Clinical trials
Recurrent or Metastatic Solid Tumors clinical trials
Below are recruiting recurrent or metastatic solid tumors clinical trials, each written for real people, not researchers. We’re tracking 3,299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07649122RecruitingPhase 3
PET Scan Imaging for Prostate Cancer Recurrence Detection
This study tests a new type of PET scan (a detailed imaging test) to find out if prostate cancer has come back after treatment. You'll receive an injection of a special tracer and then have a scan that takes pictures to help doctors locate any cancer.
Nanjing, JiangsuAges 18 years+ - NCT07653685RecruitingPhase 1/Phase 2
Study of a new drug with chemotherapy for advanced colorectal cancer
This trial tests a new drug (TQB2930) combined with chemotherapy, with or without another drug called bevacizumab, for people whose colorectal cancer has spread or cannot be removed by surgery and has a specific protein called HER2. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT07653893Recruiting
T-DXd for breast cancer that has spread to the brain
This study is looking at how well the drug trastuzumab deruxtecan (Enhertu) works for women and men with HER2-positive breast cancer that has spread to the brain. Researchers want to see how much of the drug gets into the spinal fluid and if it helps shrink brain tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07647198RecruitingPhase 2
Green tea extract and vitamin D to prevent fibroid return
This study tests whether two natural supplements—green tea extract (EGCG) and vitamin D—can help prevent uterine fibroids from coming back after treatment. You would take these supplements for 12 months while avoiding pregnancy.
Abu Dhabi, United Arab Emirates (uae)Ages 18 years+ - NCT05910801RecruitingPhase 2
Tafasitamab plus lenalidomide and venetoclax for relapsed lymphoma
This Phase 2 trial studies tafasitamab together with lenalidomide and venetoclax in people with mantle cell lymphoma (MCL) that has come back or did not respond to prior treatment. It may help shrink the lymphoma and improve disease control when standard options have not worked.
Rochester, MinnesotaAges 18 years+ - NCT06044623RecruitingPhase 3
Tailoring cancer pill dosing for older adults with breast cancer
This trial is testing whether adjusting the dose of a targeted therapy (CDK 4/6 inhibitor) based on a geriatric assessment can be as effective and safer for people aged 70 and older with advanced hormone receptor-positive, HER2-negative breast cancer. It aims to find the best dose to balance benefits and side effects.
HelsinkiAges 70 years+ - NCT07629830Recruiting
Phone-based asthma follow-up after emergency visits
This study tests whether regular phone calls and email check-ins after an asthma emergency-room visit can help prevent future asthma attacks. If you've recently had an asthma exacerbation (severe flare-up), this trial may help you stay healthier and avoid going back to the ER.
Tel AvivAges 18–75 - NCT07632339RecruitingPhase 2
New drug combination for recurrent head and neck cancer
This trial tests two drugs—becotatug vedotin and pucotenlimab—given before surgery to treat head and neck cancer that has come back in the same area. The goal is to shrink the tumor and help your body's immune system fight the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07631572Recruiting
Cesium implant radiation for recurrent cervical or uterine cancer
This study tests a type of internal radiation (cesium implant) to treat cancer that has come back in the vagina after previous pelvic radiation. The goal is to save the organ while treating the cancer.
Lexington, KentuckyAges 18 years+ - NCT06694883Recruiting
Ulcerative colitis remission-recurrence study
This trial studies people with ulcerative colitis who are in a 'remission-recurrence' state, meaning their symptoms come and go. It aims to better understand this pattern and may help guide future treatments.
Dongcheng, Beijing MunicipalityAges Any age - NCT06510283RecruitingPhase 2
Taitacept for refractory or recurrent autoimmune encephalitis
This trial tests a new drug called Taitacept for people with autoimmune encephalitis (brain inflammation caused by the immune system) that has not improved with standard treatments or has returned. The goal is to see if Taitacept can help control symptoms.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07625657Recruiting
CLIKX System for Ear Tube Placement Surgery
This trial tests a new device called CLIKX that helps doctors place small tubes in the eardrum to treat ear fluid and hearing problems. The study will evaluate whether this device works safely and effectively for patients needing ear tube surgery.
Louisville, KentuckyAges 6 months+ - NCT07621614RecruitingPhase 2
Safe Surgery Guidance for Childhood Melanoma Using Genetics
This study helps doctors decide the safest surgical approach for melanoma and similar skin tumors in children and young adults by using pathology reports and genetic information. The goal is to avoid unnecessary surgery while ensuring the best outcomes.
Oakland, CaliforniaAges Up to 25 years - NCT07627711RecruitingPhase 1/Phase 2
CAR-NK cells for advanced pancreatic cancer
This trial tests specially engineered immune cells (CAR-NK cells) designed to find and attack pancreatic cancer cells. The cells target specific proteins on cancer cells and may help people whose cancer has progressed despite prior treatment.
Shenzhen, GuangdongAges 18–75 - NCT07615049RecruitingPhase 3
Shorter versus standard radiation for soft tissue sarcoma
This trial compares a shorter course of radiation therapy with the standard longer course for people with soft tissue sarcoma in an arm or leg. The goal is to see if the shorter course works just as well and may be more convenient.
Birmingham, AlabamaAges 18 years+ - NCT02669953Recruiting
Aflibercept injections for persistent wet macular degeneration
This trial studies whether aflibercept injections can help when “wet” age-related macular degeneration is recurring or not fully going away. It focuses on adults who have already had ranibizumab and still have measurable vision in the study eye.
ViennaAges 50 years+ - NCT07619521RecruitingPhase 1/Phase 2
Combination drug therapy for advanced pancreatic cancer
This trial tests two targeted drugs, selumetinib and DS-8201a (trastuzumab deruxtecan), for advanced pancreatic cancer that has spread or cannot be removed. The combination may help people whose tumors have specific markers (KRAS mutation and HER2 positivity).
New Haven, ConnecticutAges 18 years+ - NCT07613645Recruiting
Lifestyle changes to prevent recurring C. difficile infection
This study tests whether specific lifestyle changes during treatment for C. difficile infection (a serious gut bacteria infection) can help prevent it from coming back. You'll receive standard antibiotic treatment and follow a controlled diet while researchers track your recovery.
Ann Arbor, MichiganAges 18 years+ - NCT07615348RecruitingPhase 2
CD70 imaging to guide treatment breaks in advanced kidney cancer
This trial tests whether a special type of imaging scan (CD70-targeted PET/CT) can help doctors safely pause treatment in patients with advanced kidney cancer who respond well to standard immunotherapy and targeted therapy. The goal is to reduce unnecessary treatment while keeping the cancer controlled.
Nanjing, JiangsuAges 18 years+ - NCT07616986Recruiting
Laser heat treatment for early-returning brain cancer
This trial tests a minimally invasive laser procedure (LITT) to treat glioblastoma that comes back very soon after initial treatment. The goal is to see if laser heat can destroy the tumor before standard radiation and chemotherapy begin, potentially improving outcomes.
BernAges 18 years+ - NCT07611656Recruiting
Surgery to Fix Septate Uterus Before IVF Treatment
This study tests whether a minimally invasive surgery to remove a uterine septum (a wall dividing the uterus) improves pregnancy success rates in IVF. You would have the procedure before starting IVF treatment if your uterus has this condition and you've had difficulty getting pregnant.
Changsha, HunanAges 20–40 - NCT07611838Recruiting
Predicting ABPA Recurrence Using Blood and Immune Markers
This study helps doctors predict whether allergic bronchopulmonary aspergillosis (ABPA)—a serious lung condition caused by fungal allergy—will come back after treatment. Researchers will analyze blood samples and immune system markers to identify patients at higher risk of relapse, which could improve how doctors monitor and treat you.
Jinan, ShandongAges 18–80 - NCT07603856RecruitingPhase 2
Combining Immunotherapy and Radiation for Advanced Lung Cancer
This study tests whether adding focused radiation therapy to immunotherapy can help patients with advanced non-small cell lung cancer whose cancer has progressed despite prior immunotherapy. The goal is to see if this combination works better than immunotherapy alone.
Chicago, IllinoisAges 18 years+ - NCT07611136Recruiting
Brain Vessel Disease Progression After Different Stroke Types
This study examines how small blood vessel disease in the brain progresses differently depending on whether you've had a recent stroke. Researchers will use MRI scans to track changes over time and better understand this condition.
Ulm, Baden-WurttembergAges 18 years+
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Common questions
- Are there clinical trials for recurrent or metastatic solid tumors?
- Yes. Clin2 currently lists 3,299 recruiting recurrent or metastatic solid tumors studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrent or metastatic solid tumors trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrent or metastatic solid tumors trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.