Clinical trials
Mitral Valve Prolapse clinical trials
Below are recruiting mitral valve prolapse clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03113552Recruiting
How mitral valve bulging location affects long-term repair outcomes
This study looks back at people who had mitral valve repair surgery to see whether the exact location of a valve problem predicts long-term results. It may help doctors better predict outcomes after surgery and plan follow-up care.
Amiens, PicardieAges 18 years+ - NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT05021614Recruiting
Valveclip repair study for leaking mitral valve in older adults
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
SichuanAges 60 years+ - NCT05631730RecruitingPhase 3
Flecainide plus metoprolol vs metoprolol alone for rhythm control
This trial studies whether adding flecainide to metoprolol can better reduce dangerous heart rhythm problems in people with mitral valve prolapse. It also checks safety and side effects compared with metoprolol alone.
OsloAges 18 years+ - NCT06255457Recruiting
Heart rhythm study for patients getting mitral valve surgery
This study looks at heart rhythm problems in people having mitral valve surgery to fix a leaky valve. It may help doctors better understand who is at risk for dangerous rhythms.
Stockholm, Stockholm CountyAges 18 years+ - NCT06341166Recruiting
Predicting heart scarring in mitral valve prolapse
This study looks at people with mitral valve prolapse (a common heart valve condition) to see if doctors can predict who might have scar tissue in their heart muscle. If you have this condition, joining could help improve understanding of your heart health.
Milan, MilanAges 18 years+ - NCT06738537Recruiting
Choosing treatment for mitral valve prolapse
This study looks at how to involve you in decisions about treating mitral valve prolapse, a condition where a heart valve doesn't close tightly. It aims to find the best way to help you and your doctor choose the right treatment.
Los Angeles, CaliforniaAges 21 years+ - NCT07384871Recruiting
3D Ultrasound Study of Mitral Valve Shape and Function
This study uses 3D ultrasound images to better understand heart valve shape and function in people with a leaky mitral valve who are scheduled for valve repair surgery. The goal is to improve how doctors plan and perform the surgery.
San Donato MilaneseAges 18 years+ - NCT06113354Recruiting
Testing the MRace implant for leaky heart valve repair
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
São Paulo, São PauloAges 18 years+ - NCT03962023Recruiting
Study of heart ultrasound features in mitral valve leakage
This study looks at how findings on a standard heart ultrasound (transthoracic echocardiography) can predict outcomes for adults with mitral valve leakage caused by valve prolapse. It may help doctors better understand which ultrasound features matter most, using past and future medical records.
Lomme, NordAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT07103733Recruiting
Adding MRI and monitoring to mitral valve repair study
This study is for people already in the PRIMARY trial who are having mitral valve repair surgery. It adds an extra MRI scan and possibly a heart rhythm monitor to learn more about heart recovery after repair.
Los Angeles, CaliforniaAges 60 years+ - NCT04343313Recruiting
Transcatheter repair for leaky mitral valve in high-risk adults
This pilot study tests a newer catheter-based way to reduce leakage of the mitral valve in people who feel sick from mitral regurgitation but are considered too high-risk for standard surgery. If you fit the valve and heart anatomy needs, the study may help improve symptoms and valve function without open-heart surgery.
New York, New YorkAges 21–95 - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+ - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT03389542Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early versus closely monitoring without surgery in people who have severe leakage but no symptoms. It aims to see whether early repair helps prevent future heart problems.
AmiensAges 18–75 - NCT04733404Recruiting
Dragonfly device study for functional mitral valve leakage
This trial tests a catheter-based procedure (putting a small device through blood vessels) to repair a leaking mitral valve caused by heart muscle problems. It aims to reduce symptoms and improve heart function and safety in people who are still having heart failure symptoms despite standard treatment.
Hangzhou, ZhejiangAges 18 years+
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Common questions
- Are there clinical trials for mitral valve prolapse?
- Yes. Clin2 currently lists 19 recruiting mitral valve prolapse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mitral valve prolapse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mitral valve prolapse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.