Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 385 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07089576Recruiting
Study of the Arcevo LSA device for aortic arch repair
This trial tests a new device called Arcevo LSA to treat certain types of aortic arch problems, like dissections (tears) or aneurysms (bulges). It is for people who need open surgery, and the device helps fix the left subclavian artery area.
Birmingham, AlabamaAges 18–80 - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
BeijingAges 70 years+ - NCT04905056RecruitingPhase 2
Ablation treatment for lung ground-glass nodules that don’t go away
This Phase 2 trial studies whether a procedure called “ablation” is safe and effective for certain lung cancers that appear as ground-glass spots on CT scans and do not improve after 3 months. It may help people who cannot fully have surgery for their condition.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT04888975Recruiting
Device study for one-arm swelling after lymph surgery
This study tests a medical device (Dayspring Technology) to reduce swelling in the arm caused by breast cancer treatment and lymph surgery. You may be eligible if you have one-sided arm swelling after lymphatic surgery and meet safety checks for the device.
Palo Alto, CaliforniaAges 18 years+ - NCT04733404Recruiting
Dragonfly device study for functional mitral valve leakage
This trial tests a catheter-based procedure (putting a small device through blood vessels) to repair a leaking mitral valve caused by heart muscle problems. It aims to reduce symptoms and improve heart function and safety in people who are still having heart failure symptoms despite standard treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT05690802Recruiting
Test palonosetron to prevent nausea from chemotherapy
This trial studies whether palonosetron helps prevent nausea and vomiting caused by chemotherapy that has a moderate risk of vomiting. It may help you feel more comfortable during chemo and avoid treatment interruptions from severe nausea.
Xi'an, Shaan'xiAges 18–75 - NCT05536102RecruitingPhase 2
Surgery-plus chemo and immunotherapy for HER2-negative gastric cancer
This Phase 2 trial studies whether adding two medicines (XELOX and tislelizumab) and another chemotherapy drug (PLD) around the time of surgery works better and is safe for people with stage III gastric (stomach) cancer. It is designed for tumors that are HER2-negative and PD-1/L1 positive.
ShanghaiAges 18–75 - NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06417567Recruiting
Preventing nausea and vomiting after GI cancer surgery
This study tests whether the medication NEPA (Netupitant and Palonosetron) can prevent nausea and vomiting in people who have had surgery for liver, gallbladder, or pancreatic cancer. It may help those who want to avoid post-surgery sickness.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07851623RecruitingPhase 1
Inhaled study drug for healthy adults and adults with asthma
This early-phase study tests an inhaled medication (CHF10136) to see if it's safe and how the body handles it. It includes both healthy adults and people with asthma, and participants will be monitored closely throughout.
LeedsAges 18–65 - NCT06425224RecruitingPhase 3
TENS therapy for premature ejaculation
This trial tests if a painless electrical nerve stimulation (TENS) treatment can help men with premature ejaculation last longer and feel more in control. It's for men who have had this condition for at least 6 months and are in a stable relationship.
Mexico CityAges 18–62 - NCT06441110RecruitingPhase 3
BCG instillation for medium- to high-risk bladder cancer
This trial tests whether a specific schedule of BCG (a weakened germ that boosts the immune system) placed directly into the bladder is safe and effective for medium- to high-risk bladder cancer that hasn't grown into the muscle. It aims to see if adjusting the standard BCG course can work better for people with a PD-L1-positive tumor.
Fuzhou, FujianAges 18–75 - NCT05516004RecruitingPhase 2
Cornea strengthening treatment study for thinning corneas
This Phase 2 study tests whether a procedure called PXL‑Platinum 330 can safely and effectively strengthen corneas that are thinning (such as keratoconus or related conditions). It aims to see if the treatment can help stabilize or improve the cornea’s shape while keeping side effects low.
Boca Raton, FloridaAges 18 years+ - NCT07832318Recruiting
Herbal injection for chronic sciatica
This trial tests whether an herbal injection into acupuncture points can safely reduce leg pain from sciatica that has lasted more than 3 months. It compares this treatment to usual care, and may offer a new option for people who haven't found relief.
Bucheon-si, Gyeonggi-doAges 19–70 - NCT07809256RecruitingPhase 3
Combination treatment for advanced lung cancer with a RET gene change
This trial tests a combination of two medicines (pembrolizumab and lenvatinib) for people with advanced non-small cell lung cancer that has a specific RET gene change. The treatment may help slow down or shrink the cancer, and the study checks how well people tolerate it.
Saint PetersburgAges 18 years+ - NCT07805928Recruiting
A guided pain plan after rib remodeling surgery
This study tests a step-by-step pain management plan guided by your pain scores after rib remodeling surgery. The plan uses a mix of medications to reduce pain safely and may help you recover with less discomfort.
BogotáAges 18–55 - NCT07805915Recruiting
Tummy tuck muscle tightening study
This study tests a new tummy tuck technique that also tightens the abdominal muscles. It may help patients with separated stomach muscles feel and look better after surgery.
MedellínAges 18 years+ - NCT07784296Recruiting
Triple combination therapy for high blood pressure in Korean adults
This study tests a three-drug combination pill for high blood pressure in Korean adults. It aims to see if this treatment is safe and effective.
Gyeonggi-doAges Any age - NCT06539481RecruitingPhase 4
ILUVIEN eye implant for kids with recurrent eye inflammation
This trial tests an eye implant (ILUVIEN) in children and teens ages 6 to 17 who have a type of eye inflammation called uveitis that keeps coming back. The implant releases medicine slowly over time to control inflammation and may help reduce the need for other treatments.
BerlinAges 6–17 - NCT07779252RecruitingPhase 3
Study of a new treatment for frown lines between the eyebrows
This study tests a new medication (IPN10200) to safely reduce moderate to severe frown lines between the eyebrows in adults. It may help if you are bothered by these lines and are looking for a non-surgical option.
Guangzhou, GuangdongAges 18 years+ - NCT07772492RecruitingPhase 3
Study of upadacitinib for teens with severe hair loss
This study tests if upadacitinib can help young people with severe alopecia areata (a condition causing patchy hair loss) regrow their hair. It may be an option if hair loss has been present for less than 8 years and there has been no recent improvement.
Los Angeles, CaliforniaAges 6–17 - NCT07774598Recruiting
Non-invasive nerve stimulation for essential tremor
This trial is testing whether a device that gently stimulates the nerves in your arm (called non-invasive neuromodulation) can safely reduce hand tremors over a long period. It might help with activities like eating, writing, or dressing.
ShanghaiAges 18–75
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 385 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.