Clinical trials
Psychological Distress clinical trials
Below are recruiting psychological distress clinical trials, each written for real people, not researchers. We’re tracking 79 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+ - NCT07141056Recruiting
Emotional stress and immunotherapy for liver cancer
This study looks at how emotional stress affects how well immunotherapy works for liver cancer. It is for people with liver cancer who are about to start immunotherapy, either before or after surgery, or as first treatment for advanced cancer.
Zhanjiang, GuangdongAges 18 years+ - NCT04900064Recruiting
Self-help CBT added to primary care behavioral health
This trial studies whether adding a Swedish self-help version of “CBT” (a structured talking-therapy approach) improves care for adults getting behavioral health support in primary care. It may help people who want support for mental health without needing fully guided therapy sessions.
Varberg, Halland CountyAges 18 years+ - NCT07562100Recruiting
AI-Powered Exercise Program for Oral Cancer Patients Returning to Work
This study tests a smartphone-based exercise and wellness program designed to help people recently diagnosed with oral cancer prepare their body and mind before treatment, with the goal of helping them return to work faster and more safely. Researchers will track whether the program improves recovery and reduces healthcare costs.
TaipeiAges 20–70 - NCT07392437Recruiting
Study on diabetes distress in type 2 diabetes patients
This study looks at the emotional stress related to managing type 2 diabetes, known as diabetes distress. The goal is to understand how common it is and what factors may contribute to it.
NiceAges 18 years+ - NCT07501637Recruiting
Mind-body group support for young breast cancer survivors
This study tests a mind-body group program to help young breast cancer survivors manage stress and emotional distress. It includes a virtual workshop, weekly group sessions, and daily practices to improve well-being.
Birmingham, AlabamaAges 18–50 - NCT07871916Recruiting
Mindfulness app for parents going through divorce or separation
This study tests a mindfulness app designed to help parents manage stress during divorce or separation. It may help you feel calmer and more focused as you navigate this challenging time.
Stamford, ConnecticutAges 18 years+ - NCT07768540Recruiting
Trauma counseling for school students
This study tests a school-based counseling program that helps teenagers cope with traumatic experiences. It aims to reduce stress and improve mental health for students who have been through a difficult event.
IslamabadAges 10–16 - NCT07765355Recruiting
Virtual nature for anxiety in hospitalized older adults
This trial tests whether watching virtual nature scenes or guided imagery can help reduce anxiety and improve well-being in older adults while they are in the hospital. It may offer a calming, drug-free way to support your mental health during a hospital stay.
BudapestAges 65 years+ - NCT07722949Recruiting
A nurse-led program for caregivers of children with autism
This study tests a culturally adapted program where nurses help caregivers build skills to support a child with autism. It aims to reduce stress and improve well-being for both the caregiver and the child.
Faisalābad, Punjab ProvinceAges 18 years+ - NCT07672314Recruiting
Psychosocial support study for cancer survivors
This study tests a program to help cancer survivors manage emotional and social challenges after treatment. You may be able to join if you have completed your main cancer treatment and are now in routine follow-up care.
BaselAges 18 years+ - NCT06197711Recruiting
PRISMA for mental health in pretrial detention
This study tests whether a program called PRISMA can help improve mental health for people in pretrial detention. It is designed for detainees in Zurich and Bern who speak one of nine languages and are not in immediate crisis.
Zurich, Canton of ZurichAges 18 years+ - NCT07639697Recruiting
Stress Training via Phone for Young Adults
This study tests a phone-based program to help young adults (ages 18–30) manage stress. You'll use a smartphone app and wear a small monitor for 14 days to see if guided training can help you feel better.
Pittsburgh, PennsylvaniaAges 18–30 - NCT05308537Recruiting
Mindful compassion program for nurses feeling emotionally exhausted
This study tests whether a mindful compassion training program can reduce psychological distress in nurses who feel emotionally drained. It targets nurses working on COVID-19 hospital units and compares the program to a wait-and-see group.
Verona, ItaliaAges 25–65 - NCT07617467Recruiting
Group therapy for emotional distress in young people
This trial tests whether group-based therapy (Acceptance and Commitment Therapy, or ACT) can help young people manage anxiety, depression, and stress. The therapy teaches skills to accept difficult feelings while living according to your values.
Arendal, AgderAges 16–25 - NCT07615257Recruiting
Mindfulness and CBT for Psoriasis-Related Emotional Stress
This study tests whether a combination of mindfulness and cognitive behavioral therapy (CBT)—talk-based techniques to manage thoughts and emotions—can help psoriasis patients feel less stressed and more compassionate toward themselves. Participants attend sessions over several weeks to learn these skills.
Rahim Yar Khan, Punjab ProvinceAges 25–75 - NCT07594756Recruiting
Online social support while waiting for mental health care
This trial tests an online platform that offers social support and activities for young people aged 16 to 25 who are waiting for mental health care. It may help reduce distress and make the waiting period easier.
AmsterdamAges 16–25 - NCT07550166Enrolling by invitation
Mindfulness App Study for Korean Older Adults
This study tests whether a mindfulness app—guided exercises to help you relax and focus your mind—can improve wellbeing in Korean immigrants aged 60 and older. You'll use the app on your smartphone for 8 weeks.
Tampa, FloridaAges 60 years+ - NCT07506525Recruiting
Flourish in Schools pilot study
This study tests a program called Flourish that uses text messages to help students who have experienced cyberbullying and may be feeling distressed or having thoughts of suicide. It aims to see if the program is helpful for teens and young adults.
Bay Village, OhioAges 11–21 - NCT07481890Recruiting
EMDR therapy for cancer patients
This trial tests a short therapy method (EMDR toolbox) to help cancer patients cope with emotional distress. It may reduce anxiety and improve well-being.
Bellinzona, Canton TicinoAges 18–65 - NCT05570734Recruiting
Study of diabetes support for Hispanic/Latino adults online
This study looks at an online (e-health) way to help adults with type 2 diabetes better follow their diabetes care plan. It targets Hispanic/Latino patients and may help improve how consistently people manage their diabetes.
Chula Vista, CaliforniaAges 18 years+ - NCT05667857Recruiting
Tracking brain, mood, and quality of life after immunotherapy
This study follows people who have had advanced cancer and are now stable after immunotherapy, to see how thinking, mood, and daily life change over time. Some participants may also do an integrative brain-training program if they have memory or thinking problems.
Brussels, Brussels CapitalAges 18 years+ - NCT04829877Recruiting
Study stress changes in women trying to get pregnant
This study follows how emotional distress changes over time in women who are starting infertility treatment and trying to conceive. It may help researchers understand what support might be most helpful during the start of fertility care.
TaipeiAges 20–60 - NCT04981730Recruiting
Online childbirth and parenting classes for first-time parents
This study tests a web-based program that teaches first-time mothers and fathers (and their support partners) about childbirth and parenting during pregnancy. It may help you feel more prepared by giving daily, online guidance tailored to first-time parents.
TaipeiAges 20–60
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Common questions
- Are there clinical trials for psychological distress?
- Yes. Clin2 currently lists 79 recruiting psychological distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychological distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychological distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.