Clinical trials
Randomized clinical trials
Below are recruiting randomized clinical trials, each written for real people, not researchers. We’re tracking 1,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05439005RecruitingPhase 3
Opioid-free anesthesia for breast reconstructive flap surgery
This trial compares opioid-free anesthesia with opioid-based anesthesia during breast free-flap reconstruction surgery. It aims to see whether avoiding opioids can improve safety and comfort around the time of surgery.
ParisAges 18 years+ - NCT05395949Enrolling by invitation
Treat breast inflammation with support for mental health
This study looks at a non-surgical (“conservative”) approach to treating granulomatous lobular mastitis, along with help for mental health symptoms. It may help people whose breast inflammation and mental health concerns happen together.
Wuhan, HubeiAges 18–60 - NCT05363345Recruiting
Test of two types of baskets to remove bile duct stones
This trial compares two tools used during an endoscopy to remove large stones from the common bile duct (the tube that carries bile from the liver to the gut). It may help find which basket works better and safer for stone removal after a balloon dilation procedure (EPLBD).
Komagane, NaganoAges Any age - NCT05373758Recruiting
Help for people whose HIV treatment is not working
This trial tests different ways to manage “virologic failure,” meaning HIV viral load stays high while taking TLD (a common HIV medicine combination). It may help people better control the virus and improve treatment results, especially in parts of sub-Saharan Africa.
DurbanAges 15 years+ - NCT05411718RecruitingPhase 2
Aspirin or naproxen to prevent cancer in Lynch syndrome
This trial tests whether daily aspirin or naproxen can “intercept” (stop) cancer from starting or coming back in people with Lynch syndrome who are currently cancer-free. Participants are randomly assigned to one of the two drugs, and neither the participant nor the team knows which one you’re taking.
Houston, TexasAges 18 years+ - NCT05361811Recruiting
Therapy coaching for parents of children with rare genetic syndromes
This trial tests an “Acceptance and Commitment Therapy” program for parents or legal guardians who feel moderate parenting stress. It aims to help caregivers cope in healthier ways and may also improve how they manage stress while supporting their child.
Bethesda, MarylandAges 18 years+ - NCT05346848RecruitingPhase 2
Darolutamide plus radiation for intermediate-risk prostate cancer
This trial tests whether adding darolutamide to standard radiation can better control intermediate-risk prostate cancer. It includes men whose cancer has spread nowhere else and who are newly diagnosed with “unfavorable intermediate risk” or progress to that risk group.
AvignonAges 18 years+ - NCT05314998RecruitingPhase 3
Chemo after fully removed pancreatic cancer, guided by gene testing
This Phase 3 study tests whether people with pancreatic cancer should get standard chemo or a chemo plan guided by a tumor gene/RNA test after surgery. It aims to see if the right chemo choice for your tumor biology can improve outcomes after your tumor is removed.
AachenAges 18–79 - NCT05089227RecruitingPhase 2
Long-term apixaban to prevent clots in autoimmune hemolytic anemia
This Phase 2 trial tests whether taking long-term apixaban (a blood thinner) can prevent venous blood clots in people with autoimmune hemolytic anemia (AIHA). It may help reduce the risk of dangerous clotting events if you meet safety and risk criteria.
DijonAges 18 years+ - NCT05208047RecruitingPhase 3
CGT9486 plus sunitinib for advanced gastrointestinal stromal tumors
This trial tests whether adding a new drug called CGT9486 to sunitinib (a standard cancer drug) works better than sunitinib alone for gastrointestinal stromal tumors (GISTs) that have grown or spread. You may qualify if your GIST stopped responding to or caused problems with imatinib, an earlier treatment.
Birmingham, AlabamaAges 18 years+ - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT05230914Recruiting
Choosing the best scan for stroke clot removal
This trial compares different scan choices to help doctors decide the best approach for removing a stroke clot. It aims to improve outcomes after emergency stroke treatment by using the right imaging information.
Wuhu, AnhuiAges 18 years+ - NCT05244486Recruiting
RestoreX traction therapy after prostate surgery
This trial studies whether RestoreX penile traction can help preserve erectile function after a prostatectomy (surgery to remove the prostate), especially when nerves are spared. If you qualify, you may be asked to use the device and be followed over time to see how erections change.
Phoenix, ArizonaAges 18 years+ - NCT05163119Recruiting
Phone-use coaching app for young drivers in Columbus
This study tests a mobile app to help young drivers reduce handheld calling or texting while driving. You may be asked to use the app and follow study steps so researchers can compare outcomes between different groups.
Columbus, OhioAges 18–24 - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05190978Recruiting
Test mesh use for breast reconstruction above the muscle
This study tests whether using surgical mesh can be done safely and works well in breast reconstruction done right away, in front of the chest muscle (pre-pectoral) using tissue expanders. It may help improve how the reconstructed area holds up, but you’d need to meet specific surgical and health requirements.
Los Angeles, CaliforniaAges 22–75 - NCT05171244Recruiting
Virtual reality training for kids with autism
This study tests whether immersive virtual reality (VR) training can improve how children with autism process different sensory information (like sights and sounds). It will compare children who do the VR training with another group as part of a pilot study at a child psychiatry center.
Tours, ToursAges 8–16 - NCT05145491Recruiting
Immediate or delayed surgery for vision changes from ERM
This trial compares doing ERM surgery right away versus waiting at least 4 weeks to see if your vision stays stable. It may help people decide the safest timing for surgery when the membrane in the retina (ERM) is causing symptoms.
Scottsdale, ArizonaAges 50 years+ - NCT05152472RecruitingPhase 2
Imatinib plus atezolizumab versus imatinib alone for advanced GIST
This Phase 2 trial tests whether adding atezolizumab (an immune medicine) to imatinib works better than imatinib by itself in people with advanced gastrointestinal stromal tumors (GIST) that can’t be fully removed and have progressed after standard treatments. It may help by improving how well tumors respond and how long disease stays under control.
Lyon, RhôneAges 18 years+ - NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
Phoenix, ArizonaAges 18 years+ - NCT05109689Enrolling by invitation
ACT-P or T4C support programs after community reentry
This study compares two different programs meant to help people adjust when they return to the community. If you’re considered medium-to-high risk, you may be offered one program at random to see which works better for reducing problems and supporting successful reentry.
Fort Dodge, IowaAges 18 years+ - NCT05085210Recruiting
Brain stimulation to improve parts of lost vision
This study tests whether a noninvasive brain stimulation treatment (tRNS) plus visual training can improve visual field problems after a stroke. It may help some people regain better visual perception in the area they lost.
Boston, MassachusettsAges 18–80 - NCT05064540Recruiting
Testing a new EVAR approach for unruptured AAA
This trial studies an endovascular (through blood vessels) repair technique for an unruptured enlarged artery in the belly called an abdominal aortic aneurysm (AAA). It may help doctors compare outcomes using a randomized approach and structured follow-up.
Huntsville, AlabamaAges 21 years+ - NCT05036590Recruiting
Testing a family support program for first-episode psychosis
This study checks whether a structured family intervention helps caregivers support a person with schizophrenia or a first psychotic episode. You may be asked to take part in a step-by-step program and answer questions to see if it works better than usual care.
BronAges 18 years+
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Common questions
- Are there clinical trials for randomized?
- Yes. Clin2 currently lists 1,177 recruiting randomized studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.