Clinical trials
Psychological Distress clinical trials
Below are recruiting psychological distress clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06435208Recruiting
Gum cleaning for mental health in teeth grinders with gum disease
This study tests whether a deep gum cleaning procedure (subgingival instrumentation) can reduce stress and improve mental health in people who grind their teeth and have gum disease. It aims to see if treating the gums can also help with psychological distress.
Rohtak, HaryanaAges 30–50 - NCT07392437Recruiting
Study on diabetes distress in type 2 diabetes patients
This study looks at the emotional stress related to managing type 2 diabetes, known as diabetes distress. The goal is to understand how common it is and what factors may contribute to it.
NiceAges 18 years+ - NCT06575673Recruiting
Online skills training to help smokers quit and feel better
This trial tests an internet-based program that teaches skills to help you quit smoking and manage stress, anxiety, or low mood. You'll use your own device to get support and learn new ways to cope.
Tai Po, New TerritoriesAges 18–64 - NCT05676255RecruitingPhase 2
SUPORT study for breast cancer survivors and their partners
This Phase 2 study looks at an online program for breast cancer survivors and their supportive partners who live together. The goal is to see whether the program helps survivors and partners during survivorship and adjustment after treatment.
Tucson, ArizonaAges 18 years+ - NCT05755178Enrolling by invitation
Music group program for children living in shelters
This study tests a music group intervention for children who live in shelters with a caregiver. It may help improve kids’ well-being through shared, structured group activities.
VaxjoAges 3–10 - NCT05436106Recruiting
Reducing stress with a behavioral program for Black gender minority women
This trial tests a behavior-based program meant to help lower stress. It is designed for Black gender minority women who were assigned male at birth.
Atlanta, GeorgiaAges 18–99 - NCT04829877Recruiting
Study stress changes in women trying to get pregnant
This study follows how emotional distress changes over time in women who are starting infertility treatment and trying to conceive. It may help researchers understand what support might be most helpful during the start of fertility care.
TaipeiAges 20–60 - NCT04981730Recruiting
Online childbirth and parenting classes for first-time parents
This study tests a web-based program that teaches first-time mothers and fathers (and their support partners) about childbirth and parenting during pregnancy. It may help you feel more prepared by giving daily, online guidance tailored to first-time parents.
TaipeiAges 20–60 - NCT07506525Recruiting
Flourish in Schools pilot study
This study tests a program called Flourish that uses text messages to help students who have experienced cyberbullying and may be feeling distressed or having thoughts of suicide. It aims to see if the program is helpful for teens and young adults.
Bay Village, OhioAges 11–21 - NCT06002191Recruiting
A text-based safety program for teens bullied online
This study tests a texting program called imHere4U to help teens who have been cyberbullied and feel distressed or think about suicide. The program aims to provide support and reduce suicide risk.
Pittsburgh, PennsylvaniaAges 12–17 - NCT07195019Recruiting
Women's Wellbeing Study for survivors of violence
This study tests whether a specially-designed yoga program can help women who have experienced interpersonal violence feel better. You would participate in yoga sessions and assessments to see if it reduces distress.
Providence, Rhode IslandAges 18–65 - NCT07639697Recruiting
Stress Training via Phone for Young Adults
This study tests a phone-based program to help young adults (ages 18–30) manage stress. You'll use a smartphone app and wear a small monitor for 14 days to see if guided training can help you feel better.
Pittsburgh, PennsylvaniaAges 18–30 - NCT06279013Recruiting
Phone check-ins to manage symptoms during oral cancer treatment
This study tests two ways of using telephone check-ins to help people manage side effects and emotional distress while taking oral anti-cancer pills at home. If you are starting or recently started an oral anti-cancer drug, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT06941324Recruiting
Therapy to help teens and young adults with cancer feel better
This study tests a short-term therapy called Solution-Focused Brief Therapy to help teens and young adults with cancer reduce emotional distress. It's designed for people who are currently in treatment or have finished treatment within the last 5 years.
Ann Arbor, MichiganAges 15–39 - NCT06878092Recruiting
A support program for young refugees with emotional distress
This trial tests a program called Problem Management Plus with Emotional Processing (PM+EP) for youth who were forced to leave their home country. It aims to reduce stress and improve daily functioning. If you are a young refugee between 16 and 25 years old and feel very anxious or down, this might help you learn ways to cope.
StockholmAges 16–25 - NCT07136948Recruiting
Mindfulness plus body-sensor training for stress relief
This study tests whether mindfulness training paired with a special shirt that tracks your breathing and heart rate can help reduce stress. You'll be assigned to one of two groups and give feedback on your experience.
Pittsburgh, PennsylvaniaAges 18–30 - NCT07722949Recruiting
A nurse-led program for caregivers of children with autism
This study tests a culturally adapted program where nurses help caregivers build skills to support a child with autism. It aims to reduce stress and improve well-being for both the caregiver and the child.
Faisalābad, Punjab ProvinceAges 18 years+ - NCT06979089Recruiting
Stress relief program for Dutch SMEs
This trial tests an online stress-management program for employees in small to medium-sized businesses in the Netherlands. It aims to help people with high stress levels feel better and cope more effectively.
Amsterdam, North HollandAges 18 years+ - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT05308537Recruiting
Mindful compassion program for nurses feeling emotionally exhausted
This study tests whether a mindful compassion training program can reduce psychological distress in nurses who feel emotionally drained. It targets nurses working on COVID-19 hospital units and compares the program to a wait-and-see group.
Verona, ItaliaAges 25–65 - NCT05570734Recruiting
Study of diabetes support for Hispanic/Latino adults online
This study looks at an online (e-health) way to help adults with type 2 diabetes better follow their diabetes care plan. It targets Hispanic/Latino patients and may help improve how consistently people manage their diabetes.
Chula Vista, CaliforniaAges 18 years+ - NCT05667857Recruiting
Tracking brain, mood, and quality of life after immunotherapy
This study follows people who have had advanced cancer and are now stable after immunotherapy, to see how thinking, mood, and daily life change over time. Some participants may also do an integrative brain-training program if they have memory or thinking problems.
Brussels, Brussels CapitalAges 18 years+ - NCT05713617Recruiting
Health program for Latino families raising kids with disabilities
This study tests a family health promotion program for Latino caregivers of children ages 6 to 17 who have an intellectual or developmental disability. It may help by teaching practical ways to support health and well-being at home.
Chicago, IllinoisAges 6–100 - NCT05722236Recruiting
Peer support program to help people manage stress from IBD
This trial tests a “peer-to-peer” support program to help adults with inflammatory bowel disease (IBD) manage psychological distress (stress and emotional strain). It may help you cope better during major life or treatment changes related to IBD.
Halifax, N.S.Ages 18–99
Hear when a new Psychological Distress trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for psychological distress?
- Yes. Clin2 currently lists 74 recruiting psychological distress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychological distress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychological distress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.