Clinical trials
Pulmonary Hypertension clinical trials
Below are recruiting pulmonary hypertension clinical trials, each written for real people, not researchers. We’re tracking 247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06104228RecruitingPhase 2
Xenon MRI to detect and track pulmonary hypertension
This trial uses a special MRI scan (using xenon gas) to see how well the lungs are working in people with pulmonary arterial hypertension (PAH). It aims to improve diagnosis and monitoring of PAH from connective tissue disease or unknown cause.
Durham, North CarolinaAges 18–75 - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Phoenix, ArizonaAges birth+ - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT05935605Recruiting
Study pulmonary hypertension in heart failure and valve disease
This study looks at pulmonary hypertension—high blood pressure in the lung arteries—in people with certain heart conditions (heart failure with preserved or reduced pumping function, or significant valve disease). It may help doctors better understand how lung blood pressure changes in these heart problems and guide care.
Rochester, MinnesotaAges 18 years+ - NCT05844462RecruitingPhase 3
Tadalafil for severe lung blood-pressure problems from COPD
This study tests whether tadalafil can improve outcomes for people with severe pulmonary hypertension caused by COPD (chronic lung disease). It compares how you do with tadalafil versus standard care, focusing on breathing symptoms and how well your heart and lungs cope.
Le Kremlin-Bicêtre, FranceAges 18–85 - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT05462574Recruiting
MRI study of heart fat in pulmonary arterial hypertension
This trial uses MRI (and an additional MRI measurement called MRS) to study fat in the right side of the heart in people with pulmonary arterial hypertension (PAH). It may help researchers understand what’s going on in PAH and how it relates to symptoms and exercise ability.
Nashville, TennesseeAges 18 years+ - NCT04991454RecruitingPhase 2
Xenon mri to image lung blood flow in pulmonary hypertension
This trial uses a special MRI scan with xenon gas to take detailed images of how blood moves through your lungs. It aims to see if this imaging can help doctors better understand and manage pulmonary hypertension, which is high blood pressure in the lungs.
Durham, North CarolinaAges 18–75 - NCT01607502Recruiting
Database study for people with pulmonary hypertension symptoms
This study builds a medical and symptom database for people who have pulmonary hypertension or may be at risk, to better understand the condition. If you choose to participate, your basic health information and symptom history may be recorded and used for research.
GrazAges 18 years+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Phoenix, ArizonaAges 18 years+ - NCT03388476Enrolling by invitation
Breathing carbon dioxide measurement to detect lung high blood pressure
This trial tests whether measuring carbon dioxide you breathe out can help detect pulmonary hypertension earlier. It may help doctors spot this lung blood vessel condition sooner, especially around the time you get a heart test.
Giessen, HesseAges 18 years+ - NCT01730092Recruiting
Study of blood and imaging biomarkers in pulmonary artery hypertension
This study tracks natural changes in “biomarkers” (measurable signals in blood) and imaging findings in people with pulmonary arterial hypertension (PAH) or suspected PAH. It also includes healthy people for comparison, helping researchers understand what these signals mean over time.
Bethesda, MarylandAges 18–100 - NCT01884051Recruiting
Study of blood and skin changes in pulmonary hypertension
This study looks at how hormones, metabolism, and body signals relate to pulmonary arterial hypertension. You may be eligible if you (or a family member) have idiopathic, inherited, or related pulmonary arterial hypertension, and you can do required blood and other testing.
Nashville, TennesseeAges Up to 90 years - NCT01725763Enrolling by invitation
MRI without contrast to help diagnose pulmonary hypertension
This study uses an MRI scan that does not use contrast dye to better diagnose and sort out pulmonary hypertension (high blood pressure in the lungs). It may help doctors classify your condition more accurately, especially around the time you’re scheduled for a right-heart catheterization.
Graz, StyriaAges 18 years+ - NCT01571700Enrolling by invitation
Study breathing-heart timing differences in pulmonary hypertension
This study looks at timing mismatches (“dysynchrony”) in the heart and lungs in people with pulmonary hypertension. It may help researchers understand what causes symptoms and how the timing affects heart function.
Stanford, CaliforniaAges 5 years+ - NCT03959748Recruiting
Pulmonary hypertension patients’ heart-lung pressure database study
This study builds a database of people with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. It may help doctors better understand these conditions in the Polish population and improve future care decisions.
KrakowAges 3 months+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT07850908Enrolling by invitation
Ventilation method for newborns with persistent pulmonary hypertension
This study tests a specific type of breathing machine (ventilator) that adjusts air pressure to help newborns with persistent pulmonary hypertension breathe better. It aims to see if this method improves oxygen levels and outcomes for babies needing mechanical ventilation in their first week of life.
Tanta, Gharbia GovernorateAges 1 day–2 months - NCT06429579Recruiting
Potts shunt for severe pulmonary hypertension in children
This trial tests a surgery called a Potts shunt for children with severe pulmonary hypertension (high blood pressure in the lungs). It may help children who are still very sick despite standard medications.
Beijing, Beijing MunicipalityAges 6 months–18 years - NCT07837830RecruitingEarly Phase 1
Early treatment for exercise-related lung pressure
This trial tests an inhaled medicine that may help people with lung scarring or connective tissue disease who have high blood pressure in the lungs only during exercise. It aims to improve their ability to be active and reduce symptoms.
Paramus, New JerseyAges 18 years+ - NCT06443580Recruiting
A mind-body program for pulmonary hypertension
This trial tests a program that helps you notice and manage body signals (like breathlessness) to improve how you feel day-to-day. It is designed for people with any type of pulmonary hypertension.
Glasgow, ClydebankAges 18 years+ - NCT06386185Recruiting
Using heart tests to better detect pulmonary hypertension
This trial uses data from standard heart tests to develop a better way to detect pulmonary hypertension, a condition of high blood pressure in the lungs. It aims to help doctors diagnose this condition earlier and more accurately.
Bath, BanesAges 18 years+ - NCT06846554RecruitingPhase 2
Study of APL-9796 for Pulmonary Hypertension with CardioMEMS Monitor
This trial tests a study drug called APL-9796 for people with pulmonary hypertension (PH). It may help by using your CardioMEMS monitor to see how well the drug works. You can take part only if you have a CardioMEMS implant and your PH is not too mild or too severe.
London, LondonAges 18–80
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Common questions
- Are there clinical trials for pulmonary hypertension?
- Yes. Clin2 currently lists 247 recruiting pulmonary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.