Clinical trials
Prostate cancer clinical trials
Cancer of the prostate gland, one of the most common cancers in men. We’re tracking 1,212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07578519RecruitingPhase 2
Personalized Radiation Therapy for Intermediate to High-Risk Prostate Cancer
This trial tests a new type of radiation therapy that is customized for each patient's prostate cancer. The radiation targets the tumor more precisely, which may help reduce side effects while treating the cancer effectively.
Lethbridge, AlbertaAges 18 years+ - NCT07694752Recruiting
MRI study of prostate and urinary sphincter
This study uses special MRI scans to look at the muscle ring that controls urination and the base of the prostate. It may help doctors understand how these areas change with conditions like enlarged prostate or prostate cancer treatment.
Taizhou, JiangsuAges 15–90 - NCT06813898RecruitingEarly Phase 1
A New Scan for Early Prostate Cancer Recurrence
This study tests a new scanning method (rhPSMA-7.3 PET/CT) to detect prostate cancer recurrence when PSA is slightly high. If your PSA is low but rising, and standard scans haven't found cancer, this scan might help locate it.
Chicago, IllinoisAges Any age - NCT06116019Recruiting
Online adaptive radiotherapy for cancer patients
This trial tests a new radiation therapy machine that adjusts the radiation plan in real-time based on changes in your body. It may help make treatment more precise and reduce side effects.
BerlinAges 18 years+ - NCT04254133Enrolling by invitation
Study uses genetics to guide prostate cancer care and screening
This study collects saliva and health/family history information to learn how inherited (genetic) factors relate to prostate cancer. The goal is to improve how treatment and future screening are planned for people and families.
Seattle, WashingtonAges 35–89 - NCT07316686RecruitingPhase 1
Study of docetaxel and lutetium-PSMA for first-line treatment of metastatic prostate cancer
This trial tests a combination of chemotherapy (docetaxel) and a targeted radiation therapy (lutetium-PSMA) as a first treatment for men whose prostate cancer has spread and no longer responds to hormone therapy. The goal is to see if this combination is safe and effective.
São PauloAges 18 years+ - NCT05610852Recruiting
Surgery through the bladder opening versus focused ultrasound for prostate cancer
This trial compares two ways to treat early prostate cancer: a single small surgery through the bladder versus high-intensity focused ultrasound (HIFU). It aims to see which approach works better while keeping side effects and recovery acceptable.
Cleveland, OhioAges 19 years+ - NCT06011499Recruiting
Online lifestyle program for prostate cancer survivors
This study tests an internet-based program to help prostate cancer survivors who are overweight and frail improve their health. You will be assigned to either a lifestyle coaching group or a usual care group, and both groups are followed for about 6 months.
Portland, OregonAges 18 years+ - NCT07189871RecruitingPhase 1/Phase 2
Targeted radiation therapy for advanced solid tumors
This study tests a new radioactive treatment (177Lu-BetaBart) for people with certain advanced solid tumors that have stopped responding to standard treatments. It aims to see if this targeted therapy can slow or stop tumor growth.
Dothan, AlabamaAges 18 years+ - NCT06389097Recruiting
SPECT Scans to Improve Treatment for Advanced Cancer
This study uses special scans (SPECT imaging) to see how radium or lutetium treatments move through your body, helping doctors plan better doses. It's for people with advanced prostate cancer (getting Radium-223) or advanced neuroendocrine tumors (getting 177Lu treatments).
Baltimore, MarylandAges 18–100 - NCT04831983Recruiting
Radiation treatment for intermediate- and high-risk prostate cancer
This trial studies a type of focused radiation (“ablative radiotherapy”) for prostate tumors considered intermediate- or high-risk. It may help improve control of the cancer while aiming for acceptable side effects.
Monza, MBAges 18–90 - NCT06204341Recruiting
Finding the best radiation for high-risk prostate cancer
This trial compares different radiation therapy plans for men with high-risk prostate cancer that has spread to the lymph nodes. It aims to find the best way to treat the prostate and the surrounding lymph nodes while minimizing side effects.
Leidschendam, South HollandAges 18 years+ - NCT07740239Recruiting
Study on frailty in seriously ill adults
This study looks at why some seriously ill adults become frail. It involves imaging and other tests to help doctors better understand and care for patients with serious conditions.
TampereAges Any age - NCT07721935Recruiting
AI tool for urological disease diagnosis and treatment
This trial is testing an artificial intelligence (AI) system that helps doctors diagnose and treat urological conditions like urinary stones, prostate cancer, or bladder cancer. It looks at your medical records, scans, and surgical videos to improve care.
Guangzhou, GuangdongAges Any age - NCT06274892Recruiting
Using an app to improve radiotherapy check-ins
This study tests whether using a mobile app to report symptoms during radiation treatment helps doctors better support patients. It is for people with breast or prostate cancer starting radiation therapy at Princess Margaret Cancer Centre.
Toronto, OntarioAges 18 years+ - NCT06863090Recruiting
Study measuring radiation dose during brachytherapy
This trial tests a way to measure the exact radiation dose you receive during internal radiotherapy (brachytherapy). It aims to make treatment safer and more effective for prostate or gynecologic cancers.
Northwood, MiddlesexAges 18 years+ - NCT07218666RecruitingPhase 2
Zanzalintinib for aggressive prostate cancer
This trial tests a new drug, zanzalintinib, in men with a fast-growing type of prostate cancer that has spread and stopped responding to standard hormone therapies. It aims to see if the drug can help shrink tumors or slow the disease.
Milwaukee, WisconsinAges 18 years+ - NCT07132073Enrolling by invitation
MRI-guided SBRT for high-risk prostate cancer
This study tests a precise radiation treatment for prostate cancer that uses MRI images to guide the radiation beams. It may be an option for men with higher-risk prostate cancer who can have an MRI and have not had radiation before.
Pamplona, Foral Community of NavarreAges 18–80 - NCT05805436RecruitingPhase 4
Laxatives before robotic prostate or kidney surgery
This trial tests whether giving a laxative before certain robotic urologic surgeries improves bowel function after surgery. It may help reduce constipation and related discomfort during recovery.
Iowa City, IowaAges 30–100 - NCT06825715Recruiting
Precision oncology support for lung and prostate cancer
This study tests a program to help veterans with lung or prostate cancer get personalized cancer treatments. The goal is to see if extra support for doctors and patients leads to better use of precision medicine.
New York, New YorkAges Any age - NCT06511141Recruiting
Nerve stimulation for men with overactive bladder
This study tests a nerve stimulation device placed near the tailbone to help men with overactive bladder symptoms. If you have bothersome urinary urgency or frequency, this treatment may offer relief without drugs.
Birmingham, AlabamaAges 18 years+ - NCT06499870RecruitingPhase 2
Study of two drugs with radiation for high-risk prostate cancer
This trial tests whether combining two hormone therapy drugs, relugolix and enzalutamide, with radiation therapy can help treat very high-risk prostate cancer. The goal is to see if this combination is safe and effective for men whose cancer has a high chance of coming back.
Chicago, IllinoisAges 18 years+ - NCT06112990RecruitingPhase 3
Creatine and exercise to keep muscles strong in prostate cancer
This trial tests if taking creatine plus doing resistance exercises at home can help men with prostate cancer maintain muscle mass and slow cancer growth. You would take creatine or a placebo for 52 weeks and do simple strength exercises twice a week.
Salt Lake City, UtahAges 18 years+ - NCT06067295Recruiting
Long-term study of advanced prostate cancer
This study follows men with advanced prostate cancer that has spread to other parts of the body. It aims to learn more about how the disease and treatments affect patients over time, so doctors can improve care.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for prostate cancer?
- Yes. Clin2 currently lists 1,212 recruiting prostate cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.