Clinical trials
Rectal Cancer Patients clinical trials
Below are recruiting rectal cancer patients clinical trials, each written for real people, not researchers. We’re tracking 360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07339761Recruiting
Sexual health support for bladder cancer patients
This study from the University of Aarhus looks at ways to support sexual health in people who have been treated for bladder cancer. If you are a Danish-speaking adult who had bladder cancer treatment about a year ago and have noticed changes in sexual function, you may be able to join.
AarhusAges 18 years+ - NCT05186116Recruiting
Liver transplant for colon cancer that cannot be removed
This trial studies whether liver transplant (rather than removing the liver tumors) can help some people with colon or rectal cancer spread to the liver. It’s meant for people whose cancer has responded or stayed controlled on standard treatments and who have no cancer outside the liver.
Modena, MOAges 18–77 - NCT04854213Recruiting
Study checks radiation effects in colon cancer lung-limited spread
This trial studies how targeted radiation (SBRT) affects cancer biology and immune cells in people with colon cancer that has spread only to a small number of lung nodules. Your tumor tissue will be analyzed to see what changes after treatment.
Naples, NAPOLIAges 18–80 - NCT07419490Recruiting
Moving ovaries and uterus to preserve fertility during pelvic radiation
This trial moves the ovaries and uterus higher in the belly before pelvic radiation to protect them, so patients may still be able to have children later. It is for women aged 18-40 with pelvic cancers that require radiation.
Tampa, FloridaAges 1.5 years–3.3 years - NCT07407647RecruitingPhase 2
Vaginal DHEA for better vaginal health after pelvic radiation
This study tests whether a vaginal insert of DHEA (a hormone) can help with vaginal health problems caused by pelvic radiation for anal, rectal, or gynecologic cancers. It is for women who are already postmenopausal and are about to start radiation.
Columbus, OhioAges 50 years+ - NCT05793554Recruiting
AI checks cancer type during rectal surgery in real time
This study tests an AI system that helps identify cancer or polyp findings during rectal surgery or assessment, using real-time information. It may help surgeons classify tissue more accurately while you are already getting treatment.
Dublin, IrelandAges 18 years+ - NCT06965335Recruiting
Early-onset colorectal cancer study
This study looks at colorectal cancer that starts early in life (ages 18–40). It compares it to the same cancer in people over 60 to find differences. You can join if you have had colorectal cancer and can provide a sample of your tumor.
Milan, MilanoAges 18–40 - NCT06287814Recruiting
Blood test to detect leftover cancer DNA in colorectal cancer patients
This study uses a simple blood test (liquid biopsy) to look for tiny bits of tumor DNA remaining after colorectal cancer surgery. It aims to see if the test can help predict whether the cancer will come back, especially in people with stage III cancer who will receive chemotherapy.
Montpellier, HéraultAges 18 years+ - NCT06613165Recruiting
Short vs long treatment for stage II-III rectal cancer with dMMR
This trial tests how long you need a PD-1 immunotherapy before surgery for a specific type of rectal cancer (dMMR/MSI-H). It looks at whether a shorter or longer course works best. This could mean fewer side effects and a quicker path to surgery.
Xi'an, ShaanxiAges 18–80 - NCT07003022RecruitingPhase 2
Two-drug combo for advanced colorectal cancer
This trial tests a combination of two drugs (cadonilimab and an anti-angiogenic agent) for advanced colorectal cancer that has a specific genetic feature (dMMR or MSI-H). It aims to find a new treatment option that might work better than current therapies.
Shanghai, ChinaAges 18–80 - NCT07607990Recruiting
Rectal Indomethacin to Prevent Catheter Discomfort After Prostate Surgery
This study tests whether a special suppository (indomethacin, a pain-relieving medication) placed in the rectum can reduce bladder catheter discomfort after laparoscopic prostate removal surgery. If it works, it could help patients recover more comfortably.
Hangzhou, ZhejiangAges 18–80 - NCT06560671Recruiting
App vs. paper for colonoscopy prep education
This study compares a new smartphone app to standard paper instructions for helping patients get their bowel ready for colonoscopy. It aims to see which method is easier to understand and leads to a better exam.
HsinchuAges 18 years+ - NCT04087421RecruitingPhase 3
Transanal irrigation vs glycerol suppositories for LARS
This trial compares two ways to help bowel control in people with low anterior resection syndrome (LARS) after low rectal surgery. It aims to see which option works better when standard treatments have not helped enough.
AarhusAges 18 years+ - NCT07730541Recruiting
Special MRI for rectal cancer before treatment
This trial uses a special MRI technique to help doctors better understand rectal cancer before treatment. It is for people who will receive chemotherapy and radiation before surgery.
TaoyuanAges 20 years+ - NCT07646639RecruitingPhase 2
Radiation, chemotherapy, and immunotherapy for advanced rectal cancer
This study tests a combination of radiation therapy, chemotherapy drugs (capecitabine and oxaliplatin), and two types of immunotherapy (a PD-1 blocker and IL-2) for locally advanced rectal cancer. The goal is to see if this combination helps shrink tumors and improve outcomes before surgery.
Nanjing, JiangsuAges 18–70 - NCT07573371Recruiting
Understanding bowel changes after rectal cancer surgery
This study helps doctors better understand and treat bowel control problems that can happen after rectal cancer surgery or other rectal treatments. If you've had this surgery or treatment, the study team wants to learn more about your recovery and test new ways to help.
AalborgAges 18 years+ - NCT06542588RecruitingPhase 2
Short radiation plus chemo and immunotherapy for rectal cancer
This trial tests a combination of short-course radiation, chemotherapy, and two types of immunotherapy (HLX07 and Serplulimab) before surgery for advanced rectal cancer. It aims to see if this approach helps shrink tumors and improve outcomes.
Wuhan, HubeiAges 18–75 - NCT07537998RecruitingPhase 2/Phase 3
Intestinal Fluid Recycling to Reduce Bowel Problems After Rectal Cancer Surgery
This trial tests a surgical technique that recycles intestinal fluids during rectal cancer surgery to help prevent bowel dysfunction and frequent bowel movements after surgery. If you've had mid-to-low rectal cancer removed and created a temporary opening (stoma), this study may help improve your quality of life.
Guangzhou, GuangdongAges 18–75 - NCT07501845Recruiting
Registry for MAASTRO rectal applicator treatment
This study collects data from people treated with a special rectal applicator for rectal cancer. The goal is to observe long-term outcomes and improve future treatments.
MaastrichtAges 18 years+ - NCT07448077RecruitingPhase 2
Short radiation with immunotherapy for rectal cancer
This trial tests a combination of short-course radiation, chemotherapy, and an immunotherapy drug (Enlonstobart) for patients with a specific type of rectal cancer called pMMR. It aims to see if this approach can shrink tumors before surgery and improve outcomes.
Shijiazhuang, HebeiAges 18 years+ - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06923345RecruitingPhase 2
Modified long-course radiation and chemo with immunotherapy for rectal cancer
This trial tests a treatment plan involving radiation, chemotherapy, and an immunotherapy drug (a PD-1 inhibitor) for people with a specific type of high-risk rectal cancer. The goal is to see if this combination helps shrink the tumor before surgery.
Guangzhou, GuangdongAges 18–75 - NCT07085169RecruitingPhase 2
Low-dose chemo combo for advanced colorectal cancer
This trial tests a lower dose of a chemotherapy pill (trifluridine/tipiracil) combined with bevacizumab for advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if this combination can help control the cancer with fewer side effects.
SanmingAges 60 years+
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Common questions
- Are there clinical trials for rectal cancer patients?
- Yes. Clin2 currently lists 360 recruiting rectal cancer patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rectal cancer patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rectal cancer patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.