Clinical trials
Prostate Disease clinical trials
Below are recruiting prostate disease clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06526299RecruitingPhase 2
Higher dose of targeted radiation for prostate cancer with low PSMA levels
This trial tests a higher dose of a radioactive drug (177Lu-PSMA-617) for men whose prostate cancer has spread and does not produce much of a protein called PSMA on scans. The goal is to see if a stronger dose can work better than the standard dose.
San Francisco, CaliforniaAges 18 years+ - NCT06072911Recruiting
Men's health after prostate cancer surgery study
This study looks at how men recover control of urine and sexual function after prostate removal surgery. It also tests if a 12-week exercise program can help improve these functions.
Edmonton, AlbertaAges 18 years+ - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT04692675Recruiting
MRI study to track prostate cancer in active surveillance patients
This study uses special prostate MRI scans to see how prostate cancer changes over time while you stay on active surveillance. It also looks at prostate tissue to understand your cancer’s genetics, which may help guide future decisions.
Bethesda, MarylandAges 18 years+ - NCT06237179RecruitingPhase 1/Phase 2
Exercise program to reduce heart risk in prostate cancer
This study tests whether a supervised exercise program can help reduce heart disease risk in men with prostate cancer who are on hormone therapy. Participants will exercise at home or in a group and be monitored for heart health changes.
Richmond, VirginiaAges 40–85 - NCT05570994Enrolling by invitationPhase 1/Phase 2
PSMA-targeted radioactive drug for advanced prostate cancer
This Phase 1/2 study tests a radioactive treatment that targets PSMA, a protein often found on prostate cancer cells. It’s for men whose prostate cancer has worsened despite hormone-blocking pills like abiraterone or enzalutamide, aiming to help shrink or control the disease.
Vancouver, British ColumbiaAges 18 years+ - NCT04472338Recruiting
Prostate cancer screening for people with higher genetic risk
This study looks at prostate cancer screening for people who may be at higher risk because of a specific inherited (genetic) change. It may help your care team find the best screening approach to catch aggressive prostate cancer earlier.
Duarte, CaliforniaAges 40 years+ - NCT06927635RecruitingPhase 2
SBRT vs standard care for prostate cancer that has spread to a few spots
This trial tests whether targeted radiation (SBRT) to a few sites of cancer spread can help men whose prostate cancer has stopped responding to hormone therapy but has not spread to many places. You may benefit if you have a limited number of growing spots outside the brain or spine.
Toronto, OntarioAges 18–100 - NCT06832774RecruitingPhase 2
Hormone therapy plus local treatment for advanced prostate cancer
This study tests adding a targeted local treatment (like radiation or surgery) to standard hormone therapy for men with advanced prostate cancer that still shows up on a special scan. The goal is to see if this combination helps control the cancer better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06682390Recruiting
Race and diet study for men on hormone therapy
This study explores how race affects nutrition for men receiving hormone therapy (ADT) for prostate cancer. It may help researchers understand if different dietary approaches are needed based on race.
Los Angeles, CaliforniaAges 18 years+ - NCT06992232RecruitingPhase 2
Radiation or surgery plus hormone therapy for prostate cancer that has spread
This trial tests whether giving intense hormone therapy along with either radiation or surgery can help men with prostate cancer that has spread to a limited number of spots (10 or fewer) but not to organs like the liver or lungs. The goal is to treat both the main tumor and the visible metastatic spots more aggressively.
Nanjing, JiangsuAges 18–80 - NCT06202820Recruiting
Heart health monitoring for men on hormone therapy
This study checks how men starting hormone therapy (ADT) for prostate cancer are doing with their heart health. It offers follow-up visits at the cancer center to track blood pressure and lab results, with the goal of catching any heart-related issues early.
Boston, MassachusettsAges 18 years+ - NCT06470685Enrolling by invitation
Preventive prostate removal for prostate cancer risk
This study tests whether removing the prostate before cancer develops can help people at higher risk, such as those with certain gene changes (like BRCA2), a strong family history, or Black African/Caribbean ancestry. It also includes people who have already had their prostate removed for cancer treatment.
LondonAges 18 years+ - NCT06831032Recruiting
Adaptive radiation for prostate cancer in lymph nodes
This trial tests a type of targeted radiation (SBRT) for prostate cancer that has come back only in certain lymph nodes around the belly or hip. The goal is to see if adapting the radiation plan during treatment can make the response last longer.
Toronto, OntarioAges 18 years+ - NCT05201131Recruiting
Study of Rezūm treatment for enlarged prostate in Canadian patients
This study looks at outcomes from the Rezūm procedure for men with an enlarged prostate (BPH). You may be asked to complete questionnaires and follow the study plan to help researchers understand how well this treatment works and is tolerated.
Toronto, OntarioAges 18 years+ - NCT07334275Recruiting
Detecting leftover cancer cells after prostate removal
This trial tests a new way to find microscopic cancer cells (minimal residual disease) in the blood after prostate surgery. If successful, it could help doctors decide if additional treatment is needed.
NijmegenAges 18 years+ - NCT05169892Recruiting
Aquablation treatment study for enlarged prostate in Canada
This trial studies how well Aquablation works for men with an enlarged prostate (BPH) in Canada. You may be eligible if your clinician believes Aquablation is an appropriate treatment and you can complete the study visits and questionnaires.
Toronto, OntarioAges 18 years+ - NCT06357416Recruiting
Man Van project: mobile cancer screening for men
This study collects information from men who visit the Man Van, a mobile health clinic that screens for cancers like prostate, testicular, and penile cancers. It aims to learn how well the clinic works and how it can help men catch cancer early.
LondonAges 18 years+ - NCT06720532Recruiting
Kidney function in men with prostate cancer getting a new targeted radiation therapy
This study looks at how a targeted radiation therapy called 177Lu-PSMA affects kidney function in men with a type of advanced prostate cancer. It aims to understand risk factors to help guide safe treatment.
MunichAges 18 years+ - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT07721935Recruiting
AI tool for urological disease diagnosis and treatment
This trial is testing an artificial intelligence (AI) system that helps doctors diagnose and treat urological conditions like urinary stones, prostate cancer, or bladder cancer. It looks at your medical records, scans, and surgical videos to improve care.
Guangzhou, GuangdongAges Any age - NCT04625556Recruiting
Urology cancer registry study using body microbiome data
This study builds a patient registry for prostate, kidney, bladder, and ureter cancers by analyzing your body’s microbiome (the microbes living in/ on the body). It may help doctors personalize care in the future, and your participation mainly involves allowing your medical and related information to be used for research.
SeoulAges 20 years+ - NCT06225479Recruiting
Exercise for older men with urinary problems
This study tests whether a special exercise program can help older men with urinary symptoms from an enlarged prostate. You'll either exercise at home with a heart rate monitor or receive health education for 6 months.
San Francisco, CaliforniaAges 60 years+
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Common questions
- Are there clinical trials for prostate disease?
- Yes. Clin2 currently lists 65 recruiting prostate disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.