Clinical trials
Pulmonary Disease, Chronic Obstructive clinical trials
Below are recruiting pulmonary disease, chronic obstructive clinical trials, each written for real people, not researchers. We’re tracking 345 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05704881Recruiting
Using breath CO2 levels to judge COPD flare severity in ER
This study measures an easy breathing signal called end-tidal carbon dioxide (a CO2 reading from your exhaled breath) to help judge how severe a COPD flare is. It may help doctors decide how closely you need monitoring and treatment during emergency care.
Grenoble, IsèreAges 18 years+ - NCT05717192Recruiting
Bronchoscopy treatment to shrink severe emphysema using heat
This trial studies a bronchoscopy procedure that uses heat (thermoablation) to reduce over-inflated lung tissue in people with severe emphysema. If you qualify, it aims to improve breathing and walking ability after trying standard treatments first.
BerlinAges 40–75 - NCT05730088Recruiting
Helping COPD patients avoid hospital visits with home nursing support
This trial tests whether adding several nursing check-ins and coaching (using home oxygen and regular contact) can help people with severe COPD avoid going back to the hospital. It uses phone or internet tools to support care at home.
KonyaAges 18 years+ - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05772013RecruitingPhase 4
Checking azithromycin prevention for COPD flare-ups
This Phase 4 study looks at optimizing how people with COPD take azithromycin to reduce flare-ups (exacerbations). If you already take azithromycin regularly, the trial may test ways to improve how it’s used safely.
CambridgeAges 40 years+ - NCT05785026Recruiting
Menthol to reduce breathlessness in COPD and healthy adults
This trial tests whether menthol helps with breathlessness (dyspnea) during exercise. You may be asked to do breathing and exercise tests, and to use menthol under study supervision to see if symptoms improve.
LeuvenAges 18 years+ - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05878769RecruitingPhase 3
Long-term safety study for Astegolimab in COPD
This study looks at how safe Astegolimab stays over the long run for people with COPD. It enrolls participants who finished a prior 52-week Astegolimab treatment study and may help confirm long-term side effects and overall safety.
Birmingham, AlabamaAges 40–90 - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05896800Recruiting
Inhaled nitric oxide for moderate to severe COPD symptoms
This study tests whether inhaled nitric oxide gas can improve outcomes in people with moderate-to-severe chronic obstructive pulmonary disease (COPD). It may help reduce breathing problems by targeting how airways and blood vessels respond in the lungs.
Nanjing, JiangsuAges 40–75 - NCT05934565Recruiting
Using mindfulness coaching to help people move more
This trial studies a program that uses mindfulness coaching to help people with chronic lung disease (COPD) and/or heart failure (HF) be more physically active. You may benefit if you can safely start exercising and track your steps using a Fitbit.
Boston, MassachusettsAges 40 years+ - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT05939999Recruiting
Elastic tape plus rehab for COPD breathing problems
This trial studies whether using elastic tape during pulmonary rehabilitation can improve breathing and physical function in people with moderate to very severe COPD. It may help you tolerate rehab exercises more comfortably if you meet their specific health and safety requirements.
São Paulo, São PauloAges Any age - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT06046547Recruiting
Palliative care learning for lung rehab patients
This trial tests adding palliative care education to pulmonary rehabilitation for people with COPD or ILD and their caregivers. It aims to see if this helps improve symptom management and quality of life.
AveiroAges 18 years+ - NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT06068647Recruiting
Ultrasound and breathing tests for lung disease patients
This study uses ultrasound and sensors to monitor lung health in people with certain lung conditions, including those that cause scarring or breathing problems. It aims to find better ways to track lung disease, which could help manage your condition more effectively.
RomeAges 18 years+ - NCT06072690Recruiting
COPD and Heart Health Study
This study looks at how COPD affects your breathing and heart health. It is for people who are newly diagnosed with COPD and have a history of smoking.
Kaunas, Kaunas CountyAges 40 years+ - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85 - NCT06163131Recruiting
How endobronchial valves affect diaphragm movement in emphysema
This trial measures how well your diaphragm (the main breathing muscle) moves after you get endobronchial valves (tiny one-way valves in your airways) for emphysema. It helps doctors see if the valves improve your breathing muscle function.
AarhusAges 18 years+ - NCT06188065Recruiting
Eosinopenia and Recovery in Severe COPD Exacerbation
This study is looking at people admitted to the hospital for a severe COPD flare-up. It checks if a low level of eosinophils (a type of white blood cell) in the blood is linked to how quickly you recover from the flare-up.
North ShieldsAges 35 years+ - NCT06201403Recruiting
COPD: Breathing Muscle Strength and Flexibility Study
This study looks at the strength and flexibility of muscles you use to breathe, including muscles in your chest and neck. If you have moderate-to-severe COPD and have been stable on your medications, it may help researchers understand how these muscles are affected.
Istanbul, ZeytinburnuAges 18–75
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Common questions
- Are there clinical trials for pulmonary disease, chronic obstructive?
- Yes. Clin2 currently lists 345 recruiting pulmonary disease, chronic obstructive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary disease, chronic obstructive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary disease, chronic obstructive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.