Clinical trials
Psychosis clinical trials
Below are recruiting psychosis clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06608706Recruiting
Integrated trauma treatment for psychosis
This trial tests a new way to treat trauma in people who have psychosis (like schizophrenia). It combines therapy for trauma with your usual care, and aims to help you feel less distressed by past traumatic events.
BergenAges 16 years+ - NCT06634446Recruiting
Self-guided cognitive training for early psychosis
This study tests a self-guided cognitive training program designed for young people who recently had their first episode of psychosis. It aims to improve thinking skills and daily function through exercises you can do at home.
ParisAges 16–35 - NCT06650943Recruiting
Nursing help for weight and metabolic health in early psychosis
This study tests a nursing program to help people with early psychosis manage weight and reduce the risk of metabolic syndrome (a cluster of conditions that raise heart disease risk). It's designed for people who have had their first psychotic episode within the last 5 years.
Bilbao, VizcayaAges Any age - NCT06728241Recruiting
Virtual reality and AI therapy for psychosis
This study tests if virtual reality and artificial intelligence can help people with psychosis overcome difficulties going outside or doing everyday activities. It uses VR scenarios and AI tools to support treatment.
Oslo, NorwayAges 17–65 - NCT06774417Recruiting
Digital strategies to help young people seek help for mental health
This trial tests a digital tool designed to help young people recognize early signs of mental health conditions and take steps toward getting help. It may be a good fit if you are between 12 and 29, live near certain research sites, and can complete a short screening questionnaire in English.
New York, New YorkAges 12–29 - NCT06774430Recruiting
Digital outreach for young people at risk of psychosis
This study tests a digital program designed to encourage young people to seek help for early signs of psychosis. It aims to see if online messages can increase connections to care.
New York, New YorkAges 12–29 - NCT06947941RecruitingPhase 3
Testing karxt for psychosis in alzheimer's disease
This study tests whether a new medicine called KarXT can help with psychosis (hallucinations or delusions) in people with Alzheimer's disease. It aims to reduce troubling symptoms while being safe for older adults.
Gilbert, ArizonaAges 55–90 - NCT06978803Recruiting
Speech and brain study for early psychosis
This study looks at how people with early psychosis (within the first 5 years of treatment) talk during conversations. Researchers hope to learn more about speech patterns and brain activity related to psychosis.
Montreal, QuebecAges 18–60 - NCT07001878RecruitingPhase 4
Cannabis Strength and Brain Health in Early Psychosis
This trial studies how different strengths of cannabis affect the brain's white matter in people with early psychosis. It may help doctors understand which cannabis potencies are less harmful for young adults with psychosis.
St. John's, Newfoundland and LabradorAges 18–25 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT07060742Recruiting
Exergames for older adults with psychosis
This trial tests if playing specially designed video games (called exergames) can help older adults with psychosis improve their physical and mental health. It may be a good fit if you're 55 or older, have a psychotic disorder, and can stand for a few minutes.
Basel, Canton of Basel-CityAges 55 years+ - NCT07093671Recruiting
Therapy for Teens and Young Adults at Risk for Psychosis
This trial tests a type of therapy called Mentalization Based Treatment (MBT) for young people who are at high risk for developing psychosis. The therapy helps you understand your own and others' thoughts and feelings, with the goal of reducing distress and preventing psychosis.
LausanneAges 14–30 - NCT06194799Enrolling by invitationPhase 3
Long-term ACP-204 for Alzheimer's psychosis
This study tests a long-term medicine (ACP-204) for people with Alzheimer's disease who also have psychosis (hallucinations or delusions). If you took part in the earlier ACP-204 study, this open-label extension lets you continue receiving the medicine to see how well it works over time.
Costa Mesa, CaliforniaAges 55–95 - NCT07360665Recruiting
Exercise program for people with psychosis on injectable meds
This trial tests a personalized exercise program for people with psychosis who take long-acting injectable antipsychotics. The goal is to see if regular physical activity can improve overall health and well-being.
Vila RealAges 18 years+ - NCT04007510Enrolling by invitation
Early psychosis study for patients, families, and care teams
This study looks at how to improve early psychosis care using data-driven planning and support for people who are newly developing symptoms. It may help by sharing better ways to coordinate treatment among patients, families, and the clinic/community teams.
Sacramento, CaliforniaAges 8–40 - NCT07450027Recruiting
Blood markers in methamphetamine psychosis
This study looks at two blood proteins (LRFN5 and OLFM4) in people with methamphetamine use disorder or methamphetamine-induced psychosis, compared to healthy controls. Results may help understand the biology of these conditions.
Elâzığ, ElâzığAges 18–49 - NCT06978881Enrolling by invitation
Brain activity study for stable schizophrenia
This study uses a brain scan called magnetoencephalography (MEG) to understand brain activity in people with schizophrenia. It may help researchers learn more about the condition and could lead to better treatments.
Montreal, QuebecAges 18–50 - NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT04323566Enrolling by invitationPhase 2
Rituximab for OCD or psychosis linked to immune inflammation
This trial tests rituximab (an immune system medicine) to see if it can reduce OCD symptoms and/or psychosis when there are signs the immune system may be involved. You may be considered if other standard psychiatric treatments have not helped enough and your illness seems relatively recent with possible inflammation clues.
UppsalaAges 18–55 - NCT04940663RecruitingTeam says not enrolling
Study brain and feelings in loneliness and social isolation
This study looks at how the brain and behavior relate to loneliness and feeling socially isolated in people with serious mental health conditions. It may help researchers understand what drives loneliness and how it could be addressed in the future.
Charlestown, MassachusettsAges 18–55 - NCT05398120Recruiting
Skills group for teens at high risk for psychosis
This study offers a skills-based group program for teens who are considered at high risk of developing a psychotic disorder. It aims to help young people cope and possibly lower the impact of early warning symptoms.
Pittsburgh, PennsylvaniaAges 13–18 - NCT06597864Recruiting
A pilot study of 7-step therapy for self-disorder in early psychosis
This trial tests a new type of talk therapy that helps people with early psychosis explore unusual experiences with their sense of self. It might be a good fit if you've been diagnosed with a psychotic disorder within the last 3 years or have psychosis risk syndrome, and you're motivated to work on these experiences.
Sandvika, BærumAges 18–39 - NCT05728138Recruiting
Talk therapy trial for suicidal thoughts in early psychosis
This study tests a psychosocial (talk-based) intervention for people with early psychosis who are having thoughts about death or being better off dead. It aims to see if the approach is safe and workable, and whether it can help reduce suicidal thinking.
Karachi, SindhAges 18 years+ - NCT04005378RecruitingPhase 4
Finding needs of people in a cancer survivorship program
This study looks at how supported people are and what challenges they may face while enrolled in a cancer survivorship (CSC) program. It aims to identify people at higher risk and improve the services they receive.
Lauderdale Lakes, FloridaAges 15–40
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Common questions
- Are there clinical trials for psychosis?
- Yes. Clin2 currently lists 145 recruiting psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.