Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04962061Recruiting
Multidomain program to help prevent memory decline
This trial tests a combined lifestyle/health program to help prevent thinking and memory problems in older adults with cardiovascular risk factors. It may help by improving activity, health habits, and overall brain health over time.
Montreal, QuebecAges 60 years+ - NCT03903835RecruitingPhase 3
Biomarker-guided treatment for metastatic prostate cancer
This Phase 3 trial tests a prostate cancer treatment plan chosen using your tumor’s biomarker results. It aims to improve outcomes for men with metastatic prostate cancer starting first systemic treatment.
AalstAges 18 years+ - NCT04172025Recruiting
Swiss database for tracking hard-to-treat infections
This study builds a Swiss database using lab genetic testing (whole genome sequencing) plus basic patient information to track outbreaks of serious, drug-resistant, and sometimes high-infectious pathogens. Your data could help researchers understand how these germs spread and how to better prevent them.
BaselAges Any age - NCT07112209Enrolling by invitation
Rezvilutamide plus chemo for prostate cancer
This study tests a new combination treatment (Rezvilutamide plus docetaxel chemotherapy) for men with advanced prostate cancer that has stopped responding to abiraterone. The goal is to see if this combination can help control the cancer.
Guangzhou, GuangdongAges 18 years+ - NCT07155967Enrolling by invitation
Blood flow restriction training for leg strength in older women
This trial tests whether a type of strength training that partly uses blood flow restriction can help older women build leg strength on one side, which may also benefit the other leg. It's for women who are generally healthy and have not had recent leg injuries or surgeries.
Presidente Prudente, São PauloAges 60 years+ - NCT06065748RecruitingPhase 3
New hormone therapy for advanced breast cancer after prior treatment
This trial tests a new oral hormone therapy, giredestrant, against a standard hormone therapy (fulvestrant) when both are given with a CDK4/6 inhibitor. It is for people with advanced ER-positive, HER2-negative breast cancer that has come back after initial hormone therapy, and who have not yet had other treatments for advanced disease.
Daphne, AlabamaAges 18 years+ - NCT06529549Recruiting
Organoid drug test for advanced prostate cancer
This trial uses a lab test on a tiny sample of your tumor (called an organoid) to find which drug might work best for your advanced prostate cancer. It's for men whose cancer has stopped responding to hormone therapy and got worse after first treatment.
Guangzhou, GuangdongAges 18–75 - NCT06536803Recruiting
Strength training with or without stretching for plantar fasciitis
This study tests whether adding specific stretches for the plantar fascia to high-load strength training helps male athletes with plantar fasciitis feel better. It compares strength training alone to strength training plus targeted stretching.
Mirpur MatheloAges 20–35 - NCT06518382Recruiting
Study of leftover tumor after chemo and trastuzumab
This study looks at leftover breast cancer cells (after chemo and targeted therapy) to find out why some cells resist treatment. It may help doctors better understand how to treat HER2-positive breast cancer in the future.
Milan, LombardyAges 18 years+ - NCT06343298RecruitingPhase 2
Testing MANP for hard-to-control high blood pressure
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Little Rock, ArkansasAges 18–80 - NCT06902298RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for depression
This trial tests a new, non-invasive ultrasound treatment for people with depression who haven't gotten enough relief from at least two prior treatments. It uses sound waves to gently stimulate areas of the brain linked to mood.
Salt Lake City, UtahAges 18–65 - NCT04460313Recruiting
Testing bacteria in children’s noses and ears
This study looks at bacteria (especially pneumococcus) in the nose and throat of children. It includes children with ear infections or healthy children, to understand which germs are carried and how they relate to illness.
CréteilAges 6 months–15 years - NCT05818683RecruitingPhase 1
Pasritamig plus other drugs for advanced prostate cancer
This Phase 1 study tests pasritamig (JNJ-78278343) combined with other prostate cancer treatments in people with advanced prostate cancer that has spread. It aims to find the safest dose and see whether the combinations can help slow the cancer.
Sarasota, FloridaAges 18 years+ - NCT06396247RecruitingPhase 2/Phase 3
Daily leg exercises to improve walking
This study tests a simple daily leg-strengthening routine to see if it helps people who have trouble walking short distances. You'll do easy resistance exercises at home, which might make it easier to walk and move around.
Hershey, PennsylvaniaAges 65 years+ - NCT06353854Recruiting
Study of biomarkers in MSI-high colorectal cancer patients on immunotherapy
This trial is studying people with a specific type of advanced colorectal cancer (MSI-high/dMMR) who are starting immunotherapy with pembrolizumab. The goal is to find out which markers in the tumor might predict whether the treatment works well.
BayonneAges 18 years+ - NCT06849817Recruiting
Protein and exercise for postmenopausal women's health
This study tests whether adding more protein to your diet along with regular exercise can improve health and well-being in women over 50 who have gone through menopause.
Fayetteville, ArkansasAges Any age - NCT03041883Recruiting
Crosslinking to help a KPro eye resist corneal melting
This trial tests a treatment called corneal collagen crosslinking to strengthen the tissue under a KPro type I (an artificial cornea). It may help reduce the risk of corneal melting in people who need a KPro.
Montreal, QuebecAges 18–80 - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07514364RecruitingPhase 4
Rifabutin for Mycobacterium abscessus lung infection
This study tests whether an antibiotic called rifabutin works better for treating a difficult lung infection (Mycobacterium abscessus) that resists a common antibiotic. You may qualify if you've been diagnosed with this infection and your lab tests show it can resist clarithromycin.
TaipeiAges 18 years+ - NCT06193486RecruitingPhase 1
T-Cell Therapy for Advanced Prostate Cancer with Bone Spread
This trial tests a new type of immune cell therapy (gamma delta T cells) targeted at a marker on prostate cancer cells to see if it can shrink bone metastases in advanced, castration-resistant prostate cancer. It’s for men who have already tried chemotherapy and newer hormone therapies and whose cancer is getting worse.
Tampa, FloridaAges 18 years+ - NCT07237971Recruiting
Making medicine use better in Elche
This study works with the community to find ways to use medications like antidepressants, blood pressure drugs, and antibiotics more wisely. It is a collaboration among residents, healthcare workers, and local groups to create solutions together.
Elche, AlicanteAges 18 years+ - NCT07646405Recruiting
Electrical stimulation and light resistance training for older adults' muscles
This study tests whether combining electrical muscle stimulation (a gentle electrical current applied to muscles) with light resistance exercises can help adults over 65 build stronger leg muscles and improve their ability to walk and move around.
Lahore, Punjab ProvinceAges 65–85 - NCT05116579Recruiting
Using blood DNA tests to track PARP inhibitor response
This trial uses a blood test (circulating tumor DNA) to see whether PARP inhibitors are working for certain men with advanced prostate cancer. It may help predict which treatment responses are likely and monitor changes over time.
Guangzhou, GuangdongAges 18–75 - NCT07192120RecruitingPhase 1/Phase 2
MHB048C for advanced solid tumors
This trial is testing a new medicine called MHB048C for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it can help shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18 years+
Hear when a new Resistance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,200 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.