Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT07828847Recruiting
Exercise and muscle health in older adults with diabetes
This study looks at how exercise affects muscle cell function in older adults with type 2 diabetes and frailty. It may help find ways to improve strength and independence in aging.
ValenciaAges 18–83 - NCT03596476Recruiting
Test for reflux causes after proton pump pills fail
This study checks whether a special test of the esophagus after meals can find the exact reason for ongoing reflux symptoms when proton pump pills (PPIs) don’t help. It may help doctors choose the right next treatment for people whose reflux symptoms keep coming back.
Chambray-lès-ToursAges 18 years+ - NCT07820514Recruiting
Exercise during dialysis for kidney disease
This trial tests whether a structured exercise program during dialysis sessions can help people with chronic kidney disease feel better and improve their health. It is designed for patients who are stable on dialysis and may offer a way to enhance well-being during treatment.
Torre del GrecoAges 18 years+ - NCT07818109Enrolling by invitation
Risk factors for carrying resistant gut bacteria in the community
This study looks at why some healthy people carry resistant bacteria in their gut (called ESBL-producing bacteria). Researchers will collect stool and urine samples and ask about your daily life to find possible risk factors. You won't receive any treatment, but your participation can help scientists understand how to prevent the spread of these bacteria.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT05870475RecruitingPhase 2
Interferon plus ruxolitinib for hydroxyurea-resistant polycythemia vera
This Phase 2 trial tests a combination of pegylated interferon and ruxolitinib in adults with polycythemia vera who can’t tolerate hydroxyurea or don’t respond well to it. If you qualify, it may help control blood counts and disease symptoms when standard treatment hasn’t worked.
TianjinAges 18 years+ - NCT07817069Recruiting
Nitraria retusa tea for weight issues caused by clozapine
This trial tests whether a tea made from the plant Nitraria retusa can help reduce the weight gain and metabolic side effects caused by the medication clozapine. If you take clozapine for schizophrenia and have gained weight, this tea might help you manage that side effect.
SousseAges 18–65 - NCT06488586Recruiting
Ketamine vs Esketamine for treatment-resistant depression
This trial compares two forms of ketamine—given by IV or as a nasal spray—in people with major depression that hasn't improved after trying at least two other antidepressants. The goal is to see which treatment works better.
Kingston, OntarioAges 18–75 - NCT07802704RecruitingPhase 3
Study of risvutatug rezetecan for advanced prostate cancer
This trial tests an experimental drug called Risvutatug Rezetecan for men with advanced prostate cancer that has stopped responding to standard hormone therapy. The drug works by targeting cancer cells and delivering a toxic agent directly to them, potentially slowing the cancer's growth.
Auchenflower, QueenslandAges 18 years+ - NCT06505421Recruiting
Eccentric exercise for fatigue in multiple sclerosis
This study tests whether a specific type of leg exercise (called eccentric exercise) can help reduce fatigue in people with Multiple Sclerosis. It involves walking and other exercises to see if they improve how tired you feel.
New York, New YorkAges 18–75 - NCT07802262Recruiting
Prenatal exercise and blood sugar regulation
This trial tests whether a supervised exercise program during weeks 24 to 30 of pregnancy helps regulate blood sugar levels. It may help support a healthier pregnancy by improving glucose control.
Conway, ArkansasAges 18–35 - NCT07801001Enrolling by invitation
Zinc supplements for women with polycystic ovary syndrome
This study tests whether taking zinc supplements can improve insulin resistance and reduce symptoms in women with polycystic ovary syndrome (PCOS). If you have PCOS and are not pregnant, you may be able to join.
DhakaAges 18–45 - NCT05609084Recruiting
Speech therapy before surgery for drug-resistant temporal epilepsy
This study tests an intensive pre-surgery speech rehabilitation program for people whose seizures come from the language-related area in the temporal part of the brain. The goal is to improve speech outcomes before planned epilepsy surgery.
BordeauxAges 16 years+ - NCT06529549Recruiting
Organoid drug test for advanced prostate cancer
This trial uses a lab test on a tiny sample of your tumor (called an organoid) to find which drug might work best for your advanced prostate cancer. It's for men whose cancer has stopped responding to hormone therapy and got worse after first treatment.
Guangzhou, GuangdongAges 18–75 - NCT06394492RecruitingPhase 3
Testing a new drug for platinum-resistant ovarian cancer
This study tests a new drug called SHR-A1921 for people with ovarian cancer that no longer responds to platinum chemotherapy. The goal is to see if it can shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06343038RecruitingPhase 1
A new targeted radiation drug for advanced prostate cancer
This trial tests a new radioactive drug (161Tb-SibuDAB) for men with metastatic prostate cancer that has grown despite standard treatments. It aims to find the right dose and see if it can shrink tumors.
BaselAges 18 years+ - NCT07778524RecruitingPhase 1
Alpelisib challenge test for body weight study
This study tests a single dose of a drug called alpelisib to see how it affects body weight and metabolism. It may help researchers understand how the drug could be used for weight-related conditions.
New York, New YorkAges 18–70 - NCT07780513Recruiting
Genetics of muscle insulin resistance study
This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.
San Antonio, TexasAges 18–75 - NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT07766954Enrolling by invitationPhase 1
Exercise program for older adults living at home
This trial tests a gymnastics and multi-exercise program for people aged 60 and older who live at home. The goal is to see if this program improves strength, balance, and overall health.
Salvador, Estado de BahiaAges 60–105 - NCT06585007RecruitingPhase 3
Radiation for limited cancer growth in castration-resistant prostate cancer
This trial tests whether giving focused radiation to limited areas of cancer growth (up to 3 spots) can help control the disease in men with castration-resistant prostate cancer. You may be eligible if your cancer is growing slowly and you are already on hormone therapy.
LeuvenAges 18 years+ - NCT07753720RecruitingPhase 4
Daily tadalafil with or without another treatment for erectile dysfunction
This study tests whether taking tadalafil daily, either alone or with a second treatment, works better for men with erectile dysfunction who have not responded to on-demand pills. It aims to help men who have not had success with current treatments.
CairoAges 18–70
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,199 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.