Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05444270Recruiting
Radiation and medicine for recurrent ovarian cancer
This trial studies a “salvage” (next-line) cancer treatment for recurrent epithelial ovarian cancer, with or without a focused type of radiation. It may help by shrinking or controlling limited spots of cancer that have come back after prior standard treatment.
SeoulAges 19 years+ - NCT05794035Recruiting
Shorter radiation after skin cancer surgery for older adults
This study looks at whether giving a shorter course of radiation after surgery can help prevent skin cancer from coming back in people age 70 and older. It focuses on higher-risk skin cancers and checks how well the treatment works and what side effects occur.
CréteilAges 70 years+ - NCT05258448Recruiting
Chemo-radiotherapy for advanced, non-surgical lung cancer
This trial studies treatment that combines chemotherapy and radiation for people with advanced lung cancer that cannot be removed with surgery. It may help improve cure chances for patients who can complete the study tests, including heart scans.
Odense CAges 18 years+ - NCT05316922RecruitingPhase 3
Lowering thyroid hormone during radiation to prevent low thyroid
This study tests whether using treatment to keep thyroid-stimulating signals low during radiation to the thyroid area can help prevent a treatment-related drop in thyroid function in children. It is aimed at kids with certain cancers whose radiation plan includes thyroid tissue.
MilanAges Any age - NCT06173986RecruitingPhase 1/Phase 2
Immunotherapy plus chemoradiation for advanced esophageal cancer
This trial tests whether adding immunotherapy to standard chemoradiation can help people with unresectable locally advanced esophageal cancer. It aims to improve outcomes for those who cannot have surgery.
ShanghaiAges 18–75 - NCT04894370RecruitingPhase 2
Trial tests immunotherapy plus chemotherapy and radiation for anal cancer
This Phase 2 trial studies a combination of immunotherapy (spartalizumab), chemotherapy (mDCF includes docetaxel), and radiation to treat metastatic or returning anal squamous cell cancer. It may help shrink tumors and improve outcomes compared with standard approaches, but eligibility is strict to keep participants safe.
BesançonAges 18 years+ - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT04831983Recruiting
Radiation treatment for intermediate- and high-risk prostate cancer
This trial studies a type of focused radiation (“ablative radiotherapy”) for prostate tumors considered intermediate- or high-risk. It may help improve control of the cancer while aiming for acceptable side effects.
Monza, MBAges 18–90 - NCT06240689RecruitingPhase 2
Immune maintenance therapy after chemoradiotherapy for head and neck cancer
This trial tests whether adding an immune checkpoint inhibitor (a drug that helps your immune system fight cancer) as maintenance therapy after chemoradiotherapy improves outcomes for people with locally advanced head and neck cancer. It specifically looks at a marker in your blood (CD8Tex cells) to see if you might benefit.
Hangzhou, ZhejiangAges 18–75 - NCT03744819Recruiting
Blood and tissue tests to predict how tumors respond to radiation
This study looks at tumor tissue and/or blood “biomarkers” to help predict whether a solid tumor will respond well to radiation therapy. It may help doctors choose more effective treatments in the future, and it may guide your care during radiotherapy if you qualify.
Shantou, GuangdongAges Any age - NCT05515315RecruitingPhase 2
Immunotherapy plus chemo then chemoradiation for esophageal cancer
This Phase 2 study tests whether adding tislelizumab (an immunotherapy drug) to chemotherapy before a combined course of chemotherapy and radiation can better treat locally advanced, non-surgable esophageal squamous cell cancer. It’s for adults who cannot have surgery and may help shrink the cancer and improve control of the disease.
Fuzhou, FujianAges 18–70 - NCT06185062Recruiting
Pelvic cancer registry for online adapted radiotherapy
This study collects data from patients receiving a type of radiation therapy that is adjusted in real-time. It aims to learn more about how well this approach works for pelvic and chest tumors.
GöttingenAges 18 years+ - NCT07173387RecruitingPhase 2
Radiation plus chemo for locally advanced pancreatic cancer
This trial combines focused radiation with a chemotherapy drug combo to help shrink or control locally advanced pancreatic cancer. If it works, this treatment might make the tumor smaller and improve quality of life.
Jinan, ShandongAges 18–75 - NCT07871838Recruiting
Shorter radiation course for endometrial cancer
This trial tests a shorter course of pelvic radiation for people with endometrial cancer after surgery. It aims to see if it is safe, works well, and improves quality of life.
Montreal, QuebecAges 18 years+ - NCT07865780Enrolling by invitationPhase 1/Phase 2
Laser light with or without oxygen gel for mouth sores from radiation
This study tests two ways to treat painful mouth sores caused by radiation therapy for head and neck cancer. Half of the participants will receive laser light therapy alone, and the other half will receive laser light plus an oxygen gel applied to the sores. The goal is to see if adding the oxygen gel helps the sores heal faster and reduces pain.
AsyutAges 18 years+ - NCT04642027RecruitingPhase 3
PSMA scan-guided salvage radiation after prostate surgery
This trial tests whether using a specialized PSMA PET scan to guide radiation can better treat prostate cancer that returns after prostate surgery. It targets the “prostate bed” area with a shorter, stronger radiation schedule (hypofractionated) to control rising PSA levels.
Arnhem, GelderlandAges 18–80 - NCT06271421Recruiting
Nanoparticle heat therapy for recurrent glioblastoma
This trial tests a new treatment for recurrent glioblastoma using tiny magnetic particles (nanoparticles) that are heated to kill cancer cells. The particles are injected into the tumor, and then a magnetic field device heats them up. It's for people who have already tried standard therapy and whose tumor has come back.
PoznanAges 18 years+ - NCT02454790Recruiting
Follow-up program for people with esophageal cancer
This trial tests a standard follow-up plan for people who have esophageal cancer and received a certain amount of radiation. It may help your care team monitor side effects and catch health changes early.
GroningenAges 18 years+ - NCT07858630Recruiting
Radiation targeting for advanced esophageal cancer with immunotherapy
This trial studies how to best target radiation for people with advanced esophageal cancer who are also getting immunotherapy. It aims to improve treatment planning to help patients live longer with fewer side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT07868861RecruitingPhase 1
Nasal ondansetron versus IV injection in healthy adults
This trial tests a new nasal spray form of ondansetron (a medicine that prevents nausea and vomiting) to see how well the body absorbs it compared with the IV (into the vein) form. It is for healthy adults to help understand how the nasal spray works.
JerusalemAges 18–65 - NCT06297512RecruitingPhase 2
Testing chemotherapy after radiation for young patients with glioblastoma
This trial tests whether a type of chemotherapy called anthracycline can help young patients with glioblastoma when given after radiation therapy. It aims to see if this treatment improves outcomes for patients aged 3 to 30.
FlorenceAges 3–30 - NCT05346367Recruiting
Targeted brain radiation to improve treatment benefit and limit side effects
This study tests a more targeted form of stereotactic (precise) brain radiation for people with brain metastases from large cell cancer. It aims to improve the balance between effectiveness and side effects by carefully focusing where the radiation goes.
Leidschendam, South HollandAges 18 years+ - NCT06187597RecruitingPhase 2
Toripalimab after chemoradiation for older esophageal cancer
This study tests whether adding a drug called toripalimab after standard chemoradiation can help older adults with esophageal cancer. The goal is to see if this treatment can keep the cancer from coming back after initial therapy.
Guangzhou, GuangdongAges 70–85 - NCT06261125RecruitingPhase 2
SBRT plus immunotherapy and targeted drug for liver cancer
This trial tests a combination of radiation (SBRT), an immunotherapy drug (PD-L1 inhibitor), and a targeted therapy (lenvatinib) for people with liver cancer that has spread to abdominal lymph nodes. It may be an option if you haven't taken certain immunotherapies before or if your cancer progressed after them.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,308 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.