Clinical trials
Reconstructive Surgery clinical trials
Below are recruiting reconstructive surgery clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07431099Recruiting
Skin color matching in head and neck reconstruction
This trial tests a new way to match skin color during reconstructive surgery on the head and neck. It may help improve how the surgical site looks and how you feel about your appearance.
Guilford, ConnecticutAges 18 years+ - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT07335354Recruiting
Decision tool for breast reconstruction after mastectomy
This study is testing a decision tool to help people who are thinking about breast reconstruction surgery after a mastectomy. The tool is designed to help you and your doctor make a more informed choice.
Basking Ridge, New JerseyAges 18 years+ - NCT07084740Recruiting
Study of blood flow in skin flaps for reconstruction
This study looks at how blood flows through special skin flaps used in reconstructive surgery. It may help doctors better understand and predict how these flaps heal, especially for people who need repair after injuries or pressure sores.
MontpellierAges 18–70 - NCT07012642RecruitingEarly Phase 1
GLP-1 drugs for arm or leg swelling (lymphedema)
This trial tests if a class of diabetes drugs (GLP-1 receptor agonists) can reduce swelling in one arm or leg caused by lymphedema. It may help people who have not found relief from other treatments.
Red Bank, New JerseyAges 18 years+ - NCT06798922RecruitingPhase 3
Flap-sparing radiation for mouth cancer after reconstructive surgery
This trial tests a special radiation technique for people who have had reconstructive surgery for oral cavity cancer. The goal is to see if we can spare the flap (the rebuilt tissue) from high radiation doses to improve healing and quality of life.
AmiensAges 18 years+ - NCT06711965Recruiting
Custom molds for breast reconstruction shaping
This trial tests custom 3D-printed molds to help shape breast tissue during reconstruction. It is for people who are already planning a DIEP or TRAM flap after mastectomy.
Houston, TexasAges 18 years+ - NCT05593887Recruiting
Compare three surgeries for late hip dislocation in non-walking children with CP
This trial looks at which surgery works best for children with cerebral palsy who do not walk and have a neglected, deformed hip that has dislocated for a long time. The goal is to compare outcomes after three different hip procedures.
Cairo, AbbasiaAges Any age - NCT06258863Enrolling by invitation
Comparing incision types in breast reconstruction after mastectomy
This study compares different types of surgical cuts (incisions) used during breast reconstruction after mastectomy. It looks at which incision gives the best cosmetic result and causes the fewest problems. Researchers want to find out which technique is best for you.
Wuhan, Hongshan DistrictAges 18 years+ - NCT05439005RecruitingPhase 3
Opioid-free anesthesia for breast reconstructive flap surgery
This trial compares opioid-free anesthesia with opioid-based anesthesia during breast free-flap reconstruction surgery. It aims to see whether avoiding opioids can improve safety and comfort around the time of surgery.
ParisAges 18 years+ - NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT04715139Recruiting
Testing safety of specific foot and ankle implants
This study follows people who get certain Arthrex foot and ankle implants to check how safely they heal and work over time. It may help your care team by adding long-term information about these devices.
Sacramento, CaliforniaAges 2 years+ - NCT04597372RecruitingPhase 2
Tamsulosin for bladder urine retention after pelvic surgery
This trial studies whether tamsulosin can help drain the bladder when urine builds up after pelvic reconstructive surgery. It may help reduce the time and problems caused by “post-operative urinary retention.”
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04003038Recruiting
Negative pressure wound dressings after breast reconstruction in obesity
This trial tests whether a special “suction” dressing (negative pressure wound therapy) helps wounds heal better after breast reconstruction using tissue from the belly, especially in people with higher body weight. You may be more likely to benefit if you’re at higher risk for wound problems after abdominal flap surgery.
Houston, TexasAges 18 years+ - NCT03442465Recruiting
Study of healing and function after bone reconstruction surgery
This study looks at how well people heal and how well they can move and use the repaired bone after reconstructive surgery for bone tumors. It may help doctors understand what recovery looks like and what could improve function over time.
Basking Ridge, New JerseyAges 4 years+ - NCT07059104Recruiting
Breast reconstruction after weight loss surgery study
This study looks at how breast reconstruction with implants works for women who have had major weight loss surgery. It uses national health registries to track outcomes and help doctors and patients make better choices.
GothenburgAges Any age - NCT07602374Recruiting
Written vs. Video Education for Breast Reconstruction Surgery
This study compares two ways of learning about breast reconstruction options after mastectomy—reading written materials versus watching videos. Researchers want to see which method helps patients make better-informed decisions and feel more confident about their choice.
San Francisco, CaliforniaAges 18 years+ - NCT06744387Recruiting
Monitoring oxygen in thigh flaps after reconstructive surgery
This trial tests a device that measures oxygen levels in skin flaps used during reconstructive surgery. It may help doctors ensure the flap is healing well after surgery on an arm or leg.
Edegem, AntwerpAges 18 years+ - NCT07171346Enrolling by invitation
Muscle stimulator after ACL reconstruction
This study tests whether a special muscle-stimulating device worn after ACL reconstruction surgery can help your knee recover strength faster. If you qualify, you will use the device at home for a few weeks and your recovery will be checked regularly.
Kansas City, KansasAges 15–50 - NCT06311058Recruiting
Protein supplement study for ACL surgery recovery
This trial tests whether a protein supplement can help you recover strength and muscle after ACL surgery. You will continue your standard rehab and take a protein drink daily for several weeks.
Houston, TexasAges 16–40 - NCT06080178RecruitingPhase 4
Goal-directed fluids during breast reconstruction surgery
This trial tests a precise fluid management strategy during DIEP flap breast reconstruction to improve outcomes. It aims to reduce complications and improve recovery.
Ghent, East FlandersAges 18–70 - NCT06800547Recruiting
Studying latissimus dorsi flap reconstruction outcomes
This trial looks at patients who had a type of breast reconstruction called a latissimus dorsi flap. It reviews surgery time, hospital stay, and whether any additional operations or cancer recurrences happened. The goal is to learn more about how this procedure works over time.
BolognaAges 18 years+ - NCT07009392Recruiting
Bacteria in the knee during ACL surgery
This study looks for bacteria inside the knee joint during ACL (anterior cruciate ligament) surgery, either for the first time or after a previous surgery. The goal is to learn more about the knee's natural bacteria, which might help improve recovery and prevent infections.
LyonAges 18 years+ - NCT06903468Recruiting
New cavity marking technique for breast cancer surgery and radiation
This trial tests a new way to mark the area where breast cancer is removed during lumpectomy with oncoplastic reconstruction. The goal is to make follow-up radiation more precise and reduce the need for additional surgeries.
Gainesville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for reconstructive surgery?
- Yes. Clin2 currently lists 96 recruiting reconstructive surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a reconstructive surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a reconstructive surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.