Clinical trials
Recurrent or Metastatic Solid Tumors clinical trials
Below are recruiting recurrent or metastatic solid tumors clinical trials, each written for real people, not researchers. We’re tracking 3,299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07710690RecruitingPhase 1
Study of NRG-103 injection for recurrent high-grade glioma
This trial tests a new injection called NRG-103 for people whose high-grade glioma (a fast-growing brain tumor) has come back after standard treatments. The goal is to see if it's safe and if it might help shrink the tumor.
ShanghaiAges 18 years+ - NCT07714863Recruiting
Can machine learning predict ABPA recurrence?
This study uses a computer model to see if it can predict when ABPA (a lung condition) might come back. If you have ABPA and are stable after treatment, this could help doctors monitor you better.
Jinan, ShandongAges 18 years+ - NCT02292641Recruiting
MRI study for repeat pelvic colorectal cancer
This study uses a special MRI to help understand and stage colorectal cancer that has come back in the pelvis. The goal is to improve how doctors make treatment decisions after previous surgery.
OsloAges 16 years+ - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT07703735Enrolling by invitation
Survival after ABO-mismatch living donor liver transplant for liver cancer
This trial looks at how well patients with liver cancer do after receiving a living donor liver transplant that is not the same blood type. It compares survival and cancer return for these patients.
Ages 18 years+ - NCT07698886RecruitingPhase 2
Laser plus Geniwa gel for recurring genital warts
This trial tests whether adding a special gel (Geniwa gel) to standard laser treatment helps prevent genital warts from coming back. It may be an option for people who have already tried laser treatment but their warts returned.
Hanoi, None (International)Ages 18 years+ - NCT07698899RecruitingPhase 1
Study of a new treatment for childhood brain and CNS cancers
This trial tests a radioactive drug (177Lu-DTPA-Omburtamab) given directly into the fluid around the brain for children and teens with certain brain cancers or cancers that have spread to the central nervous system. It aims to see if this treatment is safe and effective for tumors that have come back or not responded to other therapies.
Basking Ridge, New JerseyAges 3–22 - NCT04921527RecruitingPhase 3
Chiauranib with weekly paclitaxel for tough ovarian cancer
This Phase 3 trial tests whether chiauranib combined with weekly paclitaxel can shrink recurrent ovarian, fallopian tube, or primary peritoneal cancer that did not respond to platinum chemotherapy. It is designed for people who have limited treatment options after platinum-resistant or platinum-refractory disease.
Shanghai, ChinaAges 18–70 - NCT06650826Recruiting
Antibodies and blood clots in young adults
This study looks for certain antibodies in the blood of people aged 18 to 60 who have had a blood clot without a clear cause, or soon after an infection or vaccine, or who have had clots return despite treatment. It aims to understand why these clots happen.
BerlinAges 18–60 - NCT06650332RecruitingPhase 1/Phase 2
Cadonilimab combo for first-line HER2-positive gastric cancer
This trial tests a new combination treatment (cadonilimab plus chemotherapy) as the first therapy for people with advanced gastric or gastroesophageal junction cancer that has a certain amount of HER2 protein. It aims to see if this combination can shrink tumors and help people live longer.
Hangzhou, ZhejiangAges 18–75 - NCT07690579Recruiting
Prostate cancer disparities study
This study looks at how social, lifestyle, and other factors affect prostate cancer outcomes. It enrolls men who have chosen to have their prostate removed (radical prostatectomy) and agreed to join a biobank.
San Francisco, CaliforniaAges 18 years+ - NCT07694674Recruiting
Comparing Biologic Drugs to Prevent Crohn's Return After Surgery
This trial compares different biologic medications to see which best prevents Crohn's disease from coming back after intestinal surgery. It may help you if you have had surgery for Crohn's and are starting a biologic drug soon after.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06617481RecruitingPhase 2
PET scan study for early prostate cancer recurrence
This trial uses a special PET scan to detect prostate cancer when your PSA level is slightly rising after prostate removal surgery. It aims to find cancer early so treatment decisions can be better informed.
Orlando, FloridaAges 18 years+ - NCT07683195Enrolling by invitation
Using CT scans to predict early stomach cancer return
This study uses information from CT scans done before stomach cancer surgery to see if it can predict whether the cancer may come back early. Researchers want to find patterns in the scans that might help doctors plan better follow-up care.
Jinan, ShandongAges 18–85 - NCT06251700Recruiting
AI-assisted colonoscopy and long-term polyp prevention
This study checks if using AI during colonoscopy helps prevent growths from coming back. You'd need to have been in an earlier AI-colonoscopy study and be willing to come back for a follow-up colonoscopy 3 years later.
Hong KongAges 18 years+ - NCT07678684RecruitingPhase 2
Study of HF1K16 plus bevacizumab for recurrent glioma
This trial tests a new combination of two drugs, HF1K16 and bevacizumab, for people whose glioma has come back or grown after prior treatment. It aims to see if this combination can help when standard options are no longer working or tolerable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07673367RecruitingPhase 2
Nemtabrutinib with CAR T for relapsed mantle cell lymphoma
This trial tests adding a targeted pill (nemtabrutinib) to standard CAR T-cell therapy for people with mantle cell lymphoma that has come back or not responded to treatment. The goal is to see if this combination works better than CAR T alone.
Nashville, TennesseeAges 18 years+ - NCT07671677Recruiting
BodyGuardian monitoring after AF ablation
This study tests using a portable heart monitor called BodyGuardian to check for atrial fibrillation returning after a procedure called ablation. It may help your doctor find irregular heartbeats early.
Delray Beach, FloridaAges 18 years+ - NCT06395870RecruitingPhase 1
Dual-target cell therapy for returning B-cell lymphoma
This trial tests a new cell therapy that targets two proteins (CD19 and CD20) found on certain lymphoma cells. It is for patients whose B-cell non-Hodgkin lymphoma has come back or not responded to at least two prior treatments. The goal is to see if this therapy can help control the cancer.
Hefei, AnhuiAges 18–75 - NCT06480604Recruiting
Probiotic for yeast infection prevention
This trial tests if taking a multi-strain probiotic daily can prevent repeat yeast infections in women who have had at least three infections in the past year.
Vadodara, GujaratAges 18–50 - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT07657325Recruiting
Toripalimab for high-risk kidney cancer that has been removed
This trial tests whether the drug toripalimab can prevent kidney cancer from coming back in people who have had their kidney and any visible metastases surgically removed. It focuses on patients with high-risk features or who had some metastatic spots taken out completely.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT06420063RecruitingPhase 1/Phase 2
Two-step CAR-T therapy for AML with CD33/CD123
This study tests a new kind of immunotherapy called CAR-T cells that are engineered to find and attack leukemia cells carrying certain markers (CD33, CD123, or CLL-1). The treatment is given in two steps, aiming to kill cancer cells more effectively and possibly with fewer side effects.
Beijing, Beijing MunicipalityAges 6–90
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Common questions
- Are there clinical trials for recurrent or metastatic solid tumors?
- Yes. Clin2 currently lists 3,299 recruiting recurrent or metastatic solid tumors studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrent or metastatic solid tumors trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrent or metastatic solid tumors trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.