Clinical trials
Pulmonary Hypertension clinical trials
Below are recruiting pulmonary hypertension clinical trials, each written for real people, not researchers. We’re tracking 248 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06850792Recruiting
Improving treatment adherence with telemedicine and guidance
This study tests whether regular remote check-ins and guidance can help people with pulmonary arterial hypertension stick to their treatment plan. You would be followed by phone or video from University of Sao Paulo.
São Paulo, São PauloAges 18 years+ - NCT06751082Recruiting
Sotatercept for pulmonary hypertension study
This study looks at how well the drug Sotatercept works for people with pulmonary hypertension (high blood pressure in the lungs) in a real-world clinic setting. If you are already taking Sotatercept, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06658522RecruitingPhase 4
Sotatercept for right heart function in pulmonary hypertension
This study tests a medicine called sotatercept to see if it can improve how the right side of your heart pumps in people with PAH. It may help you feel better and slow down the disease.
Amsterdam, North HollandAges 18–70 - NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06528418Recruiting
Breath test to find lung diseases
This study uses a simple breath test to detect different lung diseases. By analyzing the chemicals in your breath, researchers hope to find a faster, non-invasive way to diagnose lung conditions. It may be an option if you have a known lung disease and have a recent CT scan.
Guangzhou, GuangdongAges 18–100 - NCT06409624Recruiting
Biomarkers and kidney decline in pulmonary hypertension
This study looks at how certain blood markers (biomarkers) relate to kidney function decline in people with pulmonary hypertension. Participants will have blood and urine tests, and their kidney function will be tracked over time.
Bad Nauheim, HesseAges 18 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Birmingham, AlabamaAges 18 years+ - NCT06362382Recruiting
Home rehab via smartphone for pulmonary hypertension
This study tests whether a home-based exercise program, guided by a smartphone app, can improve your daily life and heart function if you have pulmonary hypertension. You will use a wearable device to track your activity and receive remote support from a medical team.
Beijing, Beijing MunicipalityAges 18–60 - NCT07653958Recruiting
Risk factors for sudden high blood pressure in the lungs
This study looks at what might cause a sudden, dangerous rise in blood pressure in the lungs (pulmonary hypertension crisis). Knowing the risk factors could help doctors prevent these episodes.
Guangzhou, GuangdongAges Any age - NCT06336798RecruitingPhase 2
Pioglitazone for pulmonary hypertension from lung disease
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Atlanta, GeorgiaAges 18 years+ - NCT07662655RecruitingEarly Phase 1
PADN for pulmonary hypertension after mitral valve repair
This study tests a new procedure called pulmonary artery denervation (PADN) to lower high blood pressure in the lungs that persists after a mitral valve repair. It aims to see if this extra treatment improves symptoms and outcomes for people with this condition.
Xiamen, FujianAges 18–80 - NCT06135909Recruiting
CHASE registry for pulmonary hypertension patients on treatment
This study is a registry that collects information on people with pulmonary hypertension who are using or starting targeted medications. The goal is to understand how these treatments work in real-world settings and improve care for patients like you.
BeijingAges 18–85 - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT06104228RecruitingPhase 2
Xenon MRI to detect and track pulmonary hypertension
This trial uses a special MRI scan (using xenon gas) to see how well the lungs are working in people with pulmonary arterial hypertension (PAH). It aims to improve diagnosis and monitoring of PAH from connective tissue disease or unknown cause.
Durham, North CarolinaAges 18–75 - NCT05958901Recruiting
Study of pulmonary hypertension in everyday clinical care
This observational study is looking at people diagnosed with pulmonary hypertension to better understand how it behaves over time. You may help researchers by allowing repeated check-ins for years and sharing symptom and test information.
Guangzhou, GuangdongAges 20–70 - NCT05935605Recruiting
Study pulmonary hypertension in heart failure and valve disease
This study looks at pulmonary hypertension—high blood pressure in the lung arteries—in people with certain heart conditions (heart failure with preserved or reduced pumping function, or significant valve disease). It may help doctors better understand how lung blood pressure changes in these heart problems and guide care.
Rochester, MinnesotaAges 18 years+ - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT05566002Recruiting
AI review of test results for pulmonary hypertension
This trial uses an artificial intelligence tool to look at results from tests used to evaluate pulmonary hypertension. It may help doctors make sense of your past test results, especially heart and lung evaluation results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05329714Recruiting
Deep testing registry for people with pulmonary hypertension
This trial is a global registry that collects detailed health information (“deep phenotyping”) from people diagnosed with pulmonary hypertension. It helps researchers better understand the condition and how people differ, which can guide better future treatments.
Giessen, HesseAges Any age - NCT05311072Recruiting
Update a CTEPH patient database in China
This study helps doctors update and improve how they understand chronic thromboembolic pulmonary hypertension (CTEPH) in patients in China. It likely involves sharing your medical information (not a new drug) and confirming your diagnosis details to support future research.
BeijingAges 14 years+ - NCT04991454RecruitingPhase 2
Xenon mri to image lung blood flow in pulmonary hypertension
This trial uses a special MRI scan with xenon gas to take detailed images of how blood moves through your lungs. It aims to see if this imaging can help doctors better understand and manage pulmonary hypertension, which is high blood pressure in the lungs.
Durham, North CarolinaAges 18–75 - NCT04808596Recruiting
Pulmonary hypertension registry and blood sample study
This study builds a registry and collection system for people with pulmonary hypertension, confirmed by a specific heart test. By joining, you help researchers learn more about the condition and may support future studies.
Kansas City, KansasAges 18 years+ - NCT04654650Recruiting
Study of adults with pulmonary hypertension for long-term data
This study follows adults with pulmonary hypertension over the long term and collects information (and possibly samples) to better understand how the condition changes over time. It may help researchers learn what factors affect outcomes, which can improve care in the future.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+
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Common questions
- Are there clinical trials for pulmonary hypertension?
- Yes. Clin2 currently lists 248 recruiting pulmonary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.