheras, Kuala LumpurAges 18–90 - NCT06677840Recruiting
Probiotics and the gut-brain connection in autism
This study looks at how the gut and brain are linked in children with autism. It tests whether probiotics can help improve behavior and symptoms by studying the bacteria in the gut.
TaipeiAges 4–15 - NCT05791604Recruiting
Study prebiotics and probiotics to help children with Prader-Willi
This trial studies whether taking prebiotics and probiotics can help children with Prader-Willi syndrome manage obesity. It’s testing a gut-focused approach to weight control over the study period.
Shanghai, Shanghai MunicipalityAges 3–10 - NCT07459699Recruiting
Probiotics for kids with mild ADHD
This study tests whether a probiotic supplement can help children with mild ADHD by improving communication between the gut and the brain. It may offer a natural way to support focus and behavior.
ShanghaiAges 8–11 - NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 222 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.