Clinical trials
Retinal Dystrophies clinical trials
Below are recruiting retinal dystrophies clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07656753RecruitingEarly Phase 1
Gene therapy trial for RLBP1-related retinal dystrophy
This trial tests an injection (PUMCH-E111) for people with a specific genetic form of inherited retinal dystrophy caused by RLBP1 mutations. It aims to see if the treatment is safe and can help preserve vision.
Beijing, Beijing MunicipalityAges 18–55 - NCT06177977Recruiting
New imaging test for early-onset retinal disease
This study tests a new type of eye imaging to better detect and diagnose early-onset retinal dystrophies in children up to 8 years old. It may help find these conditions sooner and guide treatment.
Durham, North CarolinaAges birth–8 years - NCT07002398RecruitingPhase 1/Phase 2
Gene therapy for Stargardt disease (VG801)
This trial tests a new gene therapy called VG801 for people with Stargardt disease, a genetic condition that causes vision loss. The treatment aims to improve or slow vision loss by delivering a working copy of the ABCA4 gene to the retina.
Shanghai, Shanghai MunicipalityAges 6 years+ - NCT05976139Recruiting
Micropulsed laser for swelling in inherited retina conditions
This study tests whether a micropulsed laser can reduce swelling in the macula (central vision area) in people with inherited retinal diseases. It may help improve or stabilize vision-related swelling seen on detailed eye scans.
Rome, RMAges 18–80 - NCT05858983RecruitingPhase 1/Phase 2
Gene therapy for certain RPE65 inherited eye conditions
This early-stage trial tests a gene therapy aimed at treating inherited retinal dystrophy caused by changes in the RPE65 gene on both copies. It may help slow vision loss or improve eye function, but the study is mainly about safety and learning how the treatment works.
Beijing, Beijing MunicipalityAges 8–45 - NCT04648124Recruiting
MRI brain scan study in hereditary retinal vision loss
This study uses functional MRI (a type of brain scan) to understand how the brain processes vision in people with inherited retinal disorders. You might be included if you are an adult with hereditary retinal degeneration and are planning certain vision-related treatments soon.
Paris, PARISAges 18 years+ - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT02014389Recruiting
Testing pupil measurements with colored light in eye exams
This study checks how well a device can measure how your pupils respond to colored light. It may help improve eye testing, especially when monitoring certain vision and nerve conditions.
Tel LitwinskyAges 18–80 - NCT06375239Recruiting
Study of tests for tracking vision in retinal disease
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
Irvine, CaliforniaAges 18 years+ - NCT07502664Recruiting
A study on vision and navigation in inherited retinal disease
This study is looking at how people with inherited retinal disease that affects peripheral vision see and move around. It will test a new way to measure vision and navigation to see if it can help doctors understand how the disease affects daily life.
Irvine, CaliforniaAges 18 years+ - NCT06319872RecruitingPhase 1
Study of disulfiram for vision in retinal degeneration
This trial tests whether disulfiram, a drug used for alcohol use disorder, can improve vision in people with retinal degeneration. You must have an alcohol use diagnosis and agree to avoid alcohol for 6 months.
Rochester, New YorkAges 18 years+ - NCT07085533Recruiting
A Study of Inherited Retinal Diseases
This study is looking at how inherited retinal diseases affect color vision over time. It may help researchers understand these conditions better and is a good fit for people with a known diagnosis who can describe what they see.
WuhanAges Any age - NCT05626920RecruitingPhase 1/Phase 2
Disulfiram trial for inherited vision loss in one eye
This early-stage study tests whether disulfiram can help preserve vision in people with inherited retinal degeneration. It focuses on one study eye and uses strict eye, blood/liver, and alcohol-avoidance rules because the medicine can affect the body and needs careful safety monitoring.
Seattle, WashingtonAges 18 years+ - NCT05809635Recruiting
Study for BEST1-related macular eye disease
This trial is studying people with BEST1-associated vitelliform macular dystrophy, a genetic eye condition affecting central vision. It will involve several eye-related study visits over about three years, aiming to better understand the condition and how it is managed.
New York, New YorkAges Any age - NCT05355415Recruiting
Eye imaging study for outer retina diseases using adaptive optics
This study uses a special, high-detail eye imaging machine to take clear pictures of the outer retina. It may help researchers understand these eye conditions better, and how the eye images look when people have an outer retinal disease.
Bethesda, MarylandAges 21 years+ - NCT06787482RecruitingPhase 1/Phase 2
Peptide therapy for retinitis pigmentosa
This trial tests a new peptide therapy for people with retinitis pigmentosa (RP), a genetic eye disease that causes vision loss. The goal is to see if the treatment is safe and can help slow or improve vision loss.
CairoAges Any age - NCT05589714Recruiting
Study your rare eye gene and track retinal disease over time
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
Little Rock, ArkansasAges 4 years+ - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT07063030RecruitingEarly Phase 1
Gene therapy trial for AIPL1-related eye disease
This trial tests a gene therapy called LX107 for people with vision loss caused by changes in the AIPL1 gene. It aims to see if the treatment is safe and can improve vision.
ShanghaiAges 4 years+ - NCT07529041Enrolling by invitation
Sound cues to help eyes stay still during eye exams
This study tests whether audio feedback (beeping sounds) can help people keep their eyes steady during eye imaging tests. If your eyes move around during exams, this technology might help you stay focused and get better-quality images for diagnosis.
GöttingenAges 18 years+ - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT07341763Recruiting
Brain stimulation for better mobility in vision loss
This study tests whether a safe, noninvasive brain stimulation technique (called tDCS) can help people with vision loss from retinitis pigmentosa, rod-cone dystrophy, or advanced glaucoma move around more easily and safely. Participants will do walking and orientation tasks while receiving the stimulation.
Waterloo, OntarioAges 18 years+ - NCT07548944Recruiting
How Electrical Stimulation Affects Your Vision
This study watches how a treatment called transcorneal electrical stimulation (TES)—which uses gentle electrical pulses on your eye—affects your vision in the short term. You'll be observed while using the OkuStim device, and researchers will ask about any improvements you notice in your sight.
Frankfurt am MainAges 18 years+
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Retinal Dystrophies trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for retinal dystrophies?
- Yes. Clin2 currently lists 25 recruiting retinal dystrophies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a retinal dystrophies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a retinal dystrophies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.