Clinical trials
Psychological Distress clinical trials
Below are recruiting psychological distress clinical trials, each written for real people, not researchers. We’re tracking 78 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06638450Recruiting
Acupuncture for Teens with Stress and Insomnia
This study tests whether acupuncture can help teenagers who have been feeling anxious or down and having trouble sleeping. If you've had these feelings for more than 3 months and haven't taken medicine or had acupuncture recently, you may be able to join.
Hong Kong, Hong KongAges 15–22 - NCT06606249Recruiting
Self-help coping skills for stressed university students
This trial tests a self-guided program, Self-Help Plus, to help university students manage stress and catch up with their studies. It may be helpful if you are behind on exams and feeling distressed.
Bari, BariAges 18 years+ - NCT07335302Recruiting
Study to improve comfort during brachytherapy device removal
This study looks at improving comfort and reducing distress when removing the internal device used in brachytherapy (a type of radiation) for gynecologic cancer. You will be asked to fill out surveys about how you feel before, during, and after the removal.
Houston, TexasAges 18 years+ - NCT05503485Recruiting
Group or phone support for older adults with distress
This study tests whether structured group therapy, or supportive phone calls, can help older adults (75+) who feel increased psychological distress. You may be placed in a group session or offered phone support, and the study will compare your experience and outcomes.
GothenburgAges 75 years+ - NCT07644949Recruiting
Stress-Reduction Program for Social Service Workers
This study tests whether a self-help program called Self-Help Plus can reduce stress and improve well-being in social service workers. You would attend sessions and complete questionnaires over the study period.
IstanbulAges 18 years+ - NCT06218901Recruiting
Psychological distress in lung cancer patients
This study looks at how lung cancer patients experience emotional distress like anxiety or depression. It aims to better understand these feelings and how they affect patients so that support can be improved.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07209306Recruiting
Psychological help for migrants in Italy: The ADVANCE trial
This trial tests two WHO-designed psychological programs (called SH+ and DWM) to help migrants in Italy cope with stress, anxiety, and depression. You will be randomly assigned to one of the programs to see if they improve your mental health and well-being.
Verona, ItalyAges 18 years+ - NCT07063862RecruitingPhase 3
Psychedelic microdose for emotional distress in advanced illness
This trial tests whether very low doses of psilocybin (a psychedelic substance) can help reduce emotional distress in people with a life-limiting illness. If you are receiving palliative care and feeling anxious or depressed, this study might offer a way to explore a new treatment option.
Brampton, OntarioAges 18 years+ - NCT07193329Recruiting
Stress and cancer treatment: How emotions affect your care
This study looks at how stress and emotional distress can affect cancer patients' ability to stick with their treatment plan, their treatment results, and their overall quality of life. It aims to help doctors better understand and support patients.
Wenzhou, ZhejiangAges 18 years+ - NCT07654569Recruiting
Mental health help for university students online
This study tests an online program to help university students feel better mentally. It uses a type of therapy called ACT to teach useful skills for handling stress and emotions.
Bologna, BOAges 18 years+ - NCT06518616RecruitingPhase 2
Meditation app for firefighters to reduce stress
This study tests if a meditation app can help firefighters feel less stressed or distressed. You'll use a smartphone app to practice meditation and see if it helps you feel better.
Tucson, ArizonaAges 18 years+ - NCT07257848Recruiting
Psychotherapy study from Ecuador mental health services
This study looks at how well psychological therapy works in real-life settings in Ecuador. It examines the experiences of clients, therapists, and supervisors to find what helps or hinders progress.
Quito, (P)PichinchaAges 11 years+ - NCT04475354Recruiting
Questionnaire study of distress in cervical cancer patients and partners
This study asks newly diagnosed cervical cancer patients and their partners to complete questionnaires about distress (emotional stress and worry). It may help researchers understand how distress affects both patients and partners and what support could be most helpful.
BredaAges 18 years+ - NCT07677527Recruiting
Post-traumatic growth support for emergency nurses
This study tests a program to help nurses in emergency units cope with stressful experiences and grow from them. It might be helpful if you've been through difficult events at work and want support.
MultanAges Any age - NCT05459896Recruiting
Health app program for distress, fatigue, pain, and poor sleep
This trial tests whether a smartphone health app can help adults who are struggling with psychological distress (like high stress), physical fatigue, pain, and/or poor sleep after the pandemic. You may qualify if your answers on screening questionnaires show enough distress, and you can use a smartphone and the internet.
Hong KongAges 18–70 - NCT06776523Recruiting
Psychological help study for refugees in Switzerland
This study tests a brief psychological program (Problem Management Plus, or PM+) to see if it helps refugees and asylum seekers feel better. If you are feeling stressed, anxious, or down, this may be an option for you.
ZurichAges 16 years+ - NCT07415915Enrolling by invitation
Heart rate biofeedback for stress in dentistry students
This trial tests if a technique called heart rate variability biofeedback (HRVB) can help reduce stress and anxiety in students moving from classroom to clinical training. It may be a good fit if you are a 4th-year dentistry student starting clinical work.
Almada, Setúbal DistrictAges 18 years+ - NCT07386951Recruiting
Heart rate biofeedback for security force personnel
This trial tests whether a biofeedback technique that improves heart rate control can help military personnel manage stress and perform better in their duties. You would learn a simple relaxation method while on active duty.
SetúbalAges 18–55 - NCT06937021Enrolling by invitation
Art and philosophy program for kids' eco-anxiety
This trial tests whether an art and philosophy program can help elementary school children manage their eco-anxiety. If your child is in elementary school, they may be able to join.
Henhurst Ridge, Burton-on-TrentAges 5–12 - NCT06436456Recruiting
Online program for diabetes distress in type 1 diabetes
This trial tests an online program to help adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes (called diabetes distress). The program is designed to reduce that distress and make living with diabetes a bit easier.
OdenseAges 30 years+ - NCT07692269Recruiting
Mindfulness for emotional distress study
This study tests whether mindfulness can help reduce emotional distress. You will practice mindfulness and have your brain activity measured with EEG, a safe and painless way to record brainwaves.
Beijing, Beijing MunicipalityAges 18–50 - NCT06627140Recruiting
Preterm birth, parent stress, and child mental health
This study follows up on families who were already in an earlier research project about preterm birth. It looks at how parents' stress during pregnancy and after birth might affect their child's mental health as they grow up.
Frankfurt am Main, HesseAges Any age - NCT06908343Recruiting
Expectations and Distress in Mental Health Patients and Their Therapists
This study looks at how your expectations about therapy affect your distress and how your therapist's expectations play a role. It may help improve treatment for people like you at Shalvata.
IsraelAges Any age - NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+
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Psychological Distress trials by city
Studies with a site in or near these metro areas.
Psychological Distress trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for psychological distress?
- Yes. Clin2 currently lists 78 recruiting psychological distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychological distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychological distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.