Randomized Controlled Trial clinical trials

EMDR therapy for young children with stress and anxiety

This study tests whether EMDR therapy (a structured way to help process distressing experiences) helps children ages 3 to 6 who have symptoms related to trauma, stress, or anxiety. You’d be randomly assigned to receive the study therapy or a comparison condition, and researchers would track outcomes.

Testing a culturally adapted CBT vs. standard CBT

This study tests whether a version of cognitive behavioral therapy (CBT) that is specially adapted for people in Pakistan works better than standard CBT. If you have depression or anxiety, you may be able to join.

Study of aescin plus MPFF for bleeding hemorrhoids

This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.

Using a placebo to help reduce opioid pain medication

This trial tests whether a special placebo pill, given with your knowledge, can help you reduce your opioid pain medication. You'll work with your own doctor to safely lower your dose while taking the placebo.

Therapy program to help parents and teens with scoliosis anxiety

This study tests whether Acceptance and Commitment Therapy (a structured talk-therapy approach) can improve parents’ and teens’ psychological well-being. It compares this therapy to other active support programs for families dealing with adolescent idiopathic scoliosis.

Animation to calm kids before ear tube surgery

This study tests if showing children an educational animation before ear tube surgery can lower their fear and anxiety. It’s a simple, short video that explains what will happen, and the goal is to help your child feel calmer.

Gel for gum treatment after deep cleaning

This trial tests if a special gel placed in the gums after deep cleaning helps treat periodontitis (advanced gum disease). You may qualify if you have gum pockets of 5mm or deeper that bleed when probed.

Lifestyle program for cancer survivors with early heart strain

This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.

Mindfulness program for teens with negative feelings

This study tests a mindfulness program designed to help teenagers manage negative emotions like sadness, worry, or anger. It is for teens who do not already have a diagnosed anxiety or depression disorder, and it takes place online for families in three states.

Muscle vibration during cycling exercise study

This trial tests whether applying gentle vibrations to your leg muscles during cycling can boost power and muscle activity. You will do a series of cycling tests while the vibration is on or off.

Virtual Reality to Reduce Anxiety During Cervical Screening

This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.

Collagen scaffold with gum surgery to improve orthodontic results

This trial tests if a special collagen scaffold placed during gum surgery can improve orthodontic treatment for people with thin gums. It may help protect the gums and bone during teeth straightening.

Nurse coaching to help control high blood pressure

This study tests whether regular phone or video coaching from a nurse helps people with high blood pressure better manage their condition and take their medications. You'll receive personalized guidance to improve your health habits and blood pressure control.

Personalized thinking training for psychosis

This trial tests a personalized thinking training program for people with schizophrenia to help reduce symptoms like delusions or suspiciousness. It might be a good fit if you have had some of these symptoms recently and are stable on your current treatment.

Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment: A Four-Arm Randomized Controlled Trial

The Effects of Light-Targeted Balance Training on Balance, Functional Performance, and Fear of Falling in Individuals With a History of Falls: A Randomized Controlled Trial

Preventing Teacher Violence in Zambian Schools

This study tests a program to prevent teachers from using violence against children in Zambian public primary schools. It aims to see if training and support for teachers reduces violence and improves the school environment.

How fasting time before banding affects bleeding risk

This study looks at whether the length of time you fast before a procedure to treat varices (enlarged veins in the esophagus) affects the chance of bleeding after the procedure. The procedure, called banding, places small rubber bands around the veins to stop or prevent bleeding.

Web-based moral elevation for veterans with PTSD

This trial tests a website designed to help veterans with PTSD feel inspired by stories of others' good deeds, which may reduce PTSD symptoms. You would complete sessions online and answer questions about your experiences.

Comparing sedatives for nausea after gallbladder surgery

This study compares two different sedative medications used during anesthesia to see which one helps prevent nausea and vomiting after gallbladder removal surgery. Participating may help you recover more comfortably after your procedure.

Drain placement in c-section for women with thick belly fat

This trial tests if placing a small drain under the skin during a cesarean section reduces surgical site infections in women with a belly fat thickness of 4 cm or more. It may help prevent infections and improve recovery.

Tricuspid valve replacement using a new catheter device

This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.

Gabor visual training for adult lazy eye

This study tests a home-based visual training program that uses special patterns to help improve vision in adults with amblyopia, often called lazy eye. It may offer a new way to gain visual improvement.

Intrauterine insemination after pregnancy loss

This study tests whether intrauterine insemination (IUI), a simple procedure where sperm is placed directly into the uterus, improves the chance of a successful pregnancy for couples who have had at least one unexplained miscarriage. It aims to help couples who are trying again within a year of their loss.