Clinical trials
Prolapse, Vaginal clinical trials
Below are recruiting prolapse, vaginal clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04701047Recruiting
Study of symptoms in vaginal prolapse patients
This is an observational study that follows women with vaginal prolapse to better understand symptoms and patient experiences. It may help improve future care, even though it does not test a new treatment.
GhentAges 18 years+ - NCT07067645Recruiting
Vaginal length after hysterectomy: comparing two closure methods
This trial compares two ways of closing the vagina after a hysterectomy for severe uterine prolapse to see which method keeps more vaginal length. It may help women who want to preserve vaginal depth after surgery.
IstanbulAges 35–65 - NCT07359755Recruiting
Vaginal vs. robotic mesh surgery for apical prolapse
This study compares two ways to fix a type of pelvic organ prolapse (when organs drop into the vagina): using mesh through vaginal surgery versus using mesh through robotic-assisted abdominal surgery. The goal is to see if the robotic method works as well as the vaginal method.
São Paulo, São PauloAges 18 years+ - NCT03875989Recruiting
Repairing vaginal tissue for front vaginal prolapse
This trial studies a way to repair vaginal tissues to help symptoms of “front” pelvic organ prolapse. It may be an option for people 50+ who can feel or see a bulge and are able to attend follow-up visits.
BordeauxAges 50 years+ - NCT07566949Recruiting
Finnish study comparing uterine prolapse surgery options
This study compares two surgical approaches for women with moderate-to-severe uterine prolapse (when the uterus drops into the vagina). The trial tests whether keeping your uterus during surgery works as well as removing it, with follow-up care over time.
HelsinkiAges 18–100 - NCT06754046Recruiting
Bulking vs. sling for stress incontinence with prolapse repair
This study compares two treatments for stress urinary incontinence (leaking urine when you cough or sneeze) done at the same time as surgery to fix a dropped bladder or uterus. One treatment is a small gel injection (bulking), the other is a sling procedure that supports the urethra.
Cleveland, OhioAges 18 years+ - NCT07218016Recruiting
Recovery After Prolapse Surgery Study
This study tracks how well women recover after surgery for advanced pelvic organ prolapse. You will wear a small activity monitor before and after surgery to see how your activity level changes, and you'll follow a simple exercise plan to help your recovery.
San Diego, CaliforniaAges 18–99 - NCT06902909Enrolling by invitation
Laparoscopic surgery for pelvic organ prolapse
This study tests two types of laparoscopic (keyhole) surgery to repair pelvic organ prolapse, a condition where pelvic organs drop into the vaginal area. One method uses mesh to support the vaginal top, and the other repairs the front or back vaginal wall. It aims to find which approach works best.
SeinäjokiAges 18–79 - NCT06404931RecruitingPhase 2
New material for vaginal prolapse repair
This trial tests a new material made from donated human tissue to repair pelvic organ prolapse. It may help women with certain types of prolapse who have not had prior pelvic surgery.
TerrassaAges 18–100 - NCT07030426RecruitingPhase 3
Vaginal estrogen before and after prolapse surgery
This trial tests whether using vaginal estrogen before and after prolapse surgery helps improve recovery and long-term results. Women having apical suspension surgery (to support the top of the vagina) may benefit.
St. John's, Newfoundland and LabradorAges 18 years+ - NCT05335317Recruiting
Low-intensity laser for vaginal thinning and irritation
This trial studies whether a low-intensity nanosecond laser can improve vaginal atrophy (vaginal thinning) and related symptoms. It may help reduce discomfort for people who fit the study conditions and can complete the required visits and procedures.
Nizhny NovgorodAges 40–75 - NCT07174921Recruiting
Vaginal cuff prolapse repair after hysterectomy
This trial tests a surgery to fix vaginal cuff prolapse (when the top of the vagina drops down) in women who have had a hysterectomy. It may help relieve symptoms and improve quality of life.
Istanbul, IstanbulAges 18 years+ - NCT04378400Enrolling by invitation
Check outcomes after laparoscopic sacrocolpopexy surgery
This study looks at short-term complications and longer-term results after laparoscopic sacrocolpopexy done at the study unit. It may help the clinic understand how well the surgery is working and how to improve care, based on follow-up questionnaires and check-ins.
LeuvenAges Any age - NCT07414849Recruiting
Amniotic membrane to prevent mesh exposure after vaginal surgery
This trial tests if placing a human amniotic membrane over surgical mesh during vaginal repair for pelvic organ prolapse can reduce the risk of the mesh pushing through the vaginal tissue. The study is for women who have not had a hysterectomy and may also have stress urinary incontinence.
Buenos AiresAges Any age - NCT04478747Recruiting
Mesh versus suspension surgery for vaginal prolapse
This trial compares two surgical options to treat a type of vaginal prolapse where the top of the vagina (apical area) has dropped. It may help find which approach works better and has fewer long-term problems for people who’ve had prior prolapse surgery and a hysterectomy.
HelsinkiAges 18–99 - NCT07265973Recruiting
Preparing for recovery after vaginal prolapse surgery
This study tests a program of exercises and education before surgery to see if it helps people recover better after vaginal prolapse repair. It is for people scheduled for specific types of prolapse surgery.
Albuquerque, New MexicoAges 18 years+ - NCT07071818Recruiting
Ultrasound and urine leak after vaginal closure surgery
This study looks at whether a specific ultrasound measurement can predict new urine leakage after a surgery that closes the vagina (colpocleisis) for severe prolapse. It may help women who are not planning future intercourse understand their risk of leaking urine after the procedure.
IstanbulAges 60–75 - NCT05602246Recruiting
Compare two surgeries for vaginal bulging
This trial tests whether one type of vaginal wall repair works better than another surgery for women with vaginal bulging (anterior prolapse). It may help find the safest and most effective operation to reduce symptoms.
Hradec KrálovéAges 50 years+ - NCT04025047Recruiting
Follow-up study after trans-vaginal mesh pelvic surgery
This study follows people who have pelvic reconstructive surgery using a trans-vaginal mesh to learn about possible complications over time. It may help improve care by tracking outcomes for up to 36 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06494982Recruiting
Vaginal flap plus mesh sling for prolapse
This trial tests a surgery that uses a small piece of your own vaginal tissue to help hold the top of the vagina in place with a mesh sling. It is for women who have both front and top vaginal prolapse that bulges outside the opening.
Saint PetersburgAges 45–80 - NCT07517965Recruiting
Vaginal Support Surgery After Hysterectomy
This trial studies a surgical technique to support the vagina after hysterectomy (removal of the uterus) in women with pelvic organ prolapse—when pelvic organs shift downward and may cause pressure or bulging. The goal is to improve comfort and function using the body's own tissues.
AsyutAges Any age - NCT07379411Recruiting
Energy devices vs. cold scalpel for tube and ovary removal during vaginal hysterectomy
This trial is comparing two ways to remove the fallopian tubes and ovaries during a vaginal hysterectomy for pelvic organ prolapse: one using energy-based devices (like a cauterizing tool) and the other using a standard cold scalpel method. It will help determine if the energy-based approach offers any benefits, such as less blood loss or faster recovery.
HolonAges 18 years+ - NCT06024109Recruiting
Comparing two stitches for laparoscopic hysterectomy
This trial compares two types of stitches (SYMMCORA vs. V-Loc) used during laparoscopic hysterectomy to see which one works best. It is for women having planned keyhole removal of the uterus.
Frankfurt am Main, HesseAges 18 years+ - NCT05682989Recruiting
Testing mesh surgery for pelvic organ prolapse symptoms
This trial studies how well and how safely a synthetic mesh surgery works for people with pelvic organ prolapse, especially when it causes bladder or urinary problems. It may help find better symptom relief, but it also tracks side effects closely.
New Taipei CityAges 30–100
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Common questions
- Are there clinical trials for prolapse, vaginal?
- Yes. Clin2 currently lists 24 recruiting prolapse, vaginal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prolapse, vaginal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prolapse, vaginal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.