Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,307 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07113275RecruitingPhase 3
Short versus long radiation schedule for advanced rectal cancer
This study compares two different schedules of radiation (a short course versus a longer course) followed by standard chemotherapy and immunotherapy for advanced rectal cancer. It aims to see which approach works best to shrink the tumor before surgery.
Wuhan, HubeiAges 18–75 - NCT06311981RecruitingPhase 2
Carbon ion radiation for elderly lung cancer patients
This trial tests carbon ion radiotherapy for adults 75 and older with locally advanced non-small cell lung cancer who cannot have surgery. The goal is to see if this precise type of radiation can treat the cancer effectively with fewer side effects.
Shanghai, Shanghai MunicipalityAges 75 years+ - NCT05224934Recruiting
Radiation before surgery for retroperitoneal soft-tissue sarcoma
This trial tests giving a shorter, lower-dose radiation treatment before surgery for a retroperitoneal (deep belly/back space) soft-tissue sarcoma. The goal is to shrink or control the tumor and make surgery more effective and safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04901234RecruitingPhase 2
Adaptive radiation for advanced throat cancer
This study tests an approach called “adaptive radiotherapy,” where the radiation plan may be adjusted based on how your tumor and anatomy look during treatment. It is for adults with biopsy-proven oropharyngeal (throat) squamous cell carcinoma who are planning curative radiation, with or without chemotherapy.
MelbourneAges 18 years+ - NCT04453826RecruitingPhase 3
Test PD-1 plus chemo-radiation for high-risk nasopharyngeal cancer
This Phase 3 trial tests whether adding a PD-1 immunotherapy (given with chemotherapy and radiation, and also after) can improve outcomes for people with high-risk nasopharyngeal cancer. It may help by strengthening the immune system’s attack on the cancer alongside standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT04453813RecruitingPhase 3
Immunotherapy with chemoradiation for recurring nasopharyngeal cancer
This phase 3 trial tests whether adding toripalimab (an immunotherapy medicine) to standard chemo-radiation works better for treating nasopharyngeal cancer that has come back and cannot be removed by surgery. It aims to improve control of the cancer after it returns.
Guangzhou, GuangdongAges 18–70 - NCT06230549Recruiting
Adaptive radiotherapy for gynecological tumors
This trial tests a personalized radiation therapy approach for gynecological tumors. It aims to improve treatment by adapting the radiation plan based on changes in the tumor and nearby organs during your therapy course.
Essen, Germany / NRWAges 18 years+ - NCT06313450Recruiting
Lower radiation for nose cancer after immunotherapy and chemo
This trial tests whether giving a lower dose of radiation to the main tumor is safe and effective for people with nasopharyngeal cancer (a type of nose/throat cancer) who first receive a combination of immunotherapy (toripalimab) and chemotherapy. It aims to reduce side effects while still controlling the cancer.
Guangzhou, GuangdongAges 18–70 - NCT06345287RecruitingPhase 2
Adaptive radiotherapy after immunotherapy for head and neck cancer
This trial tests a personalized radiotherapy approach after a few rounds of chemo-immunotherapy for people with HPV-negative head and neck cancer. It aims to adjust the radiation dose based on how the tumor responds, possibly reducing side effects while still controlling the cancer.
BeijingAges 18–75 - NCT06216171Recruiting
Adaptive radiation therapy for head and neck cancer
This trial tests a new type of radiation therapy that adjusts during treatment for head and neck tumors. It’s for people who haven’t had cancer treatment before and are otherwise in good health.
EssenAges 18 years+ - NCT07684508Recruiting
Shorter radiation therapy after surgery for cervical cancer
This trial tests a shorter course of radiation therapy (fewer sessions) after hysterectomy for cervical cancer. It aims to see if it's safe and effective for patients who meet certain criteria based on their tumor type and recovery.
Beijing, Beijing MunicipalityAges 18–75 - NCT07674732RecruitingPhase 2
Shorter radiation with immunotherapy for rectal cancer
This trial tests a shorter course of radiation followed by a combination of chemotherapy, immunotherapy, and a targeted drug (bevacizumab) for locally advanced rectal cancer that is mismatch repair proficient (pMMR) or microsatellite stable (MSS). The goal is to see if this approach can shrink the tumor enough for surgery while avoiding more extensive radiation.
Guangzhou, GuangdongAges 18–75 - NCT07584161Recruiting
Radiation therapy comparison after cervical or endometrial cancer surgery
This trial compares two types of radiation therapy (a newer technique called MH-ART versus a standard technique called CF-IMRT) given after surgery for cervical or endometrial cancer. The goal is to see which approach works better and causes fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT06826885Recruiting
Comparing two types of radiation for breast cancer
This trial is testing how well two different radiation techniques, IMPT and IMRT, work for treating breast cancer. It aims to see which one is safer and more effective, so you might benefit from a potentially better treatment approach.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06641635RecruitingPhase 3
Shorter radiation schedule with adaptive planning for cervical cancer
This trial tests a shorter, personalized radiation schedule for cervical cancer. It uses daily CT scans to adjust the radiation beam for better targeting. It may mean fewer hospital visits and less damage to healthy tissue.
BeijingAges 18–75 - NCT07230639RecruitingPhase 2
Shorter radiation with chemo and immunotherapy for high-risk colon cancer
This trial tests a shorter course of radiation combined with chemotherapy and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of high-risk colon cancer that has not spread. The goal is to see if this approach can shrink the tumor before surgery and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06928584RecruitingPhase 2
Shorter Radiation Plus Immunotherapy for Recurrent Rectal Cancer
This trial tests whether a shorter, higher-dose radiation course (hypofractionated) combined with immunotherapy works better than standard radiation for locally recurrent rectal cancer that hasn't spread elsewhere. It's for people who haven't had chemotherapy or recent pelvic radiation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06306170Recruiting
Advanced radiation for gynecologic cancer
This trial is for people with gynecologic cancer who will receive modern, targeted radiation therapy. It aims to see how well these advanced treatments work and how patients feel during and after therapy.
Milan, MIAges 18–90 - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT07015892RecruitingPhase 3
Higher radiation dose for limited-stage small cell lung cancer
This trial tests a higher dose of radiation therapy for people with limited-stage small cell lung cancer (cancer that hasn't spread beyond the chest). It aims to see if the higher dose works better than the standard dose at controlling the cancer.
Salamanca, SalamancaAges 18 years+ - NCT06980259Recruiting
Comparing two types of radiation for soft tissue sarcoma
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
Jinan, ShandongAges 18–70 - NCT06546267Recruiting
Advanced radiotherapy for prostate cancer
This trial tests advanced radiotherapy techniques in men with prostate cancer to see how well they work. If you are over 18 and have prostate cancer, this study might be an option for you.
MilanAges 18–95 - NCT06958432RecruitingPhase 2/Phase 3
Shorter radiation before chemo and immunotherapy for rectal cancer
This trial tests a shorter course of radiation before chemotherapy and an immunotherapy drug to shrink mid-to-lower rectal cancer that has not spread. The goal is to improve treatment response and reduce side effects, potentially allowing for less invasive surgery.
Guangzhou, GuangdongAges 18–75 - NCT06186726RecruitingPhase 2
Carbon ion radiation with chemo for thymic cancer
This trial tests a new type of radiation (carbon ion) plus chemotherapy for thymic tumors that cannot be removed with surgery. It aims to see if this combination can effectively treat the cancer while protecting healthy organs.
Shanghai, Shanghai MunicipalityAges 18–70
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,307 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.